M344
National Institutes of Health
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M344 is a novel histone deacetylase inhibitor. There is no report on the effect of M344 treatment on the development of pig…
Hereditary tyrosinemia type I (HT1) is a rare disease caused by a deficiency of fumarylacetoacetate hydrolase (FAH) in the…
The molecular genetic basis of spinal muscular atrophy (SMA), an autosomal recessive neuromuscular disorder, is the loss of…
OBJECTIVE
Histone deacetylase inhibitors (HDACIs) can inhibit cell proliferation, induce cell cycle arrest, and stimulate…
Three monoclonal antibodies (mAbs), M344, M300 and M75, were shown to define a unique tumour-associated antigen (TAA) of…
The authors have further characterized the normal human tissue distribution and tumor expression of two highly restricted tumor…