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BRF1 protein, human

Known as: B-Related Factor 1, TBP-Associated Factor, RNA Polymerase III, 90-kD, TFIIIB90 
Transcription factor IIIB 90 kDa subunit (677 aa, ~74 kDa) is encoded by the human BRF1 gene. This protein plays a role in the transcription of both… 
National Institutes of Health

Related topics

Related topics

17 relations
BDP1 geneBDP1 protein, humanBRF1 geneBRF1 wt Allele

Broader (1)

TATA-Binding Protein Associated Factors

Papers overview

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Review
2012
Review
2012
Generating global Leaf Area Index from Landsat: Algorithm formulation and demonstration
Highly Cited
2008
Highly Cited
2008
A coupled 1-D atmosphere and 3-D canopy radiative transfer model for canopy reflectance, light environment, and photosynthesis simulation in a heterogeneous landscape
Highly Cited
2008
Highly Cited
2008
Enhanced RNA Polymerase III-dependent Transcription Is Required for Oncogenic Transformation*♦
RNA polymerase (pol) III transcription, responsible for the synthesis of various stable RNAs, including 5 S rRNAs and tRNAs, is… 
Highly Cited
2008
Highly Cited
2008
The AU-rich element mRNA decay-promoting activity of BRF1 is regulated by mitogen-activated protein kinase-activated protein kinase 2.
Regulated mRNA decay is a highly important process for the tight control of gene expression. Inherently unstable mRNAs contain AU… 
Highly Cited
2007
Highly Cited
2007
TTP and BRF proteins nucleate processing body formation to silence mRNAs with AU-rich elements.
In mammalian cells, mRNAs with AU-rich elements (AREs) are targeted for translational silencing and rapid degradation. Here we… 
Highly Cited
2006
Highly Cited
2006
BRF1 Protein Turnover and mRNA Decay Activity Are Regulated by Protein Kinase B at the Same Phosphorylation Sites
ABSTRACT BRF1 posttranscriptionally regulates mRNA levels by targeting ARE-bearing transcripts to the decay machinery. We… 
Highly Cited
2004
Highly Cited
2004
Roles of AUF1 isoforms, HuR and BRF1 in ARE-dependent mRNA turnover studied by RNA interference.
HT1080 cells stably expressing green fluorescent protein (GFP) linked to a 3' terminal AU-rich element (ARE) proved to be a… 
Highly Cited
2000
Highly Cited
2000
Different human TFIIIB activities direct RNA polymerase III transcription from TATA-containing and TATA-less promoters.
Transcription initiation at RNA polymerase III promoters requires transcription factor IIIB (TFIIIB), an activity that binds to… 
Highly Cited
2000
Highly Cited
2000
A TRF1:BRF Complex Directs Drosophila RNA Polymerase III Transcription
Highly Cited
1995
Highly Cited
1995
Structure and function of a human transcription factor TFIIIB subunit that is evolutionarily conserved and contains both TFIIB- and high-mobility-group protein 2-related domains.
Transcription factor TFIIIB plays a central role in transcription initiation by RNA polymerase III on genes encoding tRNA, 5S… 
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