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Vorinostat

Known as: Octanedioic acid hydroxyamide phenylamide, SAHA, N-Hydroxy-N'-phenyl octanediamide 
A synthetic hydroxamic acid derivative with antineoplastic activity. Vorinostat, a second generation polar-planar compound, binds to the catalytic… 
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Background and Purpose— The purpose of these guidelines is to provide an up-to-date comprehensive set of recommendations for… 
Highly Cited
2012
Highly Cited
2012
Despite antiretroviral therapy, proviral latency of human immunodeficiency virus type 1 (HIV-1) remains a principal obstacle to… 
Highly Cited
2009
Highly Cited
2009
Lysine Acetylation Catalog Covalent posttranslational modification is an essential cellular regulatory mechanism by which the… 
Highly Cited
2009
Highly Cited
2009
Boron- and nitrogen-doped graphenes are are prepared by the arc discharge between carbon electrodes or by the transformation of… 
Review
2007
Review
2007
In our quest to understand why dimethyl sulfoxide (DMSO) can cause growth arrest and terminal differentiation of transformed… 
Highly Cited
2007
Highly Cited
2007
On October 6, 2006, the U.S. Food and Drug Administration granted regular approval to vorinostat (Zolinza(R); Merck & Co., Inc… 
Highly Cited
2007
Highly Cited
2007
The activity and safety of the histone deacetylase inhibitor vorinostat (suberoylanilide hydroxamic acid, SAHA) were evaluated in… 
Highly Cited
2007
Highly Cited
2007
PURPOSE To evaluate the activity and safety of the histone deacetylase inhibitor vorinostat (suberoylanilide hydroxamic acid) in… 
Review
2000
Review
2000
Histone deacetylase (HDAC) inhibitors have been shown to be potent inducers of growth arrest, differentiation, and/or apoptotic… 
Highly Cited
1999
Highly Cited
1999
Histone deacetylases (HDACs) mediate changes in nucleosome conformation and are important in the regulation of gene expression…