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Hydroxamic Acids

Known as: Hydroxamic Acids [Chemical/Ingredient], Hydroxamic Acid, Acid, Hydroxamic 
A group of weak acids with the general chemical formula RC(=O)N(R')OH and antineoplastic and antimicrobial activities. Hydroxamic acids covalently… 
National Institutes of Health

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2,6-pyridinedicarbohydroxamic acid2-nitroimidazole-1-acetohydroxamic acid3,4,5-trihydroxybenzohydroxamic acidABT-770
In Bloodagonistsantagonists & inhibitorschemical synthesis

Papers overview

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2013
2013
Hydroxamic acids : a unique family of chemicals with multiple biological activities
Chemistry of Hydroxamic Acids.- Theoretical Studies on Hydroxamic Acids.- Hydroxamic Acids as Carbonic Anhydrase Inhibitors… 
1983
1983
Evidence for reduction of hydroxamic acids to the corresponding amides by liver aldehyde oxidase.
Recently, interest in hydroxamic acids has been stimulated because of their important biological activities and their clinical… 
1983
1983
Structural analysis of the inhibition of thermolysin by an active-site-directed irreversible inhibitor.
The mode of binding of the irreversible thermolysin inhibitor ClCH2CO-DL-(N-OH)Leu-OCH3 [Rasnick, D., & Powers, J.C. (1978… 
1981
1981
Methotrexate analogues. 13. Chemical and pharmacological studies on amide, hydrazide, and hydroxamic acid derivatives of the glutamate side chain.
Carbodiimide-mediated condensation of 4-amino-4-deoxy-N10-methylpteroic acid (APA) with several alkyl, aralkyl, and aryl amines… 
1971
1971
Acylation of carcinogenic hydroxamic acids by carbamoyl phosphate to form reactive esters.
1. Acylation of 2-(N-hydroxyacetamido)fluorene and several other aromatic hydroxamic acids by carbamoyl phosphate was studied and… 
1969
1969
Hydroxamic acids. II. Kinetics and mechanisms of hydroxyaminolysis of succinimide.
In alkaline pH at 40° succinimide simultaneously hydrolyzes to form succinamic acid and reacts with NH2OH to form N… 
1966
1966
Hydroxyurea derivatives: oxamyl hydroxamic acid.
Oxamyl hydroxamic acid (OHA), a derivative of hydroxyurea, was shown to inhibit the growth of Gram-negative bacteria; inhibition… 
1951
1951
Separation of saturated mono-hydroxamic acids by partition chromatography on paper.
  • A. Thompson
  • Australian journal of scientific research. Ser. B…
  • 1951
  • Corpus ID: 45957597
Separation of simple saturated hydroxamic acids with a chain length of one to nine carbon atoms has been achieved by partition… 
1950
1950
Salicylhydroxamic Acid as an Antitubercular Agent
SOME derivatives of salicylic acid possess antitubercular properties, the most important of such substances being the well-known… 
1949
1949
Analogs of aspergillic acid; various antibacterial heterocyclic hydroxamic acids.