CD8 Antigens

Known as: T8 molecule, T8 Antigens, T Cell, Leu-2 Antigens 
Differentiation antigens found on thymocytes and on cytotoxic and suppressor T-lymphocytes. CD8 antigens are members of the immunoglobulin supergene… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1982-2018
051019822018

Papers overview

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Highly Cited
2010
Highly Cited
2010
Peripheral immune tolerance is generally thought to result from cross-presentation of tissue-derived proteins by quiescent tissue… (More)
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Highly Cited
2007
Highly Cited
2007
Tumor-infiltrating cytotoxic T lymphocytes (TILs), including CD8 TILs, have been associated with favorable clinical outcomes in… (More)
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Highly Cited
2007
Highly Cited
2007
Of the many dendritic cell (DC) subsets, DCs expressing the monomorphic coreceptor CD8 α-chain (CD8α) are localized permanently… (More)
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Highly Cited
2005
Highly Cited
2005
In a recent report, [Zhang et al. (2003) N. Engl. J. Med. 348, 203-213], the presence of CD3+ tumor-infiltrating lymphocytes… (More)
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Highly Cited
2002
Highly Cited
2002
To prevent bystander destruction of healthy host tissues, cytotoxic CD8+ T lymphocytes are fitted with specific receptors that… (More)
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Highly Cited
2001
Highly Cited
2001
CD4 T-cell help is required during the generation and maintenance of effective antitumor CD8 T cell-mediated immunity. The goal… (More)
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Highly Cited
1998
Highly Cited
1998
Cytotoxic T lymphocytes (CTLs) which carry the CD8 antigen recognize antigens that are presented on target cells by the class I… (More)
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Highly Cited
1992
Highly Cited
1992
A new procedure for rapid isolation of dendritic cells (DC) was devised, involving collagenase digestion of tissues, dissociation… (More)
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Highly Cited
1988
Highly Cited
1988
In recent malaria sporozoite vaccine trials in humans and mice, antibodies to the sporozoite coat protein have given only modest… (More)
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Highly Cited
1987
Highly Cited
1987
This study was designed to test the hypothesis that T-cell effector mechanisms are required for protective immunity to malaria… (More)
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