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Eicosanoids

Known as: icosanoid, Icosanoids, Eicosanoid 
A class of compounds named after and generally derived from C20 fatty acids (EICOSANOIC ACIDS) that includes PROSTAGLANDINS; LEUKOTRIENES… 
National Institutes of Health

Related topics

Related topics

19 relations

Narrower (8)

ARACHIDYL GLUCOSIDEArachidonic AcidLeukotrienesProstaglandins
Eicosanoid ReceptorIn BloodProcess of secretionagonists

Broader (1)

Fatty Acids, Unsaturated

Papers overview

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Highly Cited
1991
Highly Cited
1991
Evidence that hydrolysis of ethanolamine plasmalogens triggers synthesis of platelet-activating factor via a transacylation reaction.
Review
1990
Review
1990
Substrate specificities and functions of the P450 cytochromes.
Highly Cited
1990
Highly Cited
1990
Polydipsia in rhesus monkeys deficient in omega-3 fatty acids
Highly Cited
1989
Highly Cited
1989
Plasmenylethanolamine is the major storage depot for arachidonic acid in rabbit vascular smooth muscle and is rapidly hydrolyzed after angiotensin II stimulation.
The present study demonstrates that rabbit aortic intimal smooth muscle cells contain the majority of their endogenous… 
Highly Cited
1989
Highly Cited
1989
Eicosanoids and multistage carcinogenesis in NMRI mouse skin: role of prostaglandins E and F in conversion (first stage of tumor promotion) and promotion (second stage of tumor promotion).
When applied to NMRI mouse skin in vivo, phorbol esters such as 12-O-tetradecanoylphorbol-13-acetate (TPA) and 12-O… 
Highly Cited
1986
Highly Cited
1986
Increased thromboxane biosynthesis in a human preparation of platelet activation: biochemical and functional consequences of selective inhibition of thromboxane synthase.
Although thromboxane A2 is a potent platelet agonist and vasoconstrictor in vitro, our knowledge of its pathophysiologic… 
Highly Cited
1984
Highly Cited
1984
Analysis of leukotrienes, prostaglandins, and other oxygenated metabolites of arachidonic acid by high-performance liquid chromatography.
Highly Cited
1983
Highly Cited
1983
The effects of BW755C and other anti‐inflammatory drugs on eicosanoid concentrations and leukocyte accumulation in experimentally‐induced acute inflammation
BW755C (3‐amino‐1‐[m‐trifluoromethyl)phenyl]‐2‐pyrazoline HCl) reduced the concentration of leukotriene B4 (LTB4), thromboxane B2… 
Highly Cited
1982
Highly Cited
1982
Albumin stabilizes leukotriene A4.
Highly Cited
1981
Highly Cited
1981
Radioimmunoassay of the leukotrienes of slow reacting substance of anaphylaxis.
A rabbit immunized with a conjugate of leukotriene D4 (LTD4) and bovine albumin via the icosanoid carboxyl produced antibodies… 
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