FAQ

Transcription Initiation

Known as: Initiation 
Transcription Initiation involves RNA polymerase (and usually other factors) binding at a specific gene promoter DNA site followed by local DNA… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1985-2017
05101519852017

Related topics

Related topics

50 relations
BDP1 geneBDP1 protein, humanBRF1 protein, humanBRF2 wt Allele
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Related mentions per year

Related mentions per year

1939-2018
19401960198020002020
Transcription Initiation
Gene Expression
Transcription, Genetic
HMGB1 Protein
HMGB1 gene
NR5A2 gene

Papers overview

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2014
2014
Pol III Promoters to Express Small RNAs: Delineation of Transcription Initiation
Pol III promoters such as U6 are commonly used to express small RNAs, including small interfering RNA, short hairpin RNA, and… (More)
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2013
2013
Genomic Organization of Human Transcription Initiation Complexes
A repertoire of transcription initiation factors engage the core promoter of mRNA genes to recruit RNA polymerase (Pol) II to… (More)
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2012
2012
Mechanism of Transcription Initiation at an Activator-Dependent Promoter Defined by Single-Molecule Observation
Understanding the pathway and kinetic mechanisms of transcription initiation is essential for quantitative understanding of gene… (More)
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2011
2011
The Initiation Factor TFE and the Elongation Factor Spt4/5 Compete for the RNAP Clamp during Transcription Initiation and Elongation
TFIIE and the archaeal homolog TFE enhance DNA strand separation of eukaryotic RNAPII and the archaeal RNAP during transcription… (More)
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2011
2011
Transcription Initiation Patterns Indicate Divergent Strategies for Gene Regulation at the Chromatin Level
The application of deep sequencing to map 5' capped transcripts has confirmed the existence of at least two distinct promoter… (More)
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2010
2010
Phosphorylation of TFIIB Links Transcription Initiation and Termination
The general transcription factor TFIIB plays a central role in preinitiation complex (PIC) assembly and the recruitment of RNA… (More)
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Highly Cited
2009
Highly Cited
2009
Transcription Initiation Activity Sets Replication Origin Efficiency in Mammalian Cells
Genomic mapping of DNA replication origins (ORIs) in mammals provides a powerful means for understanding the regulatory… (More)
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2009
2009
Differentiation Driven Changes in the Dynamic Organization of Basal Transcription Initiation
Studies based on cell-free systems and on in vitro-cultured living cells support the concept that many cellular processes, such… (More)
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Highly Cited
2007
Highly Cited
2007
A Chromatin Landmark and Transcription Initiation at Most Promoters in Human Cells
We describe the results of a genome-wide analysis of human cells that suggests that most protein-coding genes, including most… (More)
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Highly Cited
2004
Highly Cited
2004
DksA A Critical Component of the Transcription Initiation Machinery that Potentiates the Regulation of rRNA Promoters by ppGpp and the Initiating NTP
Ribosomal RNA (rRNA) transcription is regulated primarily at the level of initiation from rRNA promoters. The unusual kinetic… (More)
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