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Thromboxane A2

Known as: TXA-2, A2, Thromboxane, 9S,11S-Epoxy,15S-Hydroxy-Thromboxa-5Z,13E-Dien-1-Oic Acid 
An eicosanoid and short-lived intermediate product between prostaglandin endoperoxides and thromboxane B2, with prothrombotic and vasoconstrictive… 
National Institutes of Health

Papers overview

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Highly Cited
2002
Highly Cited
2002
Thromboxane (Tx) A2 is a vasoconstrictor and platelet agonist. Aspirin affords cardioprotection through inhibition of TxA2… 
Highly Cited
2002
Highly Cited
2002
Hyperuricemia is associated with renal disease, but it is usually considered a marker of renal dysfunction rather than a risk… 
Highly Cited
1996
Highly Cited
1996
It is our central hypothesis that periodontal diseases, which are chronic Gramnegative infections, represent a previously… 
Highly Cited
1994
Highly Cited
1994
Using subtype-specific antisera, we were able to identify the recently described alpha subunits of G12 and G13 in platelet… 
Highly Cited
1992
Highly Cited
1992
BACKGROUND Constriction of small pulmonary arteries and arterioles and focal vascular injury are features of pulmonary… 
Highly Cited
1979
Highly Cited
1979
ASPIRIN prevents prostaglandin (PG) generation by directly inhibiting the cyclo-oxygenase enzyme responsible for PG biosynthesis1… 
Highly Cited
1979
Highly Cited
1979
PROSTAGLANDINS are potent vasoactive agents with a wide variety of other actions that depend on the species and organ tested and… 
Highly Cited
1976
Highly Cited
1976
Microsomes prepared from rabbit or pig aortas transformed endoperoxides (PGG2 or PGH2) to an unstable substance (PGX) that… 
Highly Cited
1975
Highly Cited
1975
An unstable [t1/2 at 37 degrees = 32 +/- 2 (SD) sec] intermediate, thromboxane A2, was detected in the conversion of…