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CD8 Antigens

Known as: T8 molecule, T8 Antigens, T Cell, Leu-2 Antigens 
Differentiation antigens found on thymocytes and on cytotoxic and suppressor T-lymphocytes. CD8 antigens are members of the immunoglobulin supergene… 
National Institutes of Health

Related topics

Related topics

16 relations

Broader (1)

CD Antigens
CD4/CD8 ratio procedureCD8 Ag:PrThr:Pt:Tiss:Ord:Immune stainCD8 Antigen, Beta Polypeptide 1CD8-Positive T-Lymphocytes

Narrower (5)

CD8 antigen, alpha chainCD8alpha antigenCD8alphabeta antigenCD8beta antigen, rat

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
p300-Mediated Acetylation Stabilizes the Th-Inducing POK Factor
The lineage-specifying factor Th-inducing POK (ThPOK) directs the intrathymic differentiation of CD4 T cells. Although the… 
Highly Cited
2005
Highly Cited
2005
Consequences of Immunodominant Epitope Deletion for Minor Influenza Virus-Specific CD8+-T-Cell Responses
ABSTRACT The extent to which CD8+ T cells specific for other antigens expand to compensate for the mutational loss of the… 
Highly Cited
2003
Highly Cited
2003
CD8α+ mouse spleen dendritic cells do not originate from the CD8α- dendritic cell subset
Although previous studies had indicated that the CD8α- and CD8α+ subtypes of murine dendritic cells (DCs) differ in immediate… 
2000
2000
Mouse CD8+ CD122+ T Cells with Intermediate TCR Increasing with Age Provide a Source of Early IFN-γ Production
Although CD8+ IL-2Rβ (CD122)+ T cells with intermediate TCR reportedly develop extrathymically, their functions still remain… 
1995
1995
Lack of evidence of HTLV-I/II infection in T CD8 malignant or reactive lymphoproliferative disorders in France: a serological and/or molecular study of 169 cases.
Human T lymphotropic virus type II (HTLV-II), originally isolated in 1982 from a patient with a "T hairy cell leukemia", has not… 
Highly Cited
1994
Highly Cited
1994
Lymphocyte activation in HIV‐1 infection. II. Functional defects of CD28− T cells
Objectives and design:The expression of the accessory molecule CD28 was compared in various populations of T and natural killer… 
1993
1993
Polymorphism in the mouse Tap-1 gene. Association with abnormal CD8+ T cell development in the nonobese nondiabetic mouse.
Tap-1 and Tap-2 genes code for a heterodimeric peptide transporter required for the normal maturation and surface expression of… 
1991
1991
Serum soluble CD8 molecule is a marker of CD8 T-cell activation in HIV-1 disease.
To characterize CD8 T-cell activation during HIV-1 infection we measured serum soluble CD8 (sCD8) levels longitudinally in… 
Highly Cited
1990
Highly Cited
1990
Effector mechanisms in cyclosporine A-induced syngeneic graft-versus-host disease. Role of CD4+ and CD8+ T lymphocyte subsets.
Syngeneic graft-versus-host disease (SGVHD) is a T cell-mediated autoimmune disease occurring postsyngeneic bone marrow… 
Highly Cited
1984
Highly Cited
1984
Isolation of the gene encoding the human T-lymphocyte differentiation antigen Leu-2 (T8) by gene transfer and cDNA subtraction.
We report the isolation of genomic and cDNA clones encoding the human T-lymphocyte cell-surface differentiation antigen, Leu-2… 
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