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T-Lymphocyte
Known as:
Lymphocytes, Thymus-Dependent
, T Cells
, Thymus-Dependent Lymphocyte
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A thymocyte-derived lymphocyte of immunological importance that is long-lived (months to years) and is responsible for cell-mediated immunity. T…
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National Institutes of Health
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Related topics
Related topics
48 relations
CAMLG protein, human
CCL1 protein, human
CCR6 protein, human
CD2 Antigens
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Narrower (9)
CD4 Positive T Lymphocytes
CD8-Positive T-Lymphocytes
Cytotoxic T-Lymphocytes
Helper-Inducer T-Lymphocyte
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Broader (1)
Lymphocyte
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Frontline: GITR, a member of the TNF receptor superfamily, is costimulatory to mouse T lymphocyte subpopulations
S. Ronchetti
,
O. Zollo
,
+5 authors
C. Riccardi
European Journal of Immunology
2004
Corpus ID: 205784004
GITR (glucocorticoid‐induced TNFR family related gene) is a member of the TNFR superfamily (TNFRSF) that is expressed in…
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Highly Cited
2003
Highly Cited
2003
Transforming Growth Factor-β Production and Myeloid Cells Are an Effector Mechanism through Which CD1d-restricted T Cells Block Cytotoxic T Lymphocyte–mediated Tumor Immunosurveillance
M. Terabe
,
S. Matsui
,
+10 authors
J. Berzofsky
Journal of Experimental Medicine
2003
Corpus ID: 1952751
Our previous work demonstrated that cytotoxic T lymphocyte (CTL)-mediated tumor immunosurveillance of the 15-12RM tumor could be…
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Highly Cited
2002
Highly Cited
2002
Origin of regulatory T cells with known specificity for antigen
I. Apostolou
,
A. Sarukhan
,
L. Klein
,
H. Boehmer
Nature Immunology
2002
Corpus ID: 31351428
T cell receptor agonists can induce the differentiation of regulatory T (TR) cells. We report here that the immunoglobulin…
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Highly Cited
2001
Highly Cited
2001
IL-7 is critical for homeostatic proliferation and survival of naïve T cells
Joyce T. Tan
,
Eric P. Dudl
,
+4 authors
C. Surh
Proceedings of the National Academy of Sciences…
2001
Corpus ID: 28006280
In T cell-deficient conditions, naïve T cells undergo spontaneous “homeostatic” proliferation in response to contact with self…
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Review
1999
Review
1999
Mature T lymphocyte apoptosis--immune regulation in a dynamic and unpredictable antigenic environment.
M. Lenardo
,
F. Chan
,
+4 authors
Lixin Zheng
Annual Review of Immunology
1999
Corpus ID: 29710026
Apoptosis of mature T lymphocytes preserves peripheral homeostasis and tolerance by countering the profound changes in the number…
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Highly Cited
1998
Highly Cited
1998
LAT The ZAP-70 Tyrosine Kinase Substrate that Links T Cell Receptor to Cellular Activation
Weiguo Zhang
,
J. Sloan-Lancaster
,
J. Kitchen
,
R. Trible
,
L. Samelson
Cell
1998
Corpus ID: 1806525
Highly Cited
1996
Highly Cited
1996
Discovery of a Novel, Potent, and Src Family-selective Tyrosine Kinase Inhibitor
J. Hanke
,
J. Gardner
,
+5 authors
P. Connelly
Journal of Biological Chemistry
1996
Corpus ID: 29832169
Here, we have studied the activity of a novel protein-tyrosine kinase inhibitor that is selective for the Src family of tyrosine…
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Highly Cited
1996
Highly Cited
1996
The human cytotoxic T-lymphocyte (CTL) response to cytomegalovirus is dominated by structural protein pp65: frequency, specificity, and T-cell receptor usage of pp65-specific CTL
M. Wills
,
A. Carmichael
,
+4 authors
J. Sissons
Journal of Virology
1996
Corpus ID: 25184407
Cytotoxic T lymphocytes (CTL) appear to play an important role in the control of human cytomegalovirus (HCMV) in the normal virus…
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Highly Cited
1995
Highly Cited
1995
Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton
S. Valitutti
,
M. Dessing
,
K. Aktories
,
H. Gallati
,
A. Lanzavecchia
Journal of Experimental Medicine
1995
Corpus ID: 1892894
Using antigen-specific T cell clones and peptide-pulsed antigen- presenting cells (APCs) we investigated the mechanisms that lead…
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Highly Cited
1984
Highly Cited
1984
Voltage-gated K+ channels in human T lymphocytes: a role in mitogenesis?
T. DeCoursey
,
K. Chandy
,
Sudhir Gupta
,
M. Cahalan
Nature
1984
Corpus ID: 4340921
Membrane receptors and ion transport mechanisms probably have an important role in lymphocyte activation leading to T-lymphocyte…
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