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Cytotoxic T-Lymphocytes

Known as: Killer T cell, Cytotoxic T lymphocyte, Cell Mediated Lympholytic Cells 
Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed… 
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
A long-standing paradox in cellular immunology concerns the conditional requirement for CD4+ T-helper (TH) cells in the priming… 
Highly Cited
2001
Highly Cited
2001
Therapeutic efficacy of a tumor cell–based vaccine against experimental B16 melanoma requires the disruption of either of two… 
Highly Cited
2000
Highly Cited
2000
This report shows that cytotoxic T lymphocyte–associated antigen 4 (CTLA-4) plays a key role in T cell–mediated dominant… 
Highly Cited
2000
Highly Cited
2000
It is now clear that functionally specialized regulatory T (Treg) cells exist as part of the normal immune repertoire, preventing… 
Highly Cited
1998
Highly Cited
1998
Although in vivo priming of CD8+ cytotoxic T lymphocytes (CTLs) generally requires the participation of CD4+ T-helper lymphocytes… 
Highly Cited
1998
Highly Cited
1998
Cytotoxic T lymphocytes (CTLs) which carry the CD8 antigen recognize antigens that are presented on target cells by the class I… 
Highly Cited
1998
Highly Cited
1998
Cytotoxic T lymphocytes (CTLs) lyse virally infected cells that display viral peptide epitopes in association with major… 
Highly Cited
1997
Highly Cited
1997
The precise role played by HIV-specific cytotoxic T lymphocytes (CTL) in HIV infection remains controversial. Despite strong CTL… 
Highly Cited
1997
Highly Cited
1997
The HIV-1-specific cytotoxic T lymphocyte (CTL) response is temporally associated with the decline in viremia during primary HIV… 
Highly Cited
1996
Highly Cited
1996
Identification and characterization of antigen-specific T lymphocytes during the course of an immune response is tedious and…