CCL1 protein, human

Known as: Small-Inducible Cytokine A1, CCL1, chemokine I-309, human 
C-C motif chemokine 1 (96 aa, ~11 kDa) is encoded by the human CCL1 gene. This protein is involved in monocyte chemotaxis.
National Institutes of Health

Related topics

Related topics

18 relations
Biologic DevelopmentCCL1 geneCCL1 wt AlleleCentral Nervous System
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Broader (1)

Chemokine CCL1

Narrower (1)

Recombinant I-309

Papers overview

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Highly Cited
2011
Highly Cited
2011
A striking local esophageal cytokine expression profile in eosinophilic esophagitis.
BACKGROUND Eosinophilic esophagitis (EE) is an emerging worldwide disease that mimics gastroesophageal reflux disease… (More)
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2010
2010
Blockade of CCL1 inhibits T regulatory cell suppressive function enhancing tumor immunity without affecting T effector responses.
Intratumoral accumulation of T regulatory cells (Tregs) creates an immunosuppressive environment that reduces the efficacy of… (More)
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Highly Cited
2006
Highly Cited
2006
Differential regulation of chemokine production by Fcgamma receptor engagement in human monocytes: association of CCL1 with a distinct form of M2 monocyte activation (M2b, Type 2).
CC chemokine ligand 1 (CCL1; I-309) is a CC chemokine that interacts with CC chemokine receptor 8, which is preferentially… (More)
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Highly Cited
2003
Highly Cited
2003
Release of both CCR4-active and CXCR3-active chemokines during human allergic pulmonary late-phase reactions.
BACKGROUND Segmental antigen bronchoprovocation has long been used as a model to study allergic pulmonary inflammatory responses… (More)
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2002
2002
Skin-homing CLA+ T cells and regulatory CD25+ T cells represent major subsets of human peripheral blood memory T cells migrating in response to CCL1/I-309.
Functionally distinct T cell subsets exhibit specific chemokine receptor profiles that regulate their tissue localization. Here… (More)
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2002
2002
Kin28 is found within TFIIH and a Kin28-Ccl1-Tfb3 trimer complex with differential sensitivities to T-loop phosphorylation.
Basal transcription factor TFIIH phosphorylates the RNA polymerase II (RNApII) carboxy-terminal domain (CTD) within the… (More)
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2002
2002
Expression of T lymphocyte chemoattractants and activation markers in vernal keratoconjunctivitis.
BACKGROUND/AIMS T lymphocytes are present in increased numbers in the conjunctiva of patients with vernal keratoconjunctivitis… (More)
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Highly Cited
1999
Highly Cited
1999
Chemokine and chemokine receptor expression in a novel human mesangial cell line.
Chemokines are thought to play a pivotal role in mediating the selective migration of leukocytes into sites of tissue injury. The… (More)
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Highly Cited
1997
Highly Cited
1997
Identification of CCR8: A Human Monocyte and Thymus Receptor for the CC Chemokine I-309
The human CC chemokine I-309 is a potent monocyte chemoattractant and inhibits apoptosis in thymic cell lines. Here, we identify… (More)
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1992
1992
The human cytokine I-309 is a monocyte chemoattractant.
The human cytokine I-309 is a small glycoprotein secreted by activated T lymphocytes and structurally related to a number of… (More)
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