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Positive Regulation of Apoptosis

Known as: up-regulation of apoptosis, Induction of Apoptosis, upregulation of apoptosis 
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process. [GOC:jl, GOC:mtg_apoptosis]
National Institutes of Health

Related topics

Related topics

50 relations
2-methoxyestradiol (nanocrystal colloidal dispersion)ANP32B wt AlleleARHGEF7 wt AlleleApoptotic BCL2L1-Antisense Long Non-Coding RNA, human

Narrower (1)

activation of apoptosis

Broader (1)

biological control

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
A novel anticancer gold(III) dithiocarbamate compound inhibits the activity of a purified 20S proteasome and 26S proteasome in human breast cancer cell cultures and xenografts.
Although cisplatin has been used for decades to treat human cancer, some toxic side effects and resistance are observed. It has… 
Highly Cited
2004
Highly Cited
2004
Essential role of caspases in epigallocatechin-3-gallate-mediated inhibition of nuclear factor kappaB and induction of apoptosis
Green tea constituent (−) epigallocatechin-3-gallate (EGCG) has shown remarkable cancer-preventive and some cancer-therapeutic… 
Highly Cited
2004
Highly Cited
2004
Sensitization for anticancer drug-induced apoptosis by the chemopreventive agent resveratrol
Current attempts to improve the survival of cancer patients largely depend on strategies to target tumor cell resistance… 
Highly Cited
2004
Highly Cited
2004
Nanosecond pulsed electric fields modulate cell function through intracellular signal transduction mechanisms.
These studies describe the effects of nanosecond (10-300 ns) pulsed electric fields (nsPEF) on mammalian cell structure and… 
Highly Cited
2003
Highly Cited
2003
Reactive oxygen species-dependent c-Jun NH2-terminal kinase/c-Jun signaling cascade mediates neuroblastoma cell death induced by diallyl disulfide.
The pharmacological properties of garlic and its derivatives are long known, and their underling mechanisms are being extensively… 
Highly Cited
1999
Highly Cited
1999
TNF-alpha and IL-10 modulate the induction of apoptosis by virulent Mycobacterium tuberculosis in murine macrophages.
The Bcg/Nramp1 gene controls early resistance and susceptibility of macrophages to mycobacterial infections. We previously… 
Highly Cited
1998
Highly Cited
1998
Essential role of p53 in phenethyl isothiocyanate-induced apoptosis.
Phenethyl isothiocyanate (PEITC) is a natural product that is among the most effective cancer chemopreventive agents known… 
Highly Cited
1997
Highly Cited
1997
Cytochrome c-dependent and -independent Induction of Apoptosis in Multiple Myeloma Cells*
Cytochrome c is a mitochondrial protein that induces apoptosis when accumulated in the cytosol in response to diverse stress… 
Highly Cited
1996
Highly Cited
1996
Requirement of an ICE-Like Protease for Induction of Apoptosis and Ceramide Generation by REAPER
Genetic studies indicated that the Drosophila melanogaster protein REAPER (RPR) controls apoptosis during embryo development… 
Highly Cited
1995
Highly Cited
1995
Natural killer and lymphokine-activated killer cells require granzyme B for the rapid induction of apoptosis in susceptible target cells.
Granzyme (Gzm) B-deficient mice obtained by gene targeting were used to assess the role of Gzm B in the mechanisms used by… 
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