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Thromboxane A2

Known as: TXA-2, A2, Thromboxane, 9S,11S-Epoxy,15S-Hydroxy-Thromboxa-5Z,13E-Dien-1-Oic Acid 
An eicosanoid and short-lived intermediate product between prostaglandin endoperoxides and thromboxane B2, with prothrombotic and vasoconstrictive… 
National Institutes of Health

Related topics

Related topics

21 relations

Narrower (9)

10,10-difluorothromboxane A215-hydroperoxythromboxane A2ONO 11113ONO 11120
In BloodProcess of secretionThromboxane alpha 2:MCnc:Pt:Ser:Qnagonists

Broader (2)

Rabbit Aorta Contracting SubstanceThromboxanes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1990
Highly Cited
1990
Human platelets form 3-phosphorylated phosphoinositides in response to alpha-thrombin, U46619, or GTP gamma S.
Highly Cited
1989
Highly Cited
1989
On the mechanism of prostacyclin and thromboxane A2 biosynthesis.
The present research describes studies which address the mechanism of prostacyclin (PGI2) and thromboxane A2 (TXA2) biosynthesis… 
Highly Cited
1986
Highly Cited
1986
Visualization and analysis of mural thrombogenesis on collagen, polyurethane and nylon.
Highly Cited
1983
Highly Cited
1983
Arachidonic acid stimulates the formation of 1,2-diacylglycerol and phosphatidic acid in human platelets. Degree of phospholipase C activation correlates with protein phosphorylation, platelet shape…
Highly Cited
1981
Highly Cited
1981
Vasoconstriction with thromboxane A2 induces ulceration of the gastric mucosa
Thromboxane A2 (TXA2) is formed from the fatty acid precursor, arachidonic acid (AA), by the sequential actions of the enzymes… 
Highly Cited
1981
Highly Cited
1981
Peritoneal fluid thromboxane B2 and 6-keto-prostaglandin F1α in endometriosis☆☆☆
Highly Cited
1980
Highly Cited
1980
Manipulation of platelet aggregation by prostaglandins and their fatty acid precursors: pharmacological basis for a therapeutic approach.
Highly Cited
1979
Highly Cited
1979
Platelet adhesion and aggregation in diabetes mellitus.
Highly Cited
1977
Highly Cited
1977
Application of imidazole as a selective inhibitor thromboxane synthetase in human platelets.
Human platelet suspensions release a rabbit-aorta-contracting substance (previously identified as thromboxane A2) during… 
Highly Cited
1977
Highly Cited
1977
Coronary tone modulation: formation and actions of prostaglandins, endoperoxides, and thromboxanes.
Exogenous prostaglandin (PGE2) contracts bovine and human coronary arteries but its precursor, arachidonic acid, relaxes them… 
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