CD 8 a 1 and CD 8 a 2 Subclasses of Dendritic Cells Direct the Development of Distinct T Helper Cells In Vivo

@inproceedings{MaldonadoLpez1999CD8A,
  title={CD 8 a 1 and CD 8 a 2 Subclasses of Dendritic Cells Direct the Development of Distinct T Helper Cells In Vivo},
  author={By Roberto Maldonado-L{\'o}pez and Thibaut De Smedt and Patrick Michel and Jacques Godfroid and Bernard Pajak and Carlo Heirman and Kris 8 Thielemans and Oberdan Leo and Jacques Urbain and M. G. Moser},
  year={1999}
}
Cells of the dendritic family display some unique properties that confer to them the capacity to sensitize naive T cells in vitro and in vivo. In the mouse, two subclasses of dendritic cells (DCs) have been described that differ by their CD8 a expression and their localization in lymphoid organs. The physiologic function of both cell populations remains obscure. Studies conducted in vitro have suggested that CD8 a 1 DCs could play a role in the regulation of immune responses, whereas… CONTINUE READING

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