• Publications
  • Influence
Prefrontal Cortex HCN1 Channels Enable Intrinsic Persistent Neural Firing and Executive Memory Function
In many cortical neurons, HCN1 channels are the major contributors to Ih, the hyperpolarization-activated current, which regulates the intrinsic properties of neurons and shapes their integration ofExpand
  • 52
  • 7
  • PDF
Differential contribution of TRPM4 and TRPM5 nonselective cation channels to the slow afterdepolarization in mouse prefrontal cortex neurons
In certain neurons from different brain regions, a brief burst of action potentials can activate a slow afterdepolarization (sADP) in the presence of muscarinic acetylcholine receptor agonists. TheExpand
  • 31
  • 7
  • PDF
Increased Size and Stability of CA1 and CA3 Place Fields in HCN1 Knockout Mice
Hippocampal CA1 and CA3 pyramidal neuron place cells encode the spatial location of an animal through localized firing patterns called "place fields." To explore the mechanisms that control placeExpand
  • 65
  • 4
  • PDF
Phosphorylation of CREB and DARPP‐32 during late LTP at hippocampal to prefrontal cortex synapses in vivo
Specific patterns of stimulation applied in the ventral hippocampus produce long‐term potentiation (LTP) of postsynaptic synapses in the prefrontal cortex in vivo. The induction of LTP is dependentExpand
  • 26
  • 3
D1 receptor modulation of memory retrieval performance is associated with changes in pCREB and pDARPP-32 in rat prefrontal cortex
We have recently shown a significant role of dopamine D(1) receptors in recognition and temporal order memory retrieval for objects in rodents [Hotte M, Naudon L, Jay TM. Modulation of recognitionExpand
  • 60
  • 2
Group I mGluRs modulate the pattern of non-synaptic epileptiform activity in the hippocampus
The hippocampus is well known for its susceptibility to epileptic seizures, in part because of its neuronal architecture that facilitates synchronization. Although synaptic networks are important forExpand
  • 30
  • 1
A two-way street
therefore observed the full spatial pattern and temporal development of neural activity, making the link to behavior unambiguous. The differential on-contour increase and off-contour decrease ofExpand
  • 23
The RNAs of ALS
are kept separate throughout the processing chains that support choice and monitoring under this framework. An intriguing alternative suggestion put forward by the authors is that accuracy isExpand
  • 2
The induction of long-term plasticity of non-synaptic, synchronized activity by the activation of group I mGluRs
It is well established that activation of group I metabotropic glutamate receptors (mGluRs) produces long-lasting alterations in synaptic efficacy. We now demonstrate that activation of mGluRs canExpand
  • 7