Arachidonic Acid, Sodium Salt

Known as: Arachidonate, Sodium, Sodium Arachidonate 
 
National Institutes of Health

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Arachidonic Acid

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2005
2005
Assessment of the antiplatelet effects of low to medium dose aspirin in the early and late phases after ischaemic stroke and TIA.
Vascular events commonly recur in stroke patients on aspirin, and may reflect incomplete inhibition of platelet function with… (More)
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Highly Cited
2001
Highly Cited
2001
Thalidomide and its analogues inhibit lipopolysaccharide-mediated Iinduction of cyclooxygenase-2.
We investigated the effect of thalidomide, a compound with immunomodulatory and antiangiogenic properties, on lipopolysaccharide… (More)
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Highly Cited
1990
Highly Cited
1990
Enhanced platelet adherence and aggregation in Chagas' disease: a potential pathogenic mechanism for cardiomyopathy.
Spasm and thrombosis of the coronary microcirculation has been implicated in the pathogenesis of the cardiomyopathy of Chagas… (More)
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Highly Cited
1984
Highly Cited
1984
Oxygen radicals mediate the cerebral arteriolar dilation from arachidonate and bradykinin in cats.
Topical application of sodium arachidonate (50-200 micrograms/ml) or bradykinin (0.1-10 micrograms/ml) on the brain surface of… (More)
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1984
1984
Platelet impedance aggregation in whole blood and its inhibition by antiplatelet drugs.
Platelet aggregation was studied in citrated whole blood by an electrical impedance method. Blood samples from normal volunteers… (More)
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1983
1983
Inhibition of human platelet aggregation by S-nitrosothiols. Heme-dependent activation of soluble guanylate cyclase and stimulation of cyclic GMP accumulation.
Recent studies have suggested that cyclic GMP accumulation in platelets mediates the antiaggregatory effects of certain nitrogen… (More)
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Highly Cited
1979
Highly Cited
1979
Recovery of endothelial cell prostacyclin production after inhibition by low doses of aspirin.
Endothelial cells synthesize prostacyclin (PGI(2)), an unstable prostaglandin that inhibits platelet aggregation and serotonin… (More)
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Highly Cited
1978
Highly Cited
1978
Stimulation of endothelial cell prostacyclin production by thrombin, trypsin, and the ionophore A 23187.
Prostacyclin (PGI(2)) is an unstable prostaglandin which inhibits platelet aggregation and serotonin release and causes… (More)
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Highly Cited
1978
Highly Cited
1978
Brain edema: induction in cortical slices by polyunsaturated fatty acids.
The presence of polyunsaturated and saturated fatty acids in leukocytic membranes prompted study of their possible role in the… (More)
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Highly Cited
1977
Highly Cited
1977
Prostacyclin (PGX) is the endogenous metabolite responsible for relaxation of coronary arteries induced by arachindonic acid.
The actions of prostacyclin (PGX) and several other derivatives of arachidonic acid were examined on spiral-strips of bovine… (More)
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