Cytotoxic T-Lymphocytes

Known as: Killer T cell, Cytotoxic T lymphocyte, Cell Mediated Lympholytic Cells 
Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed… (More)

Topic mentions per year

Topic mentions per year

1962-2018
0500100019622018

Papers overview

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Review
2016
Review
2016
Interleukin-10 (IL-10) is known to be a tolerogenic cytokine since it inhibits pro-inflammatory cytokine production and T cell… (More)
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Highly Cited
2003
Highly Cited
2003
A long-standing paradox in cellular immunology concerns the conditional requirement for CD4+ T-helper (T(H)) cells in the priming… (More)
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Highly Cited
2003
Highly Cited
2003
Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) is a critical immunoregulatory molecule (expressed on activated T cells and… (More)
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Highly Cited
2000
Highly Cited
2000
This report shows that cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) plays a key role in T cell-mediated dominant… (More)
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Highly Cited
1998
Highly Cited
1998
Although in vivo priming of CD8+ cytotoxic T lymphocytes (CTLs) generally requires the participation of CD4+ T-helper lymphocytes… (More)
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Highly Cited
1998
Highly Cited
1998
Cytotoxic T lymphocytes (CTLs) which carry the CD8 antigen recognize antigens that are presented on target cells by the class I… (More)
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Highly Cited
1998
Highly Cited
1998
Cytotoxic T lymphocytes (CTLs) lyse virally infected cells that display viral peptide epitopes in association with major… (More)
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Highly Cited
1997
Highly Cited
1997
The precise role played by HIV-specific cytotoxic T lymphocytes (CTL) in HIV infection remains controversial. Despite strong CTL… (More)
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Highly Cited
1996
Highly Cited
1996
It is widely believed that viral clearance is mediated principally by the destruction of infected cells by CTLs. In this report… (More)
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Highly Cited
1994
Highly Cited
1994
Human immunodeficiency virus type 1 (HIV-1) Env-, Gag-, Pol-, Nef-, and Tat-specific cytotoxic T-lymphocyte (CTL) activities were… (More)
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