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Leukotrienes

Known as: Leukotriene, Leukotrienes [Chemical/Ingredient] 
A family of biologically active compounds derived from arachidonic acid by oxidative metabolism through the 5-lipoxygenase pathway. They participate… Expand
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
From the Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Health System… Expand
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Review
2001
Review
2001
  • C. Funk
  • Science
  • 2001
  • Corpus ID: 12564549
Prostaglandins and leukotrienes are potent eicosanoid lipid mediators derived from phospholipase-released arachidonic acid that… Expand
Review
1999
Review
1999
I. Introduction II. Molecular Aspects A. PPAR isotypes: identity, genomic organization and chromosomal localization B. DNA… Expand
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Highly Cited
1999
Highly Cited
1999
The cysteinyl leukotrienes—leukotriene C4(LTC4), leukotriene D4(LTD4) and leukotriene E4(LTE 4)—are important mediators of human… Expand
Highly Cited
1996
Highly Cited
1996
Inflammation is a local immune response to 'foreign' molecules, infection and injury. Leukotriene B4, a potent chemotactic agent… Expand
Review
1990
Review
1990
THE slow-reacting substance of anaphylaxis was recognized as a discrete biologic entity 1 , 2 three to four decades before it was… Expand
Review
1987
Review
1987
Arachidonic acid is released from membrane phospholipids upon cell stimulation (for example, by immune complexes and calcium… Expand
Highly Cited
1981
Highly Cited
1981
Leukotrienes B4, C4, and D4, members of a recently discovered family of substances biosynthesized from arachidonic acid, were… Expand
Highly Cited
1980
Highly Cited
1980
Arachidonic acid is metabolised either by cyclooxygenases to produce prostaglandins and thromboxanes or by lipoxygenases to… Expand
Highly Cited
1979
Highly Cited
1979
Murine mastocytoma cells treated with calcium ionophore A23187 produced a slow-reacting substance (SRS) that caused guinea pig… Expand
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