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CD8 Antigens

Known as: T8 molecule, T8 Antigens, T Cell, Leu-2 Antigens 
Differentiation antigens found on thymocytes and on cytotoxic and suppressor T-lymphocytes. CD8 antigens are members of the immunoglobulin supergene… 
National Institutes of Health

Related topics

Related topics

16 relations

Broader (1)

CD Antigens
CD4/CD8 ratio procedureCD8 Ag:PrThr:Pt:Tiss:Ord:Immune stainCD8 Antigen, Beta Polypeptide 1CD8-Positive T-Lymphocytes

Narrower (5)

CD8 antigen, alpha chainCD8alpha antigenCD8alphabeta antigenCD8beta antigen, rat

Papers overview

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2010
2010
p300-Mediated Acetylation Stabilizes the Th-Inducing POK Factor
The lineage-specifying factor Th-inducing POK (ThPOK) directs the intrathymic differentiation of CD4 T cells. Although the… 
2007
2007
Regulation of allergen‐induced bone marrow eosinophilopoiesis: role of CD4+ and CD8+ T cells
Background:  The mechanisms of the distant stimulation of the bone marrow (BM) after airway allergen exposure remain largely… 
2003
2003
Activation of Alloreactive CD8+ T Cells Operates Via CD4-Dependent and CD4-Independent Mechanisms and Is CD154 Blockade Sensitive 1
CD154, one of the most extensively studied T cell costimulation molecules, represents a promising therapeutic target in organ… 
2001
2001
Intensive generation of NK1.1– extrathymic T cells in the liver by injection of bone marrow cells isolated from mice with a mutation of polymorphic major histocompatibility complex antigens
Whether intermediate TCR (TCRint) cells and natural killer T (NKT or NK1.1+TCRint) cells are extrathymically generated remains… 
1994
1994
A high alpha-linolenate diet suppresses antigen-induced immunoglobulin E response and anaphylactic shock in mice.
Mice were fed for 2 mo diets having ratios of alpha-linolenate [18:3 (n-3)] to linoleate [18:2(n-6)] of < 0.01, 0.36, 1.0 and 3.9… 
1988
1988
Gene transfer of the ly‐3 chain gene of the mouse cd8 molecular complex: co‐transfer with the ly‐2 polypeptide gene results in detectable cell surface expression of the ly‐3 antigenic determinants
The CD8 molecule is a glycoprotein expressed on a subset of mature T lymphocytes. It has been postulated to be a receptor for… 
1988
1988
Development of an antigen-specific CD8 suppressor effector clone in man.
A long-term cultured IL-2-dependent keyhole limpet hemocyanin (KLH)-specific CD8 (T8) suppressor clone (5B9) was generated from a… 
1986
1986
Striking similarities between antigen receptor J pieces and sequence in the second chain of the murine CD8 antigen
The CD8 antigen is a marker for T-lymphocyte subsets that is absent from helper T cells but expressed on cytotoxic T cells which… 
1986
1986
Evidence for a regulatory role of the T8 (CD8) antigen in antigen‐specific and anti‐T3‐(CD3)‐induced lytic activity of allospecific cytotoxic T lymphocyte clones
The functional role of the T8 antigen of human T cells was studied by inhibition with anti‐T8 monoclonal antibodies (mAb) of the… 
1983
1983
Binding of phosphatidylethanolamine and phosphatidylinositol to OKT8+ lymphocytes activates suppressor cell activity.
The phospholipids phosphatidylethanolamine (PE) and phosphatidylinositol (PI) have been shown to activate a population of OKT8… 
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