Certain photooxidized derivatives of tryptophan bind with very high affinity to the Ah receptor and are likely to be endogenous signal substances.
- A. Rannug, U. Rannug, A. Grafström
- Biology, ChemistryJournal of Biological Chemistry
- 15 November 1987
Structure-activity model of chemicals that cause human respiratory sensitization.
- C. Graham, H. Rosenkranz, M. Karol
- ChemistryRegulatory toxicology and pharmacology : RTP
- 1 December 1997
A structure-activity model of chemicals with the potential to cause respiratory allergy developed through the CASE/MultiCASE systems is applicable to initial prediction of the sensitizing ability of untested chemicals and may provide mechanistic insight into the process(es) of respiratory sensitization.
Discodermolide, a cytotoxic marine agent that stabilizes microtubules more potently than taxol.
- E. ter Haar, R. Kowalski, B. Day
- 9 January 1996
Discodermolide arrests Burkitt lymphoma cells in mitosis and shows spectacular rearrangement of the microtubule cytoskeleton, including extensive microtubules bundling in breast carcinoma cells.
The extraordinary mutagenicity of nitropyrenes in bacteria.
- R. Mermelstein, D. K. Kiriazides, M. Butler, E. McCoy, H. Rosenkranz
- Chemistry, BiologyMutation research
- 1 July 1981
Determining the DNA-Modifying Activity of Chemicals Using DNA-Polymerase-Deficient Escherichia coli
- H. Rosenkranz, Z. Leifer
The Salmonella mutagenicity assay procedure recently developed by Ames et al. has shown a remarkable ability to detect carcinogens as microbial mutagens.
Reproducibility of microbial mutagenicity assays: II. Testing of carcinogens and noncarcinogens in Salmonella typhimurium and Escherichia coli.
The intra- and interlaboratory reproducibility of the Salmonella assay with regard to the overall judgment of mutagenic or nonmutagenic was good, but the results in the E coli strain exhibited a high degree of variability between laboratories.
Diesel Exhaust : A Critical Analysis of Emissions , Exposure , and Health · Effects
- H. Rosenkranz
- Environmental Science
The basis of the insensitivity of Salmonella typhimurium strain TA98/1,8-DNP6 to the mutagenic action of nitroarenes.
- E. McCoy, M. Anders, H. Rosenkranz
- Biology, ChemistryMutation research
- 1 July 1983
Carcinogenic and mutagenic activities of safrole, 1'-hydroxysafrole, and some known or possible metabolites.
- P. Wislocki, E. Miller, J. Miller, E. McCoy, H. Rosenkranz
- Biology, ChemistryCancer Research
- 1 June 1977
The carcinogenic and mutagenic activities of metabolites and possible metabolites of safrole and 1′-hydroxysafrole were investigated as guides to their importance as possible proximate or ultimate…
Structural basis of carcinogenicity in rodents of genotoxicants and non-genotoxicants.
- H. Rosenkranz, G. Klopman
- BiologyMutation research
- 1 February 1990