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Leukotrienes

Known as: Leukotriene, Leukotrienes [Chemical/Ingredient] 
A family of biologically active compounds derived from arachidonic acid by oxidative metabolism through the 5-lipoxygenase pathway. They participate… 
National Institutes of Health

Related topics

Related topics

25 relations

Narrower (13)

12-HPETE14,15-dihydroperoxyeicosatetraenoic acid5,15-dihydroperoxyeicosatetraenoic acid8,15-diHPETE

Broader (2)

Arachidonic AcidEicosanoids
Immediate hypersensitivityIn BloodInflammationLeukotriene Receptor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Relationship of exhaled nitric oxide to clinical and inflammatory markers of persistent asthma in children.
Review
2001
Review
2001
Leukotriene B4: metabolism and signal transduction.
Leukotriene B4 (LTB4) is known as one of the most potent chemoattractants and activators of leukocytes and is involved in… 
Highly Cited
1999
Highly Cited
1999
Biosynthesis and regulation of microbial polyunsaturated fatty acid production.
Highly Cited
1995
Highly Cited
1995
Cytokine secretion and eicosanoid production in the peripheral blood mononuclear cells of MS patients undergoing dietary supplementation with n-3 polyunsaturated fatty acids
Highly Cited
1993
Highly Cited
1993
Epidermal growth factor—induced actin remodeling is regulated by 5-lipoxygenase and cyclooxygenase products
Highly Cited
1985
Highly Cited
1985
Leukotrienes augment interleukin 1 production by human monocytes.
The effects of leukotrienes (LT) on production of interleukin 1 (IL 1) by human peripheral blood monocytes were examined. LTB4… 
Highly Cited
1985
Highly Cited
1985
Metabolism of arachidonic acid in acetic acid colitis in rats. Similarity to human inflammatory bowel disease.
Highly Cited
1983
Highly Cited
1983
Inhibition by prostaglandins of leukotriene B4 release from activated neutrophils.
Chemoattractant N-formylmethionylleucylphenylalanine (fMet-Leu-Phe) in the presence of cytochalasin B stimulates the release of… 
Highly Cited
1982
Highly Cited
1982
Nonimmunological production of leukotrienes induced by platelet-activating factor.
Platelet-activating factor caused rapid pulmonary vasoconstriction and edema in isolated lungs perfused with albumin-free salt… 
Review
1981
Review
1981
Mediation of local homeostasis and inflammation by leukotrienes and other mast cell-dependent compounds
The oxidative products of arachidonic acid and other mediators of immediate hypersensitivity are released by mast cells and other… 
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