FAQ

Thromboxane B2

Known as: B2, Thromboxane, Thromboxane B2 [Chemical/Ingredient], (5Z,13E,15S)-9alpha,11,15-Trihydroxythromboxa-5,13-Dien-1-Oic Acid 
An eicosanoid and biologically inactive metabolite of thromboxane A2. Thromboxane B2 is released during anaphylaxis. As thromboxane A2 has a short… (More)

Topic mentions per year

Topic mentions per year

1975-2017
020040019752017

Related topics

Related topics

16 relations

Narrower (4)

11-dehydro-2,3-dinorthromboxane B311-dehydro-thromboxane B211-dehydrothromboxane B32,3-dinor-thromboxane B2
In BloodProcess of secretionadministration & dosageagonists
(More)

Broader (1)

Thromboxanes

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Thromboxane B2
physiological aspects
agonists
Thromboxanes
chemical synthesis
standards characteristics

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
Aspirin-resistant thromboxane biosynthesis and the risk of myocardial infarction, stroke, or cardiovascular death in patients at high risk for cardiovascular events.
BACKGROUND We studied whether aspirin resistance, defined as failure of suppression of thromboxane generation, increases the risk… (More)
  • table 1
  • table 2
  • table 3
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.
Apoptosis in vivo is followed almost inevitably by rapid uptake into adjacent phagocytic cells, a critical process in tissue… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1992
Highly Cited
1992
An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension.
BACKGROUND Constriction of small pulmonary arteries and arterioles and focal vascular injury are features of pulmonary… (More)
Is this relevant?
Highly Cited
1992
Highly Cited
1992
Phagocytosis of apoptotic neutrophils does not induce macrophage release of thromboxane B2.
Senescent human neutrophils undergo programmed cell death (apoptosis), leading to their recognition and phagocytosis by mature… (More)
Is this relevant?
Highly Cited
1990
Highly Cited
1990
Thromboxane biosynthesis and platelet function in type II diabetes mellitus.
It has been suggested that platelet hyperreactivity in patients with diabetes mellitus is associated with increased platelet… (More)
Is this relevant?
Highly Cited
1987
Highly Cited
1987
Inhibition of thromboxane formation in vivo and ex vivo: implications for therapy with platelet inhibitory drugs.
The capacity of platelets to generate thromboxane A2, reflected by measurement of serum thromboxane B2 (TxB2), greatly exceeds… (More)
  • figure 1
  • table 2
  • table 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
1983
Highly Cited
1983
The biological significance of platelet volume: its relationship to bleeding time, platelet thromboxane B2 production and megakaryocyte nuclear DNA concentration.
Bleeding time, platelet thromboxane B2 production and megakaryocyte nuclear DNA concentration were measured in rabbits recovering… (More)
Is this relevant?
Highly Cited
1983
Highly Cited
1983
Endogenous biosynthesis of prostacyclin and thromboxane and platelet function during chronic administration of aspirin in man.
To assess the pharmacologic effects of aspirin on endogenous prostacyclin and thromboxane biosynthesis, 2,3-dinor-6-keto PGF1… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1981
Highly Cited
1981
Release of prostaglandins and thromboxane into the coronary circulation in patients with ischemic heart disease.
Endogenous modulators of platelet aggregability and vascular tone may play a part in coronary-artery disease. We therefore… (More)
Is this relevant?
Highly Cited
1975
Highly Cited
1975
Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides.
An unstable [t1/2 at 37 degrees = 32 +/- 2 (SD) sec] intermediate, thromboxane A2, was detected in the conversion of… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?