Arachidonic Acid

Known as: 5,8,11,14-Eicosatetraenoic acid, (all-Z)-, Fatty Acid 20:4 n-6, acid arachidonic 
An unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent… (More)
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Concentrations of the long-chain polyunsaturated fatty acids (LCPUFAs) docosahexaenoic acid (DHA, 22:6n-3) and arachidonic acid… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Leukotrienes are inflammatory mediators generated from arachidonic acid (polyunsaturated n-6 fatty acid) by the enzyme… (More)
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Highly Cited
2003
Highly Cited
2003
TRPV4 is a widely expressed cation channel of the ‘transient receptor potential’ (TRP) family that is related to the vanilloid… (More)
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Review
2002
Review
2002
Recent studies have indicated that arachidonic acid is primarily metabolized by cytochrome P-450 (CYP) enzymes in the brain, lung… (More)
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Review
2000
Review
2000
Many antiinflammatory pharmaceutical products inhibit the production of certain eicosanoids and cytokines and it is here that… (More)
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Highly Cited
2000
Highly Cited
2000
Cyclooxygenase-2 (COX-2) is up-regulated in many cancers and is a rate-limiting step in colon carcinogenesis. Nonsteroidal… (More)
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Highly Cited
1996
Highly Cited
1996
Endothelial cells release several compounds, including prostacyclin, NO, and endothelium-derived hyperpolarizing factor (EDHF… (More)
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Highly Cited
1995
Highly Cited
1995
Cyclooxygenases 1 and 2 (COX-1 and COX-2) are key enzymes in prostaglandin biosynthesis and the target enzymes for the widely… (More)
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Highly Cited
1991
Highly Cited
1991
We report the cloning and expression of a cDNA encoding a high molecular weight (85.2 kd) cytosolic phospholipase A2 (cPLA2) that… (More)
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Review
1987
Review
1987
Arachidonic acid metabolites can act as tumor promoters and can affect growth and metastases of tumors in three ways: (a… (More)
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