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CD8-Positive T-Lymphocytes

Known as: Lymphocyte, CD8-Positive, CD8+ T-Lymphocyte, CD8-Positive Lymphocytes 
A critical subpopulation of regulatory T-lymphocytes involved in MHC Class I-restricted interactions. They include both cytotoxic T-lymphocytes (T… 
National Institutes of Health

Related topics

Related topics

31 relations
CD4/CD8 ratio procedureCD40 Ligand, humanCD8 AntigensCarcinoembryonic Antigen

Narrower (3)

Cytotoxic T-LymphocytesSuppressor T LymphocyteSuppressor T-Lymphocytes, CD8-Positive

Broader (2)

T-LymphocyteT-Lymphocyte Subsets

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Tumor-specific CD4+ T cells maintain effector and memory tumor-specific CD8+ T cells
Immunotherapies that augment antitumor T cells have had recent success for treating patients with cancer. Here we examined… 
Highly Cited
2004
Highly Cited
2004
Detection of T-cell degranulation: CD107a and b.
Highly Cited
2004
Highly Cited
2004
T-bet Controls Autoaggressive CD8 Lymphocyte Responses in Type 1 Diabetes
The T-box transcription factor T-bet is known to control lineage commitment and interferon-γ production by T helper 1 (Th1) CD4… 
Highly Cited
2003
Highly Cited
2003
Essential role for ICSBP in the in vivo development of murine CD8alpha + dendritic cells.
Interferon (IFN) consensus sequence-binding protein (ICSBP) is an important transcription factor regulating proinflammatory… 
Highly Cited
1997
Highly Cited
1997
A naturally occurring mutant human epidermal growth factor receptor as a target for peptide vaccine immunotherapy of tumors.
The type III EGF receptor (EGFRvIII) is the result of an in-frame deletion from nucleotides 275 to 1075 in the EGF receptor cDNA… 
Highly Cited
1997
Highly Cited
1997
Identification of Trypanosoma cruzi trans-sialidase family members as targets of protective CD8+ TC1 responses.
CD8+ T lymphocytes play a critical role in immunity to Trypanosoma cruzi. However, the target molecules of this T cell subset… 
Highly Cited
1995
Highly Cited
1995
Cytotoxic T cells specific for a single peptide on the M2 protein of respiratory syncytial virus are the sole mediators of resistance induced by immunization with M2 encoded by a recombinant vaccinia…
We have studied the immunobiology of respiratory syncytial virus (RSV), a major cause of respiratory tract morbidity in children… 
Highly Cited
1994
Highly Cited
1994
Different use of T cell receptor transducing modules in two populations of gut intraepithelial lymphocytes are related to distinct pathways of T cell differentiation
Most gut intraepithelial cells (IEL) of the mouse are T cells that bear CD8 molecules, present either as alpha-beta chain… 
Highly Cited
1989
Highly Cited
1989
Direct evidence for binding of CD8 to HLA class I antigens
Adhesion of T lymphocytes is an essential step for antigen recognition and lymphocyte activation. mAbs to T cell surface proteins… 
Highly Cited
1989
Highly Cited
1989
Elimination of CD4+ suppressor T cells from susceptible BALB/c mice releases CD8+ T lymphocytes to mediate protective immunity against Leishmania
This study examined the capacity of BALB/c mice that had been depleted of T cell subpopulations to generate a protective immune… 
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