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Leukotrienes

Known as: Leukotriene, Leukotrienes [Chemical/Ingredient] 
A family of biologically active compounds derived from arachidonic acid by oxidative metabolism through the 5-lipoxygenase pathway. They participate… Expand
National Institutes of Health

Related topics

Related topics

25 relations

Narrower (13)

12-HPETE14,15-dihydroperoxyeicosatetraenoic acid5,15-dihydroperoxyeicosatetraenoic acid8,15-diHPETE
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Broader (2)

Arachidonic AcidEicosanoids
Immediate hypersensitivityIn BloodInflammationLeukotriene Receptor
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Chronic diseases, inflammation, and spices: how are they linked?
Extensive research within the last several decades has revealed that the major risk factors for most chronic diseases are… Expand
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Review
2017
Review
2017
Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines—2016 revision
Background: Allergic rhinitis (AR) affects 10% to 40% of the population. It reduces quality of life and school and work… Expand
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Review
2017
Review
2017
STOPPFrail (Screening Tool of Older Persons Prescriptions in Frail adults with limited life expectancy): consensus validation
Objective to validate STOPPFrail, a list of explicit criteria for potentially inappropriate medication (PIM) use in frail older… Expand
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Review
2016
Review
2016
Targeting arachidonic acid pathway by natural products for cancer prevention and therapy.
Arachidonic acid (AA) pathway, a metabolic process, plays a key role in carcinogenesis. Hence, AA pathway metabolic enzymes… Expand
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Review
2016
Review
2016
Neutrophils: Their Role in Innate and Adaptive Immunity
Polymorphonuclear neutrophils (PMNs) are the most abundant leukocytes in the blood and constitute the first line of host defense… Expand
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Review
2006
Review
2006
n-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases.
  • Philip C Calder
  • The American journal of clinical nutrition
  • 2006
    • Corpus ID: 13659230
Inflammation is part of the normal host response to infection and injury. However, excessive or inappropriate inflammation… Expand
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Review
2001
Review
2001
Prostaglandins and leukotrienes: advances in eicosanoid biology.
Prostaglandins and leukotrienes are potent eicosanoid lipid mediators derived from phospholipase-released arachidonic acid that… Expand
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Review
1999
Review
1999
Peroxisome proliferator-activated receptors: nuclear control of metabolism.
I. Introduction II. Molecular Aspects A. PPAR isotypes: identity, genomic organization and chromosomal localization B. DNA… Expand
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Highly Cited
1998
Highly Cited
1998
Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.
Apoptosis in vivo is followed almost inevitably by rapid uptake into adjacent phagocytic cells, a critical process in tissue… Expand
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Review
1987
Review
1987
Leukotrienes and lipoxins: structures, biosynthesis, and biological effects.
Arachidonic acid is released from membrane phospholipids upon cell stimulation (for example, by immune complexes and calcium… Expand
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