Thromboxane A2

Known as: TXA-2, A2, Thromboxane, 9S,11S-Epoxy,15S-Hydroxy-Thromboxa-5Z,13E-Dien-1-Oic Acid 
An eicosanoid and short-lived intermediate product between prostaglandin endoperoxides and thromboxane B2, with prothrombotic and vasoconstrictive… (More)
National Institutes of Health

Papers overview

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Review
2008
Review
2008
Thromboxane A(2) (TXA(2)), an unstable arachidonic acid metabolite, elicits diverse physiological/pathophysiological actions… (More)
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Review
2004
Review
2004
Thromboxane A2 receptors (TPs) are widely distributed among different organ systems and have been localized on both cell… (More)
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Highly Cited
2003
Highly Cited
2003
Physical interaction of T cells and dendritic cells (DCs) is essential for T cell proliferation and differentiation, but it has… (More)
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Highly Cited
1999
Highly Cited
1999
Cyclooxygenase-2 (COX-2) inhibitors reduce angiogenic responses to a variety of stimuli, suggesting that products of COX-2 may… (More)
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Highly Cited
1998
Highly Cited
1998
Thromboxane A2 (TXA2) is a labile metabolite of arachidonic acid that has potent biological effects. Its actions are mediated by… (More)
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Highly Cited
1994
Highly Cited
1994
Using subtype-specific antisera, we were able to identify the recently described alpha subunits of G12 and G13 in platelet… (More)
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Highly Cited
1992
Highly Cited
1992
BACKGROUND Constriction of small pulmonary arteries and arterioles and focal vascular injury are features of pulmonary… (More)
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Highly Cited
1991
Highly Cited
1991
BACKGROUND The antithrombotic efficacy of aspirin is attributed to its inhibition of the enzyme prostaglandin G/H synthase, which… (More)
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Review
1991
Review
1991
Thromboxane (Tx) A2 is a product of cyclooxygenase catalyzed metabolism of arachidonic acid. It is formed via prostaglandin (PG… (More)
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Highly Cited
1976
Highly Cited
1976
The microsomal fraction of horse and human platelets contains an enzyme which converts prostaglandin cyclic endoperoxides (PGG2… (More)
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