T-helper cell type 1

Known as: Th1 Cell, Type 1 T-helper cell, Cell, Th1 
Type 1 Helper Cells are a subset of helper-inducer T-lymphocytes which synthesize and secrete interleukin-2, gamma-interferon, and interleukin-12… (More)
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Interleukin 17 (IL-17)–producing T helper cells (TH-17 cells) have been characterized in mice as a distinct subset of effector… (More)
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Highly Cited
2007
Highly Cited
2007
The cytokine transforming growth factor-beta (TGF-beta) converts naïve T cells into regulatory T (Treg) cells that prevent… (More)
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Highly Cited
2007
Highly Cited
2007
Recent work has identified a new subset of effector T cells that produces interleukin (IL)-17 known as T helper 17 (Th17) cells… (More)
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Highly Cited
2003
Highly Cited
2003
A long-standing paradox in cellular immunology concerns the conditional requirement for CD4+ T-helper (TH) cells in the priming… (More)
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Highly Cited
2002
Highly Cited
2002
T-bet is a member of the T-box family of transcription factors that appears to regulate lineage commitment in CD4 T helper (TH… (More)
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Review
2002
Review
2002
After encountering antigen, helper T (T(H)) cells undergo differentiation to effector cells, which can secrete high levels of… (More)
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Highly Cited
1997
Highly Cited
1997
The developmental commitment to a T helper 1 (Th1)- or Th2-type response can significantly influence host immunity to pathogens… (More)
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Highly Cited
1995
Highly Cited
1995
BACKGROUND Cytomegalovirus (CMV) disease in immunocompromised patients correlates with a deficiency of CD8+ cytotoxic T… (More)
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Highly Cited
1992
Highly Cited
1992
BACKGROUND In atopic asthma, activated T helper lymphocytes are present in bronchial-biopsy specimens and bronchoalveolar-lavage… (More)
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Highly Cited
1986
Highly Cited
1986
A panel of antigen-specific mouse helper T cell clones was characterized according to patterns of lymphokine activity production… (More)
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