arachidonate

BACKGROUND Leukotrienes are inflammatory mediators generated from arachidonic acid (polyunsaturated n-6 fatty acid) by the enzyme… (More)

BACKGROUND RAGE (receptor for advanced glycation end products [AGEs]) plays a role in diabetic atherosclerosis. Recently, we have… (More)

Endophilin I is a presynaptic protein of unknown function that binds to dynamin, a GTPase that is implicated in endocytosis and… (More)

Diets high in fat are associated with an increased risk of prostate cancer, although the molecular mechanism is still unknown. We… (More)

Regulation of adipose cell mass is a critical homeostatic process in higher vertebrates. The conversion of fibroblasts into cells… (More)

Anandamide (N-arachidonoyl-ethanolamine) was recently identified as a brain arachidonate derivative that binds to and activates… (More)

Treatment of cells with agents that stimulate the release of arachidonic acid causes increased serine phosphorylation and… (More)

The function of the nephron, the anatomical unit of the kidney, is segmented; at least 12 segments have been identified that… (More)

We provide evidence that the mechanism for arachidonate release from stimulated human platelets involves two enzymes: a… (More)