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CD8 Antigen, Beta Polypeptide 1

Known as: CD8B, T-Cell Surface Glycoprotein CD8 Beta Chain, LYT3 
T-cell surface glycoprotein CD8 beta chain (210 aa, ~24 kDa) is encoded by the human CD8B gene. This protein plays a role in T-cell cytotoxicity.
National Institutes of Health

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Related topics

15 relations
CD8 AntigensCD8A geneCD8B geneCD8B wt Allele
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Papers overview

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2016
2016
The Impact of HIV Co-Infection on the Genomic Response to Sepsis
HIV patients have an increased risk to develop sepsis and HIV infection affects several components of the immune system involved… Expand
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2015
2015
Transcriptomic correlates of organ failure extent in sepsis.
OBJECTIVES Sepsis is characterised by the frequent presence of organ failure and marked immunologic alterations. We studied the… Expand
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2015
2015
The DNA methylation signature of human TCRαβ+CD4-CD8- double negative T cells reveals CG demethylation and a unique epigenetic architecture permissive to a broad stimulatory immune response.
T cell receptor (TCR) αβ+CD4-CD8- double negative T cells represent a rare T cell subset implicated in the pathogenesis of… Expand
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2014
2014
Transcriptome analysis reveals an activation of major histocompatibility complex 1 and 2 pathways in chicken trachea immunized with infectious laryngotracheitis virus vaccine.
Infectious laryngotracheitis is an acute, contagious, upper respiratory disease of chickens caused by gallid herpes virus 1. Due… Expand
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2007
2007
Treatment of mycosis fungoides by recombinant leukocyte alpha — A interferon and vinblastine
Hairy-cel l leukemia is a B-cel l tumor in which IFN-~has recent ly been shown to have a clear antitumor ef fect . In order to… Expand
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2007
2007
Efficacy of gamma and alpha interferon (IFN) in the treatment of hairy cell leukemia (HCL)
Hairy-cel l leukemia is a B-cel l tumor in which IFN-~has recent ly been shown to have a clear antitumor ef fect . In order to… Expand
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Highly Cited
2006
Highly Cited
2006
Negative regulation of CD8 expression via Cd8 enhancer–mediated recruitment of the zinc finger protein MAZR
Coreceptor expression is tightly regulated during thymocyte development. Deletion of specific Cd8 enhancers leads to variegated… Expand
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2004
2004
Identification of key immune mediators regulating T helper 1 responses in swine.
This publication describes the cloning of full or partial length sequences for pig TBX21 (T-bet), MYD88, ICSBP1, CD8A (CD8alpha… Expand
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2004
2004
Evaluation of the circulating and splenic lymphocyte subpopulations in patients with non-hodgkin lymphomas and Hodgkin's disease using monoclonal antibodies
SummaryThe number of B lymphocytes, T lymphocytes and their helper/inducer, cytotoxic/suppressor and NK/K subpopulations was… Expand
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1983
1983
Phenotypes of human large granular lymphocytes as defined by monoclonal antibodies.
Four monoclonal antibodies VEP8, VEP9, VIM-D5, VIB-C5 against antigens expressed on human mature myeloid cells (polymorphonuclear… Expand
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