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Transcription Initiation

Known as: Initiation 
Transcription Initiation involves RNA polymerase (and usually other factors) binding at a specific gene promoter DNA site followed by local DNA… 
National Institutes of Health

Related topics

Related topics

50 relations
BRF1 protein, humanBRF2 geneCCNC geneCCNC wt Allele

Papers overview

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Highly Cited
2005
Highly Cited
2005
The initiation of liver development is dependent on Foxa transcription factors
The specification of the vertebrate liver is thought to occur in a two-step process, beginning with the establishment of… 
Review
2004
Review
2004
Eukaryotic MCM Proteins: Beyond Replication Initiation
SUMMARY The minichromosome maintenance (or MCM) protein family is composed of six related proteins that are conserved in all… 
Highly Cited
2002
Highly Cited
2002
Structural Basis of Transcription Initiation: An RNA Polymerase Holoenzyme-DNA Complex
The crystal structure of Thermus aquaticus RNA polymerase holoenzyme (α2ββ′ωσA) complexed with a fork-junction promoter DNA… 
Highly Cited
2000
Highly Cited
2000
Efficient initiation of HCV RNA replication in cell culture.
Hepatitis C virus (HCV) infection is a global health problem affecting an estimated 170 million individuals worldwide. We report… 
Review
1991
Review
1991
Structural features in eukaryotic mRNAs that modulate the initiation of translation.
Highly Cited
1990
Highly Cited
1990
Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon
Highly Cited
1982
Highly Cited
1982
The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection.
We characterized the transcriptional activity of the long terminal repeat (LTR) of Rous sarcoma virus by constructing a… 
Highly Cited
1981
Highly Cited
1981
Possible role of flanking nucleotides in recognition of the AUG initiator codon by eukaryotic ribosomes.
Sequences flanking the initiator codon in eukaryotic mRNAs are not random. Out of 153 messages examined, 151 have either a purine… 
Highly Cited
1975
Highly Cited
1975
Transfer to proteins across membranes. II. Reconstitution of functional rough microsomes from heterologous components
The data presented in this paper demonstrate that native small ribosomal subunits from reticulocytes (containing initiation… 
Highly Cited
1971
Highly Cited
1971
Research Communication
The crystal structures of the full-length human eukaryotic initiation factor (eIF) 4E complexed with two mRNA cap analogues [7… 
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