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Leukotrienes

Known as: Leukotriene, Leukotrienes [Chemical/Ingredient] 
A family of biologically active compounds derived from arachidonic acid by oxidative metabolism through the 5-lipoxygenase pathway. They participate… 
National Institutes of Health

Related topics

Related topics

25 relations

Narrower (13)

12-HPETE14,15-dihydroperoxyeicosatetraenoic acid5,15-dihydroperoxyeicosatetraenoic acid8,15-diHPETE

Broader (2)

Arachidonic AcidEicosanoids
Immediate hypersensitivityIn BloodInflammationLeukotriene Receptor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
A concept for G protein activation by G protein-coupled receptor dimers: the transducin/rhodopsin interface
G protein-coupled receptors (GPCRs) are ubiquitous and essential in modulating virtually all physiological processes. These… 
Highly Cited
1995
Highly Cited
1995
Induction of heat-shock protein 72 protects against ischemia/reperfusion in rat small intestine.
Highly Cited
1993
Highly Cited
1993
Mediators of leukocyte adhesion in rat mesenteric venules elicited by inhibition of nitric oxide synthesis.
Review
1992
Review
1992
Designing therapeutically effective 5-lipoxygenase inhibitors.
Highly Cited
1986
Highly Cited
1986
Arachidonate 12-lipoxygenase purified from porcine leukocytes by immunoaffinity chromatography and its reactivity with hydroperoxyeicosatetraenoic acids.
Highly Cited
1985
Highly Cited
1985
Allergen‐Induced Release of Sulphidopeptide Leukotrienes (SRS‐A) and LTB4 in Allergic Rhinitis
Leukotrienes are a recently discovered group of arachidonic acid‐derived lipid mediators. Using radioimmunoassay and high… 
Highly Cited
1983
Highly Cited
1983
Direct demonstration of increased intracellular concentration of free calcium in rabbit and human neutrophils following stimulation by chemotactic factor.
Highly Cited
1983
Highly Cited
1983
Stereospecific inhibition of PGH2-induced platelet aggregation by lipoxygenase products of icosaenoic acids.
Highly Cited
1981
Highly Cited
1981
Transformation of arachidonic acid in leukocytes. Isolation and structural analysis of a novel dihydroxy derivative.
Highly Cited
1981
Highly Cited
1981
Effect of various lipoxygenase metabolites of arachidonic acid on degranulation of polymorphonuclear leukocytes.
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