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Cytotoxic T-Lymphocytes

Known as: Killer T cell, Cytotoxic T lymphocyte, Cell Mediated Lympholytic Cells 
Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed… 
National Institutes of Health

Related topics

Related topics

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2G-1 TCR Retroviral Vector-Transduced LymphocytesActivated Marrow Infiltrating LymphocytesAd5-survivin-transduced Autologous Dendritic Cell VaccineAgonistic Anti-OX40 Monoclonal Antibody MEDI6383

Papers overview

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Highly Cited
1989
Highly Cited
1989
Mechanism of action of 15-deoxyspergualin. I. Suppressive effect on the induction of alloreactive secondary cytotoxic T lymphocytes in vivo and in vitro.
The effects of 15-deoxyspergualin (DSG) and its derivative deoxymethylspergualin (MeDSG), which is more stable than DSG in… 
1987
1987
Physiological changes induced in cardiac myocytes by cytotoxic T lymphocytes.
The "lethal hit" induced by viral specific, sensitized, cytotoxic T lymphocytes (CTL) attacking virus-infected heart cells is… 
1986
1986
The mitogenic activity of staphylococcal enterotoxin B (SEB): a monovalent T cell mitogen that stimulates cytolytic T lymphocytes but cannot mediate their lytic interaction.
Staphylococcal enterotoxin B (SEB), a monovalent T cell mitogen and inducer of T suppressor cells, was found to be a potent… 
Highly Cited
1984
Highly Cited
1984
Malignant growth in the normal host after variant selection in vitro with cytolytic T-cell lines.
Using variant selection in vitro, we have explored the changes necessary to convert potentially malignant cells into… 
Highly Cited
1984
Highly Cited
1984
Biology of cloned cytotoxic T lymphocytes specific for lymphocytic choriomeningitis virus. I. Generation and recognition of virus strains and H-2b mutants.
Cytotoxic T lymphocytes (CTL) were induced in C57BL/6 and (C57BL/6 X DBA/2)F1 mice after immunization with the Armstrong strain… 
1984
1984
FREQUENCY ANALYSIS OF CYCLOSPORINE‐SENSITIVE CYTOTOXIC T LYMPHOCYTE PRECURSORS
The influence of the immunosuppressant cyclosporine (CsA) on the antigen-driven activation of resting cytotoxic T lymphocyte… 
1983
1983
Depletion of human NK cells with monoclonal antibodies allows the generation of cytotoxic T lymphocytes without NK-like cells in mixed cultures.
In vitro stimulation of human mononuclear cells with x-irradiated autologous lymphoblastoid cell line (LCL) or allogeneic normal… 
Highly Cited
1981
Highly Cited
1981
Studies on T cell subsets and functions in leprosy.
T cell subsets and T cell functions were explored in 31 leprosy patients with the following methods: determination of the… 
1979
1979
Function and Structure of the Immune System
A significant in vivo activation of cytotoxic T-Iymphocytes (CTL) against trinitrophenyl (TNP)-modified autologous cells and of a… 
1976
1976
Effects of Tumor-like assay conditions, lonizing radiation, and hyperthermia on immune lysis of tumor cells by cytotoxic T-lymphocytes.
Cytotoxic T-lymphocytes (CTL's) harvested from mixed splenic lymphocyte cultures (DBA/2 + C57BL) were tested for their ability to…