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Positive Regulation of Apoptosis

Known as: up-regulation of apoptosis, Induction of Apoptosis, upregulation of apoptosis 
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process. [GOC:jl, GOC:mtg_apoptosis]
National Institutes of Health

Related topics

Related topics

50 relations
2-methoxyestradiol (nanocrystal colloidal dispersion)ANP32B wt AlleleARHGEF7 wt AlleleApoptotic BCL2L1-Antisense Long Non-Coding RNA, human

Narrower (1)

activation of apoptosis

Broader (1)

biological control

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Multidomain Bcl-2 homolog Bax but not Bak mediates synergistic induction of apoptosis by TRAIL and 5-FU through the mitochondrial apoptosis pathway
The death ligand TRAIL synergizes with DNA-damaging therapies such as chemotherapeutic drugs or ionizing irradiation. Here, we… 
Highly Cited
2004
Highly Cited
2004
Bax Mediates the Apoptosis-Sensitizing Effect of Maspin
Maspin, a serine protease inhibitor (serpin), can suppress tumor growth and metastasis in vivo and tumor cell motility and… 
Highly Cited
2003
Highly Cited
2003
Gene expression profiling of multiple myeloma reveals molecular portraits in relation to the pathogenesis of the disease.
Although multiple myeloma (MM) is a unique entity, a marked heterogeneity is actually observed among the patients, which has been… 
Highly Cited
2003
Highly Cited
2003
Caspase-dependent Alterations of Ca2+ Signaling in the Induction of Apoptosis by Hepatitis B Virus X Protein*
The hepatitis B virus X protein (HBx) is a multifunctional protein, acting on different targets (e.g. transcription factors… 
Highly Cited
2002
Highly Cited
2002
Cyclooxygenase-2 overexpression inhibits death receptor 5 expression and confers resistance to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human colon cancer cells.
The inducible cyclooxygenase-2 (COX-2) gene regulates prostaglandin biosynthesis,is up-regulated in colorectal cancers, and can… 
Highly Cited
2001
Highly Cited
2001
Partial Activation and Induction of Apoptosis in CD4+ and CD8+ T Lymphocytes by Conformationally Authentic Noninfectious Human Immunodeficiency Virus Type 1
ABSTRACT Increased levels of apoptosis are seen in human immunodeficiency virus (HIV) infection, and this has been proposed as an… 
Highly Cited
2000
Highly Cited
2000
Growth inhibition and synergistic induction of apoptosis by zoledronate and dexamethasone in human myeloma cell lines
Bisphosphonates (BPs) are commonly used in the treatment of myeloma-associated osteolytic lesions. Recent reports have suggested… 
Highly Cited
2000
Highly Cited
2000
Tea catechins and related polyphenols as anti-cancer agents.
Epigallocatechin gallate (EGCg) and theaflavins, a major constituent of green tea infusion and the constituents of black tea… 
Highly Cited
1998
Highly Cited
1998
Essential role of p53 in phenethyl isothiocyanate-induced apoptosis.
Phenethyl isothiocyanate (PEITC) is a natural product that is among the most effective cancer chemopreventive agents known… 
Highly Cited
1998
Highly Cited
1998
Regulation of RARβ expression by RAR‐ and RXR‐selective retinoids in human lung cancer cell lines: Effect on growth inhibition and apoptosis induction
Retinoids regulate the growth and differentiation of human tracheobronchial epithelial cells. In this study, we investigated the… 
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