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Cytotoxic T-Lymphocytes

Known as: Killer T cell, Cytotoxic T lymphocyte, Cell Mediated Lympholytic Cells 
Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed… Expand
National Institutes of Health

Related topics

Related topics

50 relations
2G-1 TCR Retroviral Vector-Transduced LymphocytesActivated Marrow Infiltrating LymphocytesAd5-survivin-transduced Autologous Dendritic Cell VaccineAgonistic Anti-OX40 Monoclonal Antibody MEDI6383
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Combination of CTLA-4 and PD-1 blockers for treatment of cancer
  • A. Rotte
  • Journal of experimental & clinical cancer…
  • 2019
    • Corpus ID: 189817689
Targeting checkpoints of immune cell activation has been demonstrated to be the most effective approach for activation of anti… Expand
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Review
2019
Review
2019
CD8+ cytotoxic T lymphocytes in cancer immunotherapy: A review
CD8+ cytotoxic T lymphocytes (CTLs) are preferred immune cells for targeting cancer. During cancer progression, CTLs encounter… Expand
Review
2019
Review
2019
Regulatory T cells in cancer immunosuppression — implications for anticancer therapy
Regulatory T (Treg) cells, an immunosuppressive subset of CD4+ T cells characterized by the expression of the master… Expand
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Review
2019
Review
2019
Immune checkpoint inhibitor-induced colitis: A comprehensive review
Immune checkpoint inhibitors (ICIs) are monoclonal antibodies that target down-regulators of the anti-cancer immune response… Expand
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Review
2019
Review
2019
A Systematic Review and Meta-Analysis of Endocrine-Related Adverse Events Associated with Immune Checkpoint Inhibitors.
Monoclonal antibodies targeting cytotoxic T-lymphocyte antigen-4 (CTLA-4), programed cell death 1 (PD-1), or its ligand (PD-L1… Expand
Review
2019
Review
2019
Cardiovascular toxicities associated with immune checkpoint inhibitors
Cardiovascular toxicities associated with immune checkpoint inhibitors (ICIs) have been reported in case series but have been… Expand
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Review
2019
Review
2019
Contribution of regulatory T cells to cancer: A review
Regulatory T cells (Tregs) represent a low number of T‐cell population under normal conditions, and they play key roles for… Expand
Review
2018
Review
2018
CD4+ T cell help in cancer immunology and immunotherapy
Cancer immunotherapy aims to promote the activity of cytotoxic T lymphocytes (CTLs) within a tumour, assist the priming of tumour… Expand
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Review
2018
Review
2018
Exosome‐mediated regulation of tumor immunology
Exosomes are representative extracellular vesicles (EV) derived from multivesicular endosomes (MVE) and have been described as… Expand
Review
2018
Review
2018
Notch Signaling as a Regulator of the Tumor Immune Response: To Target or Not To Target?
The Notch signaling pathway regulates important cellular processes involved in stem cell maintenance, proliferation, development… Expand
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