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Arachidonic Acid
Known as:
5,8,11,14-Eicosatetraenoic acid, (all-Z)-
, Fatty Acid 20:4 n-6
, acid arachidonic
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An unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent…
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National Institutes of Health
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Related topics
Related topics
14 relations
Narrower (3)
Arachidonic Acid, Sodium Salt
FOG7 chemotactic
Leukotrienes
Broader (2)
Eicosanoids
arachidonate
Eicosatetraenoic Acids
In Blood
Process of secretion
agonists
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Docosahexaenoic and arachidonic acid concentrations in human breast milk worldwide.
J. Brenna
,
Behzad Varamini
,
R. G. Jensen
,
D. Diersen-Schade
,
Julia A Boettcher
,
L. Arterburn
American Journal of Clinical Nutrition
2007
Corpus ID: 4509871
Concentrations of the long-chain polyunsaturated fatty acids (LCPUFAs) docosahexaenoic acid (DHA, 22:6n-3) and arachidonic acid…
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Highly Cited
2003
Highly Cited
2003
Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels
Hiroyuki Watanabe
,
J. Vriens
,
J. Prenen
,
G. Droogmans
,
T. Voets
,
B. Nilius
Nature
2003
Corpus ID: 4349286
TRPV4 is a widely expressed cation channel of the ‘transient receptor potential’ (TRP) family that is related to the vanilloid…
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Review
2002
Review
2002
P-450 metabolites of arachidonic acid in the control of cardiovascular function.
R. Roman
Physiological Reviews
2002
Corpus ID: 8980415
Recent studies have indicated that arachidonic acid is primarily metabolized by cytochrome P-450 (CYP) enzymes in the brain, lung…
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Review
2001
Review
2001
Arachidonic acid as a bioactive molecule.
A. Brash
Journal of Clinical Investigation
2001
Corpus ID: 207745824
Arachidonic acid is a slippery molecule that owes its mobility to its four cis double bonds. These are the source of its…
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Highly Cited
1996
Highly Cited
1996
Suppression of Intestinal Polyposis in Apc Δ716 Knockout Mice by Inhibition of Cyclooxygenase 2 (COX-2)
M. Oshima
,
J. Dinchuk
,
+6 authors
M. Taketo
Cell
1996
Corpus ID: 16412817
Highly Cited
1995
Highly Cited
1995
Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
M. Tsujii
,
R. Dubois
Cell
1995
Corpus ID: 11037319
Highly Cited
1994
Highly Cited
1994
Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas.
C. Eberhart
,
R. Coffey
,
A. Radhika
,
F. Giardiello
,
S. Ferrenbach
,
R. Dubois
Gastroenterology
1994
Corpus ID: 23895827
Highly Cited
1992
Highly Cited
1992
Isolation and structure of a brain constituent that binds to the cannabinoid receptor.
W. Devane
,
L. Hanuš
,
+7 authors
R. Mechoulam
Science
1992
Corpus ID: 23490246
Arachidonylethanolamide, an arachidonic acid derivative in porcine brain, was identified in a screen for endogenous ligands for…
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Review
1980
Review
1980
Prostaglandins, arachidonic acid, and inflammation.
F. Kuehl
,
Egan Rw
Science
1980
Corpus ID: 33378381
The enzymatic oxidation of arachidonic acid has been shown to yield potent pathological agents by two major pathways. Those of…
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Highly Cited
1974
Highly Cited
1974
Prostaglandin endoperoxides. Novel transformations of arachidonic acid in human platelets.
M. Hamberg
,
B. Samuelsson
Proceedings of the National Academy of Sciences…
1974
Corpus ID: 26547547
Arachidonic acid incubated with human platelets was converted into three compounds, 12L-hydroxy-5,8,10,14-eicosatetraenoic acid…
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