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Thromboxane B2

Known as: Thromboxa-5,13-dien-1-oic acid, 9,11,15-trihydroxy-, (5Z,9alpha,13E,15S)-, B2, Thromboxane, Thromboxane B2 [Chemical/Ingredient] 
An eicosanoid and biologically inactive metabolite of thromboxane A2. Thromboxane B2 is released during anaphylaxis. As thromboxane A2 has a short… 
National Institutes of Health

Related topics

Related topics

20 relations
11-Dehydro thromboxane beta 2:MCnc:Pt:Urine:Qn11-Dehydro thromboxane beta 2:MRat:24H:Urine:QnIn BloodProcess of secretion

Narrower (6)

11-dehydro-2,3-dinor-thromboxane B211-dehydro-2,3-dinorthromboxane B311-dehydro-thromboxane B211-dehydrothromboxane B3

Broader (1)

Thromboxanes

Papers overview

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Highly Cited
1999
Highly Cited
1999
Characterization of rofecoxib as a cyclooxygenase‐2 isoform inhibitor and demonstration of analgesia in the dental pain model
Highly Cited
1994
Highly Cited
1994
Arachidonyl trifluoromethyl ketone, a potent inhibitor of 85-kDa phospholipase A2, blocks production of arachidonate and 12-hydroxyeicosatetraenoic acid by calcium ionophore-challenged platelets.
Highly Cited
1993
Highly Cited
1993
Inhibition by dietary curcumin of azoxymethane-induced ornithine decarboxylase, tyrosine protein kinase, arachidonic acid metabolism and aberrant crypt foci formation in the rat colon.
The present study was designed to investigate the modulatory role of dietary curcumin on (i) azoxymethane (AOM)-induced ornithine… 
Highly Cited
1991
Highly Cited
1991
Erythrocytes metabolically enhance collagen-induced platelet responsiveness via increased thromboxane production, adenosine diphosphate release, and recruitment.
Erythrocytes promoted platelet reactivity in a plasma medium, as demonstrated in an in vitro system that independently evaluated… 
Highly Cited
1990
Highly Cited
1990
Selective inhibition of receptor-coupled phospholipase C-dependent processes in human platelets and polymorphonuclear neutrophils.
Aggregation of human platelets induced by a variety of agonists was inhibited by 1-[6-[[17 beta-3-methoxyestra-1,3,5(10)-trien-17… 
Highly Cited
1986
Highly Cited
1986
11-Dehydrothromboxane B2: a quantitative index of thromboxane A2 formation in the human circulation.
In human plasma, 11-dehydrothromboxane (TX) B2 is a major long lived metabolite (t1/2 45 min) formed from infused TXB2, the… 
Highly Cited
1981
Highly Cited
1981
Release of prostaglandins and thromboxane into the coronary circulation in patients with ischemic heart disease.
Endogenous modulators of platelet aggregability and vascular tone may play a part in coronary-artery disease. We therefore… 
Highly Cited
1981
Highly Cited
1981
Bovine endothelial cells in culture produce thromboxane as well as prostacyclin.
Bovine aortic endothelial and smooth muscle cells in culture were incubated with arachidonic acid or prostaglandin H2. The amount… 
Highly Cited
1980
Highly Cited
1980
Accumulation of Cyclooxygenase Products of Arachidonic Acid Metabolism in Gerbil Brain During Reperfusion After Bilateral Common Carotid Artery Occlusion
: Several of the cyclooxygenase products of arachidonic acid were measured in the cerebral hemispheres of gerbils subjected to… 
Highly Cited
1977
Highly Cited
1977
Imidazole: a selective inhibitor of thromboxane synthetase.
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