Skip to search formSkip to main contentSkip to account menu

CDKN2A gene

Known as: p16 gene, TP16, p16INK4 Genes 
Tumor suppressor genes located on human chromosome 9 in the region 9p21. This gene is either deleted or mutated in a wide range of malignancies… 
National Institutes of Health

Related topics

Related topics

47 relations
Advanced Peritoneal Malignant MesotheliomaBeckwith-Wiedemann SyndromeBiphasic MesotheliomaCDKN2A Gene Mutation

Narrower (1)

CDKN2A wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2004
Review
2004
Unraveling Human Tumor Suppressor Pathways: A Tale of the INK4A Locus
Research on tumor suppressors has for a long time run on two tracks: analysis of the mutations found in human tumor material, and… 
2003
2003
Limitations of the widely used GAM42a and BET42a probes targeting bacteria in the Gammaproteobacteria radiation.
The 23S rRNA-targeted probes GAM42a and BET42a provided equivocal results with the uncultured gammaproteobacterium 'Candidatus… 
2000
2000
Absence of germline p16 INK4a alterations in p53 wild type Li-Fraumeni syndrome families
Editor—The Li-Fraumeni syndrome (LFS) is a rare familial cancer syndrome that predisposes gene carriers to the development of… 
2000
2000
Homozygous Deletions of the p 16 Tumor-Suppressor Gene Are Associated With Lymphoid Transformation of Chronic Myeloid Leukemia
The p16 gene, also referred to as MTS1, INK4, CDKQI, or CDKN2, at chromosome 9p21 has recently been described as a tumor… 
Review
1997
Review
1997
Screening for CDKN2A mutations in hereditary melanoma.
Cutaneous malignant melanoma (CMM) is a potentially fatal form of skin cancer whose etiology is heterogeneous and complex… 
1995
1995
Loh and mutation analysis of CDKN2 in primary human ovarian cancers
The CDKN2 gene encodes a cell cycle regulatory protein and is located on chromosome 9p21, a region deleted in a wide variety of… 
1987
1987
Expression of HTLV-I in serum of HTLV-I-related subjects and the early detection of overt ATL in HTLV-I carriers.
Monoclonal antibodies against human T cell leukemia virus type I (HTLV-I) p24 and p19 were produced and employed in the in vivo… 
1984
1984
The ribosomal RNA genes from chloroplasts of mustard (Sinapis alba L.): mapping and sequencing of the leader region
SummaryThe genes coding for rRNAs from mustard chloroplasts were mapped within the inverted repeat regions of intact ctDNA and on… 
1983
1983
Replication origin region of Bacillus subtilis chromosome contains two rRNA operons
The first replicating DNA fragment (BamHI-7) of the Bacillus subtilis chromosome contains two promoters for a rRNA operon. A map… 
Highly Cited
1980
Highly Cited
1980
Some characteristics of processing sites in ribosomal precursor RNA of yeast
The DNA sequences of the intergenic region between the 17S and 5.8S rRNA genes of the ribosomal RNA operon in yeast has been…