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Transcription Initiation

Known as: Initiation 
Transcription Initiation involves RNA polymerase (and usually other factors) binding at a specific gene promoter DNA site followed by local DNA… 
National Institutes of Health

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Related topics

50 relations
BRF1 protein, humanBRF2 geneCCNC geneCCNC wt Allele
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Papers overview

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Review
2011
Review
2011
CpG islands and the regulation of transcription.
Vertebrate CpG islands (CGIs) are short interspersed DNA sequences that deviate significantly from the average genomic pattern by… 
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Highly Cited
2009
Highly Cited
2009
Prodigal: prokaryotic gene recognition and translation initiation site identification
BackgroundThe quality of automated gene prediction in microbial organisms has improved steadily over the past decade, but there… 
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Highly Cited
2007
Highly Cited
2007
A Chromatin Landmark and Transcription Initiation at Most Promoters in Human Cells
We describe the results of a genome-wide analysis of human cells that suggests that most protein-coding genes, including most… 
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Review
2007
Review
2007
The Role of Chromatin during Transcription
Chromatin structure imposes significant obstacles on all aspects of transcription that are mediated by RNA polymerase II. The… 
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Highly Cited
2006
Highly Cited
2006
Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock*
Objective:To determine the prevalence and impact on mortality of delays in initiation of effective antimicrobial therapy from… 
Review
2004
Review
2004
The regulation of bacterial transcription initiation
Bacteria use their genetic material with great effectiveness to make the right products in the correct amounts at the appropriate… 
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Highly Cited
2003
Highly Cited
2003
The nuclear RNase III Drosha initiates microRNA processing
Hundreds of small RNAs of ∼22 nucleotides, collectively named microRNAs (miRNAs), have been discovered recently in animals and… 
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Highly Cited
2001
Highly Cited
2001
Role for a bidentate ribonuclease in the initiation step of RNA interference
RNA interference (RNAi) is the mechanism through which double-stranded RNAs silence cognate genes. In plants, this can occur at… 
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Review
1986
Review
1986
Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes
By analyzing the effects of single base substitutions around the ATG initiator codon in a cloned preproinsulin gene, I have… 
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Highly Cited
1983
Highly Cited
1983
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei.
We have developed a procedure for preparing extracts from nuclei of human tissue culture cells that directs accurate… 
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