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M344

 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Significance Hundreds of failed clinical trials with Alzheimer’s disease (AD) patients over the last fifteen years demonstrate… Expand
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2010
2010
BackgroundActivating Transcription Factor (ATF) 3 is a key regulator of the cellular integrated stress response whose expression… Expand
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Highly Cited
2010
Highly Cited
2010
PURPOSE Histone deacetylase inhibitors (HDACIs) can enhance the sensitivity of cells to photon radiation treatment (XRT) by… Expand
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Highly Cited
2007
Highly Cited
2007
The origin of malignant embryonal tumors is incompletely understood and certain risk groups remain difficult to treat. The… Expand
Highly Cited
2006
Highly Cited
2006
Proximal spinal muscular atrophy (SMA) is a common autosomal recessively inherited neuromuscular disorder causing infant death in… Expand
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Highly Cited
2006
Highly Cited
2006
Among a panel of histone deacetylase (HDAC) inhibitors investigated, suberoylanilide hydroxamic acid (SAHA) evolved as a potent… Expand
Highly Cited
2006
Highly Cited
2006
Maspin, a noninhibitory serine protease inhibitor, exerts multifaceted tumor-suppressive effects. Maspin expression is associated… Expand
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2006
2006
Objective. Histone deacetylase inhibitors (HDACIs) can inhibit cell proliferation, induce cell cycle arrest, and stimulate… Expand
2005
2005
Histone deacetylase (HDAC) inhibitors are a novel class of promising anti-cancer agents. Little information is available on the… Expand
Highly Cited
2003
Highly Cited
2003
The Sir2 histone deacetylase gene family consists of seven mammalian sirtuins (SIRTs) which are NAD-dependent histone/protein… Expand
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