CD8-Positive T-Lymphocytes

Known as: Lymphocyte, CD8-Positive, CD8+ T-Lymphocyte, CD8-Positive Lymphocytes 
A critical subpopulation of regulatory T-lymphocytes involved in MHC Class I-restricted interactions. They include both cytotoxic T-lymphocytes (T… (More)
National Institutes of Health

Papers overview

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2014
2014
Immunotherapies that augment antitumor T cells have had recent success for treating patients with cancer. Here we examined… (More)
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Review
2011
Review
2011
Cytotoxic CD8 T lymphocytes (CTLs) play a pivotal role in the control of infection. Activated CTLs, however, often lose effector… (More)
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Highly Cited
2010
Highly Cited
2010
An effective HIV vaccine must elicit immune responses that recognize genetically diverse viruses. It must generate CD8+ T… (More)
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Highly Cited
2009
Highly Cited
2009
CD4 T helper cells are well known for their role in providing critical signals during priming of cytotoxic CD8 T lymphocyte (CTL… (More)
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Highly Cited
2007
Highly Cited
2007
In humans, the pathways of memory and effector T cell differentiation remain poorly defined. We have dissected the functional… (More)
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Highly Cited
2007
Highly Cited
2007
"Elite controllers" are individuals that durably control human immunodeficiency virus or simian immunodeficiency virus… (More)
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2006
2006
TLR are evolutionarily conserved molecules that play a key role in the initiation of innate antimicrobial immune responses… (More)
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Highly Cited
2004
Highly Cited
2004
The T-box transcription factor T-bet is known to control lineage commitment and interferon-gamma production by T helper 1 (Th1… (More)
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Highly Cited
2003
Highly Cited
2003
A long-standing paradox in cellular immunology concerns the conditional requirement for CD4+ T-helper (TH) cells in the priming… (More)
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Highly Cited
2001
Highly Cited
2001
CD8(+) T cells use a number of effector mechanisms to protect the host against infection. We have studied human CD8(+) T cells… (More)
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