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12-HPETE

Known as: (S-(E,E,E))-12-hydroperoxy-5,8,10,14-eicosatetraenoic acid, 12-hydroperoxy-5,8,10,14-icosatetraenoic acid 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

LeukotrienesPlatelet Aggregation InhibitorsVasoconstrictor Agents

Narrower (1)

arachidonic acid omega-9 hydroperoxide

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1997
1997
12-HETE and 12-HPETE potently stimulate intracellular release of calcium in intact human neutrophils.
1994
1994
Hepoxilin A3 formation in the rat pineal gland selectively utilizes (12S)-hydroperoxyeicosatetraenoic acid (HPETE), but not (12R)-HPETE.
Highly Cited
1989
Highly Cited
1989
Products of heme-catalyzed transformation of the arachidonate derivative 12-HPETE open S-type K+ channels in Aplysia
1986
1986
Potentiation of 5-lipoxygenase metabolism by human neutrophils using a combination of activators.
Highly Cited
1986
Highly Cited
1986
Clinical and epidemiological studies of eicosapentaenoic acid (EPA) in Japan.
1985
1985
Inhibition of thromboxane and 12-HPETE formation by dazoxiben and its two thiophenic acid-substituted derivatives.
1985
1985
Lipoxygenase products: leukotrienes C4, D4, A4's breakdown products and 12-HPETE influence platelet aggregation in vivo.
Review
1985
Review
1985
A review of possible roles of the platelet 12-lipoxygenase.
THE 12-LIPOXYGENASE ENZYME of platelets was the first lipoxygenase to be discovered in animal tissue,1 yet its physiologic… 
1984
1984
The Effects of Molsidomine and Its Metabolite SIN‐1 on Coronary Vessel Tone, Platelet Aggregation, and Eicosanoid Formation In Vitro—Inhibition of 12‐HPETE Biosynthesis
We studied the action of the biologically active metabolite of molsidomine, N-morpholino-N-nitrosoamino-acetonitrile (SIN), on… 
1981
1981
Investigation of the vascular actions of arachidonate lipoxygenase and cyclo-oxygenase products on the isolated perfused stomach of rat and rabbit.
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