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Detection of superoxide anion released extracellularly by endothelial cells using cytochrome c reduction, ESR, fluorescence and lucigenin-enhanced chemiluminescence techniques.
Endothelium produces oxygen-derived free radicals (nitric oxide, NO&z.rad;; superoxide anion, O(2)(*-)) which play a major role in physiology and pathology of the vessel wall. However, little isExpand
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Nature of the cardiomyocyte injury induced by lipid hydroperoxides.
OBJECTIVE As a result of oxidative stress to membrane lipid matrix, the peroxidation of polyunsaturated fatty acids induced the transient formation of lipid hydroperoxides (ROOH). The aim of thisExpand
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Purines and cell death
Increasing evidence suggests that adenosine and ATP not only modulate cell growth and differentiation, but may also act as inducers of cell death. In the session “Purines and cell death,” held duringExpand
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Monohydroperoxidized fatty acids but not 4-hydroxynonenal induced acute cardiac cell damage.
Unsaturated fatty acids constitutive of cardiac membranal lipid matrix are one of the primary targets for reactive oxygen species generated during ischemia-reperfusion cycle. Lipid peroxidation is aExpand
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Evolution of the sensitivity of isolated adipocytes of ewes to the antilipolytic action of adenosine during pregnancy and lactation.
Four successive biopsies of omental adipose tissue were performed on the 43rd, 100th, 140th days of pregnancy and during the 3rd week of lactation in 6 "Pré-Alpes" ewes. Using incubated isolatedExpand
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In vitro photodynamic lipid peroxidation of total lipophilic extracts from leaves of bean plants.
In vitro lipid peroxidation, induced by reactive oxygen species photochemically generated, was carried out on purified alpha-linolenic acid (18:3(n - 3)) and on bean leaf total lipophilic extracts.Expand
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In Vitro and Ex Vivo Inhibition of the Modification of Low‐Density Lipoprotein by Indapamide
Summary: The effect of an antihypertensive drug, indapamide, on copper- and endothelial cell-induced peroxidation of human low-density lipoprotein (LDL) was studied and compared with that of drugsExpand
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Evolution of the sensitivity of isolated adipocytes of ewes to the lipolytic effects of different stimuli during pregnancy and lactation.
Four successive biopsies of omental adipose tissue were performed at 43,100,140 days and during the 3rd week of lactation on 6 "Pré-Alpes" ewes. Using isolated adipocyte incubation, we studied theExpand
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■ Mathematical treatment of chemiluminescence data allowing an optimised kinetic analysis of vascular NAD(P)H-dependent superoxide anion production
Regulation of vascular redox homeostasis plays a central role in the control of vascular tone (e.g.: redox modulation of endothelial NO synthase and soluble guanylate cyclase activities). SuperoxideExpand
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Potentiation of 5-lipoxygenase metabolism by human neutrophils using a combination of activators.
Platelet-derived 12-hydroperoxy-5,8,10,14-icosatetraenoic acid (12-HPETE) cannot increase the synthesis of leukotriene B4 metabolites by human neutrophils activated byExpand
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