Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 227,741,318 papers from all fields of science
Search
Sign In
Create Free Account
Tumor Suppressor ARF, human
Known as:
CDKN2A-p14ARF
, p19(ARF)
, p14(ARF)
Expand
Tumor suppressor ARF (173 aa, ~18 kDa) is encoded by the human CDKN2A gene. This protein is involved in cell cycle arrest.
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
23 relations
CDKN2A gene
CDKN2A wt Allele
CTCF Pathway
Cell Cycle Control
Expand
Broader (2)
Cyclin-Dependent Kinase Inhibitor Proteins
Cyclin-Dependent Kinase Inhibitor p16
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Regulation of the p14ARF promoter by DNA methylation
Vinay Badal
,
S. Menéndez
,
D. Coomber
,
D. Lane
Cell Cycle
2008
Corpus ID: 11923897
The INK4a/ARF locus encodes p14ARF which plays an important role in the p53 pathway. Interestingly, methylation of the INK4a/ARF…
Expand
Highly Cited
2007
Highly Cited
2007
The autophagic inducer smARF interacts with and is stabilized by the mitochondrial p32 protein
S. Reef
,
O. Shifman
,
M. Oren
,
A. Kimchi
Oncogene
2007
Corpus ID: 24201629
The alternative reading frame (ARF) mRNA encodes two pro-death proteins, the nucleolar p19ARF and a shorter mitochondrial isoform…
Expand
2007
2007
Expression of the alternative reading frame protein of Hepatitis C virus induces cytokines involved in hepatic injuries.
Marc Fiorucci
,
S. Boulant
,
+5 authors
C. Bain
Journal of General Virology
2007
Corpus ID: 1941530
Hepatitis C virus (HCV) Core has been implicated in immune-mediated mechanisms associated with the development of chronic hepatic…
Expand
2005
2005
p14ARF Induces G2 Cell Cycle Arrest in p53- and p21-deficient Cells by Down-regulating p34cdc2 Kinase Activity*
G. Normand
,
P. Hemmati
,
+6 authors
P. Daniel
Journal of Biological Chemistry
2005
Corpus ID: 25575050
The human INK4a gene locus encodes two structurally unrelated tumor suppressor proteins, p16INK4a and p14ARF. Although primarily…
Expand
Highly Cited
2003
Highly Cited
2003
Gene Fusion and Overlapping Reading Frames in the Mammalian Genes for 4E-BP3 and MASK*
F. Poulin
,
Andrea Brueschke
,
N. Sonenberg
Journal of Biological Chemistry
2003
Corpus ID: 25715473
4E-BP3 is a member of the eukaryotic initiation factor (eIF) 4F-binding protein family of translational repressors. eIF4E-binding…
Expand
Highly Cited
2002
Highly Cited
2002
Human tumor suppressor ARF impedes S-phase progression independent of p53.
W. Yarbrough
,
M. Bessho
,
A. Zanation
,
J. Bisi
,
Y. Xiong
Cancer Research
2002
Corpus ID: 15725670
Using alternative reading frames, the human ARF-INK4a locus encodes two unrelated proteins that both function in tumor…
Expand
2002
2002
A Major Functional Difference between the Mouse and Human ARF Tumor Suppressor Proteins*
R. Wadhwa
,
T. Sugihara
,
M. Hasan
,
K. Taira
,
R. Reddel
,
S. Kaul
Journal of Biological Chemistry
2002
Corpus ID: 31023016
Suppression of tumorigenesis is considerably more stringent in the human than in the much shorter lived mouse species, and the…
Expand
2001
2001
The p14ARF tumor suppressor protein facilitates nucleolar sequestration of hypoxia-inducible factor-1alpha (HIF-1alpha ) and inhibits HIF-1-mediated transcription.
K. Fátyol
,
A. Szalay
Journal of Biological Chemistry
2001
Corpus ID: 27249575
Oncogenic alterations can influence tumor cell survival partly by affecting the activity of the hypoxia-inducible factor-1 (HIF-1…
Expand
2001
2001
c-Myc-mediated Regulation of Telomerase Activity Is Disabled in Immortalized Cells*
R. Drissi
,
F. Zindy
,
M. Roussel
,
J. Cleveland
Journal of Biological Chemistry
2001
Corpus ID: 22891276
Myc overexpression is a hallmark of human cancer and promotes transformation by facilitating immortalization. This function has…
Expand
Highly Cited
1992
Highly Cited
1992
Two unusual forms of human immunoglobulin E encoded by alternative RNA splicing of epsilon heavy chain membrane exons
K. Zhang
,
A. Saxon
,
E. E. Max
Journal of Experimental Medicine
1992
Corpus ID: 9660347
We present evidence for RNA transcripts encoding two forms of human epsilon immunoglobulin (Ig) heavy chain that differ…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
(opens in a new tab)
,
Terms of Service
(opens in a new tab)
, and
Dataset License
(opens in a new tab)
ACCEPT & CONTINUE