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Thromboxane B2
Known as:
Thromboxa-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, (5Z,9alpha,13E,15S)-
, B2, Thromboxane
, Thromboxane B2 [Chemical/Ingredient]
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An eicosanoid and biologically inactive metabolite of thromboxane A2. Thromboxane B2 is released during anaphylaxis. As thromboxane A2 has a short…
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National Institutes of Health
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Related topics
Related topics
20 relations
11-Dehydro thromboxane beta 2:MCnc:Pt:Urine:Qn
11-Dehydro thromboxane beta 2:MRat:24H:Urine:Qn
In Blood
Process of secretion
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Narrower (6)
11-dehydro-2,3-dinor-thromboxane B2
11-dehydro-2,3-dinorthromboxane B3
11-dehydro-thromboxane B2
11-dehydrothromboxane B3
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Broader (1)
Thromboxanes
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
Aspirin-Resistant Thromboxane Biosynthesis and the Risk of Myocardial Infarction, Stroke, or Cardiovascular Death in Patients at High Risk for Cardiovascular Events
J. Eikelboom
,
J. Hirsh
,
J. Weitz
,
M. Johnston
,
Q. Yi
,
S. Yusuf
Circulation
2002
Corpus ID: 2460893
Background—We studied whether aspirin resistance, defined as failure of suppression of thromboxane generation, increases the risk…
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Highly Cited
1998
Highly Cited
1998
Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.
V. Fadok
,
D. Bratton
,
A. Konowal
,
P. W. Freed
,
J. Westcott
,
P. Henson
Journal of Clinical Investigation
1998
Corpus ID: 7707545
Apoptosis in vivo is followed almost inevitably by rapid uptake into adjacent phagocytic cells, a critical process in tissue…
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Highly Cited
1998
Highly Cited
1998
Cyclooxygenase-1 and cyclooxygenase-2 selectivity of widely used nonsteroidal anti-inflammatory drugs.
B. Cryer
,
M. Feldman
American Journal of Medicine
1998
Corpus ID: 35997262
Highly Cited
1996
Highly Cited
1996
Modulation of oxidant stress in vivo in chronic cigarette smokers.
M. Reilly
,
N. Delanty
,
J. Lawson
,
G. FitzGerald
Circulation
1996
Corpus ID: 44606675
BACKGROUND Free radical-induced oxidative damage is thought to be involved in the pathogenesis of diseases associated with…
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Highly Cited
1995
Highly Cited
1995
The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease.
C. Pace-Asciak
,
S. Hahn
,
E. Diamandis
,
G. Soleas
,
D. Goldberg
Clinica chimica acta; international journal of…
1995
Corpus ID: 13170430
Highly Cited
1992
Highly Cited
1992
An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension.
B. Christman
,
C. Mcpherson
,
+4 authors
J. Loyd
New England Journal of Medicine
1992
Corpus ID: 31077387
BACKGROUND Constriction of small pulmonary arteries and arterioles and focal vascular injury are features of pulmonary…
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Highly Cited
1990
Highly Cited
1990
Thromboxane biosynthesis and platelet function in type II diabetes mellitus.
G. Davı̀
,
I. Catalano
,
+4 authors
C. Patrono
New England Journal of Medicine
1990
Corpus ID: 22161533
It has been suggested that platelet hyperreactivity in patients with diabetes mellitus is associated with increased platelet…
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Highly Cited
1983
Highly Cited
1983
Endogenous biosynthesis of prostacyclin and thromboxane and platelet function during chronic administration of aspirin in man.
G. Fitzgerald
,
J. Oates
,
+4 authors
A. Brash
Journal of Clinical Investigation
1983
Corpus ID: 17933008
To assess the pharmacologic effects of aspirin on endogenous prostacyclin and thromboxane biosynthesis, 2,3-dinor-6-keto PGF1…
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Highly Cited
1980
Highly Cited
1980
Low dose aspirin and inhibition of thromboxane B2 production in healthy subjects.
C. Patrono
,
G. Ciabattoni
,
+5 authors
B. Peskar
Thrombosis Research
1980
Corpus ID: 30875966
Highly Cited
1975
Highly Cited
1975
Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides.
M. Hamberg
,
J. Svensson
,
B. Samuelsson
Proceedings of the National Academy of Sciences…
1975
Corpus ID: 22710071
An unstable [t1/2 at 37 degrees = 32 +/- 2 (SD) sec] intermediate, thromboxane A2, was detected in the conversion of…
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