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Positive Regulation of Apoptosis

Known as: up-regulation of apoptosis, Induction of Apoptosis, upregulation of apoptosis 
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process. [GOC:jl, GOC:mtg_apoptosis]
National Institutes of Health

Related topics

Related topics

50 relations
2-methoxyestradiol (nanocrystal colloidal dispersion)ANP32B wt AlleleARHGEF7 wt AlleleApoptotic BCL2L1-Antisense Long Non-Coding RNA, human

Narrower (1)

activation of apoptosis

Broader (1)

biological control

Papers overview

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Highly Cited
2004
Highly Cited
2004
AIF deficiency compromises oxidative phosphorylation
Apoptosis‐inducing factor (AIF) is a mitochondrial flavoprotein that, after apoptosis induction, translocates to the nucleus… 
Review
2003
Review
2003
The CD95 type I/type II model.
Review
2000
Review
2000
Mitochondrion as a novel target of anticancer chemotherapy.
Mitochondrial membrane permeabilization is a critical event in the process leading to physiologic or chemotherapy-induced… 
Highly Cited
1999
Highly Cited
1999
Control of apoptosis by Rel/NF-κB transcription factors
Apoptosis is a physiological process critical for organ development, tissue homeostasis, and elimination of defective or… 
Review
1999
Review
1999
Apoptosis inducing factor (AIF): a phylogenetically old, caspase-independent effector of cell death
Although much emphasis has been laid on the role of caspase in cell death, recent data indicate that, in many instances… 
Highly Cited
1999
Highly Cited
1999
Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.
There is growing evidence that the p53 tumor suppressor protein not only can function to activate gene transcription but also to… 
Highly Cited
1998
Highly Cited
1998
Inhibition of growth and induction of apoptosis in human cancer cell lines by tea polyphenols.
In order to study the biological activities of tea preparations and purified tea polyphenols, their growth inhibitory effects… 
Highly Cited
1997
Highly Cited
1997
Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells.
BACKGROUND AND PURPOSE The polyphenolic compounds present in green tea show cancer chemopreventive effects in many animal tumor… 
Highly Cited
1995
Highly Cited
1995
Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis
As a result of bioassay–guided fractionation, betulinic acid, a pentacyclic triterpene, was identified as a melanoma–specific… 
Highly Cited
1989
Highly Cited
1989
Monoclonal antibody-mediated tumor regression by induction of apoptosis.
To characterize cell surface molecules involved in control of growth of malignant lymphocytes, monoclonal antibodies were raised… 
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