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Thromboxane B2

Known as: Thromboxa-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, (5Z,9alpha,13E,15S)-, B2, Thromboxane, Thromboxane B2 [Chemical/Ingredient] 
An eicosanoid and biologically inactive metabolite of thromboxane A2. Thromboxane B2 is released during anaphylaxis. As thromboxane A2 has a short… Expand
National Institutes of Health

Related topics

Related topics

20 relations
11-Dehydro thromboxane beta 2:MCnc:Pt:Urine:Qn11-Dehydro thromboxane beta 2:MRat:24H:Urine:QnIn BloodProcess of secretion
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Narrower (6)

11-dehydro-2,3-dinor-thromboxane B211-dehydro-2,3-dinorthromboxane B311-dehydro-thromboxane B211-dehydrothromboxane B3
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Broader (1)

Thromboxanes

Papers overview

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Highly Cited
2002
Highly Cited
2002
Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events.
BACKGROUND We studied whether aspirin resistance, defined as failure of suppression of thromboxane generation, increases the risk… Expand
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Highly Cited
1998
Highly Cited
1998
Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.
Apoptosis in vivo is followed almost inevitably by rapid uptake into adjacent phagocytic cells, a critical process in tissue… Expand
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Highly Cited
1996
Highly Cited
1996
Modulation of oxidant stress in vivo in chronic cigarette smokers.
BACKGROUND Free radical-induced oxidative damage is thought to be involved in the pathogenesis of diseases associated with… Expand
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Highly Cited
1995
Highly Cited
1995
Fixed oil of Nigella sativa and derived thymoquinone inhibit eicosanoid generation in leukocytes and membrane lipid peroxidation.
Samples of the expressed fixed oil from different sources of Nigella sativa seeds were examined by thin-layer and gas… Expand
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Highly Cited
1992
Highly Cited
1992
An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension.
BACKGROUND Constriction of small pulmonary arteries and arterioles and focal vascular injury are features of pulmonary… Expand
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Highly Cited
1990
Highly Cited
1990
Thromboxane biosynthesis and platelet function in type II diabetes mellitus.
It has been suggested that platelet hyperreactivity in patients with diabetes mellitus is associated with increased platelet… Expand
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Highly Cited
1983
Highly Cited
1983
The biological significance of platelet volume: its relationship to bleeding time, platelet thromboxane B2 production and megakaryocyte nuclear DNA concentration.
Bleeding time, platelet thromboxane B2 production and megakaryocyte nuclear DNA concentration were measured in rabbits recovering… Expand
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Highly Cited
1983
Highly Cited
1983
Endogenous biosynthesis of prostacyclin and thromboxane and platelet function during chronic administration of aspirin in man.
To assess the pharmacologic effects of aspirin on endogenous prostacyclin and thromboxane biosynthesis, 2,3-dinor-6-keto PGF1… Expand
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Highly Cited
1980
Highly Cited
1980
Low dose aspirin and inhibition of thromboxane B2 production in healthy subjects.
Abstract We studied the time- and dose-dependence of the inhibitory effect of oral aspirin on platelet production of thromboxane… Expand
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Highly Cited
1975
Highly Cited
1975
Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides.
An unstable [t1/2 at 37 degrees = 32 +/- 2 (SD) sec] intermediate, thromboxane A2, was detected in the conversion of… Expand
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