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Cytotoxic T-Lymphocytes

Known as: Killer T cell, Cytotoxic T lymphocyte, Cell Mediated Lympholytic Cells 
Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed… Expand
National Institutes of Health

Related topics

Related topics

50 relations
2G-1 TCR Retroviral Vector-Transduced LymphocytesActivated Marrow Infiltrating LymphocytesAd5-survivin-transduced Autologous Dendritic Cell VaccineAgonistic Anti-OX40 Monoclonal Antibody MEDI6383
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Next generation of immune checkpoint therapy in cancer: new developments and challenges
Immune checkpoints consist of inhibitory and stimulatory pathways that maintain self-tolerance and assist with immune response… Expand
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Review
2018
Review
2018
Direct-Acting Antiviral Prophylaxis in Kidney Transplantation From Hepatitis C VirusInfected Donors to Noninfected Recipients
More than 420000 persons in the United States require hemodialysis for end-stage kidney disease (1). These patients face a high… Expand
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Review
2018
Review
2018
Mechanistic overview of immune checkpoints to support the rational design of their combinations in cancer immunotherapy.
Checkpoint receptor blockers, known to act by blocking the pathways that inhibit immune cell activation and stimulate immune… Expand
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Review
2018
Review
2018
Cancer immunotherapy beyond immune checkpoint inhibitors
Malignant cells have the capacity to rapidly grow exponentially and spread in part by suppressing, evading, and exploiting the… Expand
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Review
2017
Review
2017
Dermatologic Reactions to Immune Checkpoint Inhibitors
  • Vincent Sibaud
  • American Journal of Clinical Dermatology
  • 2017
    • Corpus ID: 2401625
The development of immune checkpoint inhibitors [monoclonal antibodies targeting cytotoxic T lymphocyte-associated antigen-4… Expand
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Review
2017
Review
2017
Cardiotoxicity of immune checkpoint inhibitors
Cardiac toxicity after conventional antineoplastic drugs (eg, anthracyclines) has historically been a relevant issue. In addition… Expand
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Review
2017
Review
2017
Cytokines in immunogenic cell death: Applications for cancer immunotherapy
&NA; Despite advances in treatments like chemotherapy and radiotherapy, metastatic cancer remains a leading cause of death for… Expand
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Review
2017
Review
2017
Dendritic cells based immunotherapy.
Dendritic cells (DCs) are the most potent antigen-presenting cells, and tumor antigen-loaded DCs (DC-vaccines) can activate tumor… Expand
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Review
2017
Review
2017
Immune checkpoint inhibitors in advanced renal cell carcinoma: experience to date and future directions.
In recent years, there has been dramatic expansion of the treatment armamentarium for patients with advanced renal cell carcinoma… Expand
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Review
2017
Review
2017
Adverse Renal Effects of Immune Checkpoint Inhibitors: A Narrative Review
Background: Cancer immunotherapy, such as anti-cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and anti-programmed death 1… Expand
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