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Thromboxanes

Known as: Thromboxane, Thromboxanes [Chemical/Ingredient] 
Physiologically active compounds found in many organs of the body. They are formed in vivo from the prostaglandin endoperoxides and cause platelet… 
National Institutes of Health

Related topics

Related topics

21 relations
11-Dehydro thromboxane beta 2:MCnc:Pt:Urine:Qn11-Dehydro thromboxane beta 2:MRat:24H:Urine:QnIn BloodProcess of secretion

Broader (3)

AutacoidsEicosanoidsFatty Acids

Narrower (4)

Thromboxane A2Thromboxane B2thromboxane A3thromboxane B3

Papers overview

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Highly Cited
1997
Highly Cited
1997
S 18886, a new thromboxane (TP)-receptor antagonist is the active isomer of S 18204 in all species, except in the guinea-pig.
Thromboxane (TXA2) causes platelet aggregation, vasoconstriction and cell proliferation through the activation of specific cell… 
1990
1990
R68070, a combined thromboxane/endoperoxide receptor antagonist and thromboxane synthase inhibitor, inhibits human platelet activation in vitro and in vivo: a comparison with aspirin
We have investigated the effects of R68070 on platelet function in vitro and in vivo. The drug inhibits U46619induced aggregation… 
Review
1987
Review
1987
A pharmacological approach to thromboxane receptor antagonism.
Thromboxane A2 (TxA2) appears to be an important mediator of ischemia and hypoxia. Despite its short half-life and the fact that… 
1983
1983
Recent progress in the role of platelets in occlusive vascular disease.
Abstract not available. 
1982
1982
Roles of Endogenous Prostacyclin and Thromboxane A2 in the Ischemic Canine Heart
Summary The ability of the ischemic heart to release prostacyclin (PGI2) and thromboxane A2 (TXA2) was studied, together with the… 
Highly Cited
1981
Highly Cited
1981
Prostacyclin and thromboxane A2 formation in response to adrenergic stimulation in humans: a mechanism for local control of vascular response to sympathetic activation?
Prostacyclin (PGI2) and thromboxane A2 (TxA2), antiaggregating and aggregating agents, may be involved in the control of local… 
1981
1981
Leukocytes, platelets, and thromboxane A2 in endotoxin-induced lung injury.
The relationship of leukocytes, platelets, and thromboxane A2 (TxA2) to endotoxin-induced lung injury was studied by use of… 
Highly Cited
1979
Highly Cited
1979
Thromboxane synthesis and platelet protein release during simulated extracorporeal circulation.
Platelet secretion induced by certain soluble aggregating agents is associated with thromboxane formation. Activation of… 
Highly Cited
1978
Highly Cited
1978
Actions of prostaglandins on isolated perfused cat coronary arteries.
Effects of prostaglandins on coronary arterial smooth muscle were studied in isolated perfused cat coronary arteries. This… 
Highly Cited
1977
Highly Cited
1977
Prostaglandin endoperoxides and thromboxane A2 can induce platelet aggregation in the absence of secretion
PLATELET aggregation and secretion are widely studied not only because they are believed to reflect the major in vivo platelet…