BRF2 gene

Known as: TRANSCRIPTION FACTOR IIB-RELATED FACTOR, BRF2 SUBUNIT OF RNA POLYMERASE III TRANSCRIPTION INITIATION FACTOR, BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit 
This gene plays a role in transcriptional initiation and has been purported to play an oncogenic role in breast cancer development.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2000-2018
02420002018

Papers overview

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2015
2015
BRF2 is a transcription factor required for synthesis of a small group of non-coding RNAs by RNA polymerase III. Overexpression… (More)
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2015
2015
TFIIB-related factor 2 (Brf2) is a member of the family of TFIIB-like core transcription factors. Brf2 recruits RNA polymerase… (More)
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2014
2014
BACKGROUND We aimed to investigate prevalence and prognostic role of SOX2, PIK3CA, FGFR1 and BRF2 gene gain in patients with… (More)
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2013
2013
Studies have shown that genetic activation of TFIIB-related factor 2 (BRF2) represents a unique mechanism of tumorigenesis… (More)
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2012
2012
SNAP(c) is one of a few basal transcription factors used by both RNA polymerase (pol) II and pol III. To define the set of active… (More)
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Highly Cited
2010
Highly Cited
2010
Genome-wide occupancy profiles of five components of the RNA polymerase III (Pol III) machinery in human cells identified the… (More)
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2010
2010
BACKGROUND Traditionally, non-small cell lung cancer is treated as a single disease entity in terms of systemic therapy. Emerging… (More)
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2009
2009
RNA polymerase III (RNA pol III) transcribes structural RNAs involved in RNA processing (U6 snRNA) and translation (tRNA… (More)
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2008
2008
RNA polymerase (pol) III transcription is specifically elevated in a variety of cancers and is a target of regulation by a… (More)
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2001
2001
The human snRNA genes transcribed by RNA polymerase II (pol II) and III (pol III) have different core promoter elements. Both… (More)
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