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CD8 Antigen, Beta Polypeptide 1

Known as: CD8B, T-Cell Surface Glycoprotein CD8 Beta Chain, LYT3 
T-cell surface glycoprotein CD8 beta chain (210 aa, ~24 kDa) is encoded by the human CD8B gene. This protein plays a role in T-cell cytotoxicity.
National Institutes of Health

Related topics

Related topics

15 relations
CD8 AntigensCD8A geneCD8B geneCD8B wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Neutrophil expansion defines an immunoinhibitory peripheral and intratumoral inflammatory milieu in resected non-small cell lung cancer: a descriptive analysis of a prospectively immunoprofiled…
Background The biological underpinnings of the prognostic and predictive significance of a relative neutrophilia in patients with… 
2020
2020
Single or Combined Dietary Supply of Psidium guajava and Phyllanthus amarus Extracts Differentially Modulate Immune Responses and Liver Proteome in Striped Catfish (Pangasianodon hyphophthalmus)
Guava Psidium guajava L (Pg) and bhumi amla Phyllanthus amarus Schum. et Thonn (Pa) are well-known plants in traditional medicine… 
Highly Cited
2015
Highly Cited
2015
Transcriptomic correlates of organ failure extent in sepsis.
2015
2015
The DNA methylation signature of human TCRαβ+CD4-CD8- double negative T cells reveals CG demethylation and a unique epigenetic architecture permissive to a broad stimulatory immune response.
2014
2014
Transcriptome analysis reveals an activation of major histocompatibility complex 1 and 2 pathways in chicken trachea immunized with infectious laryngotracheitis virus vaccine.
Infectious laryngotracheitis is an acute, contagious, upper respiratory disease of chickens caused by gallid herpes virus 1. Due… 
Review
2011
Review
2011
The golden anniversary of the thymus
Nature Reviews Immunology 11, 489–495 (2011) In the original version of this article, in the section under the title “Lymphocyte… 
Highly Cited
2006
Highly Cited
2006
Negative regulation of CD8 expression via Cd8 enhancer–mediated recruitment of the zinc finger protein MAZR
Coreceptor expression is tightly regulated during thymocyte development. Deletion of specific Cd8 enhancers leads to variegated… 
2004
2004
Identification of key immune mediators regulating T helper 1 responses in swine.
Review
2002
Review
2002
Decision making in the immune system: Chromatin and CD4, CD8A and CD8B gene expression during thymic differentiation
The regulation of gene expression during thymocyte development provides an ideal experimental system to study lineage-commitment… 
1983
1983
Phenotypes of human large granular lymphocytes as defined by monoclonal antibodies.
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