arachidonate

The cycle of deacylation and reacylation of phospholipids plays a critical role in regulating availability of arachidonic acid… Expand

BACKGROUND RAGE (receptor for advanced glycation end products [AGEs]) plays a role in diabetic atherosclerosis. Recently, we have… Expand

Cyclooxygenases metabolize arachidonate to five primary prostanoids: PGE(2), PGF(2 alpha), PGI(2), TxA(2), and PGD(2). These… Expand

Brain ischemia and reperfusion engage multiple independently-fatal terminal pathways involving loss of membrane integrity in… Expand

The cyclooxygenase (COX) enzymes catalyze a key step in the conversion of arachidonate to PGH2, the immediate substrate for a… Expand

Regulation of adipose cell mass is a critical homeostatic process in higher vertebrates. The conversion of fibroblasts into cells… Expand

ANANDAMIDE (N-arachidonoyl-ethanolamine) was recently identified as a brain arachidonate derivative that binds to and activates… Expand

Treatment of cells with agents that stimulate the release of arachidonic acid causes increased serine phosphorylation and… Expand

Publisher Summary This chapter discusses the mechanisms and roles of apoptosis in pathology. Necrosis differs from apoptosis in… Expand

The thiobarbituric acid reacting material produced during enzymatic microsomal lipid peroxidation has been identified as… Expand