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Hydroxamic Acids
Known as:
Hydroxamic Acids [Chemical/Ingredient]
, Hydroxamic Acid
, Acid, Hydroxamic
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A group of weak acids with the general chemical formula RC(=O)N(R')OH and antineoplastic and antimicrobial activities. Hydroxamic acids covalently…
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National Institutes of Health
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Related topics
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2,6-pyridinedicarbohydroxamic acid
2-nitroimidazole-1-acetohydroxamic acid
3,4,5-trihydroxybenzohydroxamic acid
ABT-770
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In Blood
agonists
antagonists & inhibitors
chemical synthesis
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Hydroxamic acids : a unique family of chemicals with multiple biological activities
Satya P. Gupta
2013
Corpus ID: 264269128
Chemistry of Hydroxamic Acids.- Theoretical Studies on Hydroxamic Acids.- Hydroxamic Acids as Carbonic Anhydrase Inhibitors…
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1985
1985
Formation of DNA adducts in vivo in rat liver and intestinal epithelium after administration of the carcinogen 3,2'-dimethyl-4-aminobiphenyl and its hydroxamic acid.
J. Westra
,
T. Flammang
,
N. Fullerton
,
F. Beland
,
C. Weis
,
F. Kadlubar
Carcinogenesis
1985
Corpus ID: 25907488
Administration of the 3H-labeled colon carcinogen, 3,2'-dimethyl-4-aminobiphenyl (DMABP) and its hydroxamic acid derivative, N…
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1983
1983
Evidence for reduction of hydroxamic acids to the corresponding amides by liver aldehyde oxidase.
K. Sugihara
,
S. Kitamura
,
K. Tatsumi
Chemical and pharmaceutical bulletin
1983
Corpus ID: 37384644
Recently, interest in hydroxamic acids has been stimulated because of their important biological activities and their clinical…
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1981
1981
Methotrexate analogues. 13. Chemical and pharmacological studies on amide, hydrazide, and hydroxamic acid derivatives of the glutamate side chain.
A. Rosowsky
,
C. S. Yu
,
J. Uren
,
H. Lazarus
,
M. Wick
Journal of Medicinal Chemistry
1981
Corpus ID: 23592270
Carbodiimide-mediated condensation of 4-amino-4-deoxy-N10-methylpteroic acid (APA) with several alkyl, aralkyl, and aryl amines…
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1973
1973
m-Chlorobenzhydroxyamic acid--an inhibitor of cyanide-insensitive respiration in Trypanosoma brucei.
D. Evans
,
R. Brown
The Journal of Protozoology
1973
Corpus ID: 32625787
SYNOPSIS Cyanide-insensitive respiration of bloodstream and culture forms of T. brucei was inhibited by m-chlorobenz-hydroxamic…
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1971
1971
Acylation of carcinogenic hydroxamic acids by carbamoyl phosphate to form reactive esters.
P. Lotlikar
,
L. Luha
Biochemical Journal
1971
Corpus ID: 1350010
1. Acylation of 2-(N-hydroxyacetamido)fluorene and several other aromatic hydroxamic acids by carbamoyl phosphate was studied and…
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1969
1969
Hydroxamic acids. II. Kinetics and mechanisms of hydroxyaminolysis of succinimide.
R. Notari
Journal of Pharmacy and Science
1969
Corpus ID: 450944
In alkaline pH at 40° succinimide simultaneously hydrolyzes to form succinamic acid and reacts with NH2OH to form N…
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1966
1966
Hydroxyurea derivatives: oxamyl hydroxamic acid.
G. Gale
Cancer Research
1966
Corpus ID: 37661768
Oxamyl hydroxamic acid (OHA), a derivative of hydroxyurea, was shown to inhibit the growth of Gram-negative bacteria; inhibition…
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1951
1951
Separation of saturated mono-hydroxamic acids by partition chromatography on paper.
A. Thompson
Australian journal of scientific research. Ser. B…
1951
Corpus ID: 45957597
Separation of simple saturated hydroxamic acids with a chain length of one to nine carbon atoms has been achieved by partition…
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1950
1950
Salicylhydroxamic Acid as an Antitubercular Agent
T. Urbański
Nature
1950
Corpus ID: 4293128
SOME derivatives of salicylic acid possess antitubercular properties, the most important of such substances being the well-known…
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