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Positive Regulation of Apoptosis
Known as:
up-regulation of apoptosis
, Induction of Apoptosis
, upregulation of apoptosis
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Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process. [GOC:jl, GOC:mtg_apoptosis]
National Institutes of Health
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Related topics
Related topics
50 relations
2-methoxyestradiol (nanocrystal colloidal dispersion)
ANP32B wt Allele
ARHGEF7 wt Allele
Apoptotic BCL2L1-Antisense Long Non-Coding RNA, human
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Narrower (1)
activation of apoptosis
Broader (1)
biological control
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Multidomain Bcl-2 homolog Bax but not Bak mediates synergistic induction of apoptosis by TRAIL and 5-FU through the mitochondrial apoptosis pathway
C. Haefen
,
B. Gillissen
,
+6 authors
P. Daniel
Oncogene
2004
Corpus ID: 12802229
The death ligand TRAIL synergizes with DNA-damaging therapies such as chemotherapeutic drugs or ionizing irradiation. Here, we…
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Highly Cited
2003
Highly Cited
2003
Gene expression profiling of multiple myeloma reveals molecular portraits in relation to the pathogenesis of the disease.
F. Magrangeas
,
V. Nasser
,
+10 authors
S. Minvielle
Blood
2003
Corpus ID: 35495404
Although multiple myeloma (MM) is a unique entity, a marked heterogeneity is actually observed among the patients, which has been…
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Highly Cited
2003
Highly Cited
2003
Effects of Brassica vegetable juice on the induction of apoptosis and aberrant crypt foci in rat colonic mucosal crypts in vivo.
Tracy K. Smith
,
R. Mithen
,
I. Johnson
Carcinogenesis
2003
Corpus ID: 26953389
Glucosinolates are sulfur-containing glycosides found in the Brassica vegetables. Their breakdown products include…
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Highly Cited
2002
Highly Cited
2002
Cyclooxygenase-2 overexpression inhibits death receptor 5 expression and confers resistance to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human colon cancer cells.
Ximing Tang
,
Yunjie Sun
,
E. Half
,
M. Kuo
,
F. Sinicrope
Cancer Research
2002
Corpus ID: 27316949
The inducible cyclooxygenase-2 (COX-2) gene regulates prostaglandin biosynthesis,is up-regulated in colorectal cancers, and can…
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Highly Cited
2001
Highly Cited
2001
Partial Activation and Induction of Apoptosis in CD4+ and CD8+ T Lymphocytes by Conformationally Authentic Noninfectious Human Immunodeficiency Virus Type 1
M. Esser
,
J. Bess
,
+5 authors
J. Lifson
Journal of Virology
2001
Corpus ID: 6349378
ABSTRACT Increased levels of apoptosis are seen in human immunodeficiency virus (HIV) infection, and this has been proposed as an…
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Highly Cited
2000
Highly Cited
2000
Growth inhibition and synergistic induction of apoptosis by zoledronate and dexamethasone in human myeloma cell lines
P. Tassone
,
S. Forciniti
,
+5 authors
Salvatore Venuta
Leukemia
2000
Corpus ID: 6173876
Bisphosphonates (BPs) are commonly used in the treatment of myeloma-associated osteolytic lesions. Recent reports have suggested…
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Highly Cited
1999
Highly Cited
1999
Caspase involvement in the induction of apoptosis by the environmental toxicants tributyltin and triphenyltin.
H. Stridh
,
S. Orrenius
,
Mark B. Hampton
Toxicology and Applied Pharmacology
1999
Corpus ID: 23669449
Organotin compounds such as tributyltin (TBT) and triphenyltin (TPT) can kill target cells by triggering apoptosis. The mechanism…
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Highly Cited
1998
Highly Cited
1998
Regulation of RARβ expression by RAR‐ and RXR‐selective retinoids in human lung cancer cell lines: Effect on growth inhibition and apoptosis induction
Yin Li
,
M. Dawson
,
+4 authors
Xiao-kun Zhang
International Journal of Cancer
1998
Corpus ID: 12773100
Retinoids regulate the growth and differentiation of human tracheobronchial epithelial cells. In this study, we investigated the…
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Highly Cited
1997
Highly Cited
1997
Comparison of ribosome-inactivating proteins in the induction of apoptosis.
J. Williams
,
N. Lea
,
J. Lord
,
L. Roberts
,
D. Milford
,
C. Taylor
Toxicology Letters
1997
Corpus ID: 30017339
Highly Cited
1993
Highly Cited
1993
Early and selective induction of apoptosis in human leukemic cells by the alkyl-lysophospholipid ET-18-OCH3.
F. Mollinedo
,
R. Martínez-Dalmau
,
Manuel Modolell
Biochemical and Biophysical Research…
1993
Corpus ID: 19514037
We have found that the alkyl-lysophospholipid 1-octadecyl-2-methyl-rac-glycero-3-phosphocholine (ET-18-OCH3) was able to induce…
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