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Cyclin-Dependent Kinase Inhibitor Proteins

Known as: CDKI Protein, Cyclin-Dependent Kinase Inhibitor Proteins [Chemical/Ingredient], Cyclin Dependent Kinase Inhibitor Proteins 
A group of cell cycle proteins that negatively regulate the activity of CYCLIN/CYCLIN-DEPENDENT KINASE complexes. They inhibit CELL CYCLE progression… Expand
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
Mutations in the MEN1 gene are associated with the multiple endocrine neoplasia syndrome type 1 (MEN1), which is characterized by… Expand
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Highly Cited
2004
Highly Cited
2004
Prostate cancer is the second leading cause of cancer-related deaths in males in the United States. This warrants the development… Expand
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Review
2003
Review
2003
The PI3K/Akt signal transduction cascade has been investigated extensively for its roles in oncogenic transformation. Initial… Expand
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Highly Cited
2001
Highly Cited
2001
Cyclin-dependent kinase inhibitors, such as the mammalian p27Kip1 protein, regulate correct cell cycle progression and the… Expand
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Highly Cited
1999
Highly Cited
1999
Molecular mechanisms coupling growth arrest and cell differentiation were examined during adipogenesis. Data are presented that… Expand
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Highly Cited
1998
Highly Cited
1998
It has been suggested that overexpression of the Bcl-2 oncoprotein in human cancer cells contributes to their resistance to… Expand
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Highly Cited
1996
Highly Cited
1996
Understanding how cyclin-cdk complexes recognize their substrates is a central problem in cell cycle biology. We identified an… Expand
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Highly Cited
1996
Highly Cited
1996
Alterations of various components of the cell cycle regulatory machinery that controls the progression of cells from a quiescent… Expand
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Highly Cited
1994
Highly Cited
1994
When yeast cells reach a critical size, they initiate bud formation, spindle pole body duplication, and DNA replication almost… Expand
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Highly Cited
1994
Highly Cited
1994
In normal human fibroblast cells, the primary cell cycle regulators, the cyclin-dependent kinases (CDKs), exist predominantly in… Expand
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