• Publications
  • Influence
Retinol-binding protein: the transport protein for vitamin A in human plasma.
TLDR
In plasma, RBP apparently circulates as a complex, together with another, larger protein with prealbumin mobility on electrophoresis, which appears to involve both a lipid-protein (retinol-RBP) interaction and a protein- protein (RBP-prealbumin) interaction. Expand
The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes.
TLDR
Immunoprecipitation of [35S]methionine-labeled cyclooxygenase confirmed that the effect of lipopolysaccharide and dexamethasone on the monocyte prostanoid production could be attributed to an increase or decrease, respectively, in cellular cyclo oxygengenase de novo synthesis. Expand
Perioperative Use of β-blockers and COX-2 Inhibitors May Improve Immune Competence and Reduce the Risk of Tumor Metastasis
TLDR
Treatment combining perioperative COX-2 inhibition and β-blockade is practical in operated cancer patients, and this study suggests potential immunological and clinical benefits. Expand
Differential metabolism of dihomo-gamma-linolenic acid and arachidonic acid by cyclo-oxygenase-1 and cyclo-oxygenase-2: implications for cellular synthesis of prostaglandin E1 and prostaglandin E2.
TLDR
It appears that employing a dietary or a combined dietary/pharmacological paradigm to augment the cellular ratio of DGLA/AA is not an effective route to enhance endogenous synthesis of P GE(1) over PGE(2), at least in cells/tissues where COX-1 predominates over COX -2. Expand
Triene prostaglandins: prostacyclin and thromboxane biosynthesis and unique biological properties.
TLDR
It is possible that the triene prostaglandins are potential antithrombotic agents because their precursor fatty acids, as well as their transformation products, PGH, thromboxane A(3), and PGI, are capable of interfering with aggregation of platelets in platelet-rich plasma. Expand
Thromboxanes: selective biosynthesis and distinct biological properties.
TLDR
The observations indicate the remarkable structural specificity of both the synthetic enzymes, cyclooxygenase and thromboxane synthetase, as well as the vascular and platelet receptor sites. Expand
The interaction of thyroxine with human plasma prealbumin and with the prealbumin-retinol-binding protein complex.
  • A. Raz, D. Goodman
  • Medicine, Chemistry
  • The Journal of biological chemistry
  • 25 June 1969
TLDR
The interaction of pre Albumin with thyroxine appears to be independent of the prealbumin-retinol-binding protein interaction, and the binding capacity and affinity of pre albumin for thyroxin were similar in the presence and absence of retinol -binding protein. Expand
Identification of a cyclooxygenase-related gene and its potential role in prostaglandin formation.
TLDR
Rehybridization of Northern blots at lower stringency revealed the presence of a new tissue-specific 4.0 kb mRNA species exhibiting increased expression during cell culture, and its relatedness to cyclooxygenase and its increase in parallel with enzymatic activity suggest that the larger mRNA may encode for a cyclo oxygengenase. Expand
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