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Thromboxane B2

Known as: Thromboxa-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, (5Z,9alpha,13E,15S)-, B2, Thromboxane, Thromboxane B2 [Chemical/Ingredient] 
An eicosanoid and biologically inactive metabolite of thromboxane A2. Thromboxane B2 is released during anaphylaxis. As thromboxane A2 has a short… 
National Institutes of Health

Related topics

Related topics

20 relations
11-Dehydro thromboxane beta 2:MCnc:Pt:Urine:Qn11-Dehydro thromboxane beta 2:MRat:24H:Urine:QnIn BloodProcess of secretion

Narrower (6)

11-dehydro-2,3-dinor-thromboxane B211-dehydro-2,3-dinorthromboxane B311-dehydro-thromboxane B211-dehydrothromboxane B3

Broader (1)

Thromboxanes

Papers overview

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Highly Cited
2002
Highly Cited
2002
Aspirin-Resistant Thromboxane Biosynthesis and the Risk of Myocardial Infarction, Stroke, or Cardiovascular Death in Patients at High Risk for Cardiovascular Events
Background—We studied whether aspirin resistance, defined as failure of suppression of thromboxane generation, increases the risk… 
Highly Cited
1998
Highly Cited
1998
Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.
Apoptosis in vivo is followed almost inevitably by rapid uptake into adjacent phagocytic cells, a critical process in tissue… 
Highly Cited
1998
Highly Cited
1998
Cyclooxygenase-1 and cyclooxygenase-2 selectivity of widely used nonsteroidal anti-inflammatory drugs.
Highly Cited
1996
Highly Cited
1996
Modulation of oxidant stress in vivo in chronic cigarette smokers.
BACKGROUND Free radical-induced oxidative damage is thought to be involved in the pathogenesis of diseases associated with… 
Highly Cited
1995
Highly Cited
1995
The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease.
Highly Cited
1992
Highly Cited
1992
An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension.
BACKGROUND Constriction of small pulmonary arteries and arterioles and focal vascular injury are features of pulmonary… 
Highly Cited
1990
Highly Cited
1990
Thromboxane biosynthesis and platelet function in type II diabetes mellitus.
It has been suggested that platelet hyperreactivity in patients with diabetes mellitus is associated with increased platelet… 
Highly Cited
1983
Highly Cited
1983
Endogenous biosynthesis of prostacyclin and thromboxane and platelet function during chronic administration of aspirin in man.
To assess the pharmacologic effects of aspirin on endogenous prostacyclin and thromboxane biosynthesis, 2,3-dinor-6-keto PGF1… 
Highly Cited
1980
Highly Cited
1980
Low dose aspirin and inhibition of thromboxane B2 production in healthy subjects.
Highly Cited
1975
Highly Cited
1975
Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides.
An unstable [t1/2 at 37 degrees = 32 +/- 2 (SD) sec] intermediate, thromboxane A2, was detected in the conversion of… 
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