Positive Regulation of Apoptosis
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Various proteins adsorb spontaneously on the sidewalls of acid-oxidized single-walled carbon nanotubes. This simple nonspecific… Expand Reactive oxygen species (ROS) and mitochondria play an important role in apoptosis induction under both physiologic and… Expand During apoptosis, the mitochondrial network fragments. Using short hairpin RNAs for RNA interference, we manipulated the… Expand Cancer cells often develop resistance to chemotherapy or irradiation through mutations in the p53 tumour-suppressor gene, which… Expand The Ca2+-activated protein phosphatase calcineurin induces apoptosis, but the mechanism is unknown. Calcineurin was found to… Expand Apoptosis is a physiological process critical for organ development, tissue homeostasis, and elimination of defective or… Expand Anucleate cells can be induced to undergo programmed cell death (PCD), indicating the existence of a cytoplasmic PCD pathway that… Expand Programmed cell death (PCD) is a physiological process commonly defined by alterations in nuclear morphology (apoptosis) and/or… Expand David E. Fisher Division of Pediatric Hematology/Oncology Dana Farber Cancer Institute and The Children’s Hospital Harvard… Expand To characterize cell surface molecules involved in control of growth of malignant lymphocytes, monoclonal antibodies were raised… Expand