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Leukotrienes
Known as:
Leukotriene
, Leukotrienes [Chemical/Ingredient]
A family of biologically active compounds derived from arachidonic acid by oxidative metabolism through the 5-lipoxygenase pathway. They participate…
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National Institutes of Health
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Related topics
Related topics
25 relations
Narrower (13)
12-HPETE
14,15-dihydroperoxyeicosatetraenoic acid
5,15-dihydroperoxyeicosatetraenoic acid
8,15-diHPETE
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Broader (2)
Arachidonic Acid
Eicosanoids
Immediate hypersensitivity
In Blood
Inflammation
Leukotriene Receptor
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Mechanisms of disease: Leukotrienes
M. Peters-Golden
,
W. Henderson
2007
Corpus ID: 80255960
From the Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Health System…
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Review
2001
Review
2001
Prostaglandins and leukotrienes: advances in eicosanoid biology.
C. Funk
Science
2001
Corpus ID: 12564549
Prostaglandins and leukotrienes are potent eicosanoid lipid mediators derived from phospholipase-released arachidonic acid that…
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Review
1999
Review
1999
Peroxisome proliferator-activated receptors: nuclear control of metabolism.
B. Desvergne
,
W. Wahli
Endocrine reviews
1999
Corpus ID: 2586436
I. Introduction II. Molecular Aspects A. PPAR isotypes: identity, genomic organization and chromosomal localization B. DNA…
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Highly Cited
1999
Highly Cited
1999
Characterization of the human cysteinyl leukotriene CysLT1 receptor
K. Lynch
,
G. O'neill
,
+20 authors
Jilly F. Evans
Nature
1999
Corpus ID: 4423645
The cysteinyl leukotrienes—leukotriene C4(LTC4), leukotriene D4(LTD4) and leukotriene E4(LTE 4)—are important mediators of human…
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Highly Cited
1996
Highly Cited
1996
The PPARα–leukotriene B4 pathway to inflammation control
P. Devchand
,
H. Keller
,
J. Peters
,
M. Vázquez
,
F. Gonzalez
,
W. Wahli
Nature
1996
Corpus ID: 4347185
Inflammation is a local immune response to 'foreign' molecules, infection and injury. Leukotriene B4, a potent chemotactic agent…
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Review
1994
Review
1994
The Role of Leukotrienes in Inflammation
W. Henderson
Annals of Internal Medicine
1994
Corpus ID: 34810055
Leukotrienes, together with prostaglandins, thromboxanes, and lipoxins, are the major constituents of a group of biologically…
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Review
1990
Review
1990
Leukotrienes and other products of the 5-lipoxygenase pathway. Biochemistry and relation to pathobiology in human diseases.
R. Lewis
,
K. Austen
,
R. Soberman
The New England journal of medicine
1990
Corpus ID: 5815084
THE slow-reacting substance of anaphylaxis was recognized as a discrete biologic entity 1 , 2 three to four decades before it was…
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Highly Cited
1990
Highly Cited
1990
Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis
R. Dixon
,
R. Diehl
,
+5 authors
D. K. Miller
Nature
1990
Corpus ID: 4326434
LEUKOTRIENES, the biologically active metabolites of arachidonic acid, have been implicated in a variety of inflammatory…
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Review
1987
Review
1987
Leukotrienes and lipoxins: structures, biosynthesis, and biological effects.
B. Samuelsson
,
S. Dahlén
,
J. Lindgren
,
C. Rouzer
,
C. Serhan
Science
1987
Corpus ID: 43753152
Arachidonic acid is released from membrane phospholipids upon cell stimulation (for example, by immune complexes and calcium…
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Highly Cited
1980
Highly Cited
1980
Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes
A. Ford-hutchinson
,
M. A. Bray
,
M. Doig
,
M. E. Shipley
,
M. J. Smith
Nature
1980
Corpus ID: 10581791
Arachidonic acid is metabolised either by cyclooxygenases to produce prostaglandins and thromboxanes or by lipoxygenases to…
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