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T-helper cell type 1
Known as:
Th1 Cell
, Type 1 T-helper cell
, Cell, Th1
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Type 1 Helper Cells are a subset of helper-inducer T-lymphocytes which synthesize and secrete interleukin-2, gamma-interferon, and interleukin-12…
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National Institutes of Health
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Related topics
Related topics
13 relations
Broader (3)
CD4 Positive T Lymphocytes
Helper-Inducer T-Lymphocyte
T-Lymphocyte
CD8-Positive T-Lymphocytes
Hematopoietic and Lymphoid Tissue
Hepatitis A Virus Cellular Receptor 2
IL27RA protein, human
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Histamine H4 receptors modulate dendritic cell migration through skin – immunomodulatory role of histamine
W. Bäumer
,
S. Wendorff
,
+5 authors
Manfred Kietzmann
Allergy. European Journal of Allergy and Clinical…
2008
Corpus ID: 1836887
Background: Dendritic cells (DC) are the major antigen‐presenting cells and play a key role in adaptive immunity as they are…
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Highly Cited
1999
Highly Cited
1999
CD 8 a 1 and CD 8 a 2 Subclasses of Dendritic Cells Direct the Development of Distinct T Helper Cells In Vivo
By Roberto Maldonado-López
,
T. D. Smedt
,
+7 authors
M. Moser
1999
Corpus ID: 11489794
Cells of the dendritic family display some unique properties that confer to them the capacity to sensitize naive T cells in vitro…
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Highly Cited
1999
Highly Cited
1999
Expression and kinetics of cytokines determined by intracellular staining using flow cytometry.
B. Mascher
,
Peter Schlenke
,
M. Seyfarth
JIM - Journal of Immunological Methods
1999
Corpus ID: 11938800
Highly Cited
1995
Highly Cited
1995
Regulation of immunity to malaria: valuable lessons learned from murine models.
A. Taylor-Robinson
Parasitology Today
1995
Corpus ID: 1869717
Highly Cited
1995
Highly Cited
1995
Sequential production of Th1 and Th2 cytokines in response to live bacillus Calmette-Guérin.
Birgitta Sander
,
U. Skansén‐Saphir
,
O. Damm
,
L. Hakansson
,
J. Andersson
,
U. Andersson
Immunology
1995
Corpus ID: 35784723
Causes of individual variation in susceptibility to mycobacterial diseases are only partly understood. An efficient cell-mediated…
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Review
1995
Review
1995
The role of the innate immune response in Th1 cell development following Leishmania major infection
T. Scharton‐Kersten
,
P. Scott
Journal of Leukocyte Biology
1995
Corpus ID: 2855026
Infection of mice with the protozoan parasite Leishmania major is an established model with which to study the in vivo…
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Review
1991
Review
1991
A potential role for microbial superantigens in the pathogenesis of systemic autoimmune disease.
Steven M. Friedman
,
Steven M. Friedman
,
D. Posnett
,
J. Tumang
,
Mary K. Crow
,
Barry C. Cole
Arthritis & Rheumatism
1991
Corpus ID: 21152105
We have attempted herein to demonstrate how microbial superantigens could promote an abnormal form of "cognate" T helper-B cell…
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Highly Cited
1985
Highly Cited
1985
Human lymphocyte differentiation antigens HB-10 and HB-11. II. Differential production of B cell growth and differentiation factors by distinct helper T cell subpopulations.
T. Tedder
,
M. Cooper
,
L. Clement
Journal of Immunology
1985
Corpus ID: 25505047
Two monoclonal antibodies (HB-10 and HB-11), which react with human T, B, and NK cells, identify approximately 50% of the Leu-3…
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Highly Cited
1985
Highly Cited
1985
Both L3T4+ and Lyt-2+ helper T cells initiate cytotoxic T lymphocyte responses against allogenic major histocompatibility antigens but not against trinitrophenyl-modified self
T. Mizuochi
,
H. Golding
,
A. Rosenberg
,
L. Glimcher
,
T. Malek
,
A. Singer
Journal of Experimental Medicine
1985
Corpus ID: 9225362
This study characterizes the T helper (Th) cells that initiate primary cytotoxic T lymphocyte (CTL) responses against allogeneic…
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Highly Cited
1982
Highly Cited
1982
Murine Peyer's patch T cell clones. Characterization of antigen- specific helper T cells for immunoglobulin A responses
H. Kiyono
,
J. Mcghee
,
+4 authors
S. Michalek
Journal of Experimental Medicine
1982
Corpus ID: 16579012
We successfully cloned antigen-specific T cells from murine gut- associated lymphoreticular tissue, i.e., Peyer's patches, which…
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