FAQ

Hepatitis A Virus Cellular Receptor 2

Known as: CD366 Antigen, HAVCR2, T Cell Immunoglobulin Mucin 3 
An Ig domain-containing membrane receptor that is expressed by TH1 CELLS. It regulates the activation of MACROPHAGES and inhibits TH1-mediated auto… (More)

Topic mentions per year

Topic mentions per year

2005-2017
05101520052017

Related topics

Related topics

16 relations
HAVCR2 geneImmune System ProcessesImmune ToleranceImmunoglobulin Domains
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Hepatitis A Virus Cellular Receptor 2
Plasma membrane
physiological aspects
agonists
T-Cell Activation
Immune System Processes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Immunoregulation of dendritic cells by the receptor T cell Ig and mucin protein-3 via Bruton's tyrosine kinase and c-Src.
The receptor T cell Ig and mucin protein-3 (TIM-3) has emerged as an important regulator of innate immune responses. However… (More)
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2013
2013
TIM-3 Does Not Act as a Receptor for Galectin-9
T cell immunoglobulin and mucin protein 3 (TIM-3) is a type I cell surface protein that was originally identified as a marker for… (More)
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2013
2013
Combined TIM-3 blockade and CD137 activation affords the long-term protection in a murine model of ovarian cancer
T-cell immunoglobulin and mucin domain 3 (TIM-3) is known as a negative immune regulator and emerging data have implicated TIM-3… (More)
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2013
2013
Prognostic implication of TIM-3 in clear cell renal cell carcinoma.
Clear cell renal carcinoma (ccRCC) is the most common tumor of the kidney.in adults. The prognosis of ccRCC remains… (More)
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Highly Cited
2012
Highly Cited
2012
TIM-3 Expression Characterizes Regulatory T Cells in Tumor Tissues and Is Associated with Lung Cancer Progression
BACKGROUND T cell immunoglobulin-3 (TIM-3) has been established as a negative regulatory molecule and plays a critical role in… (More)
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Highly Cited
2010
Highly Cited
2010
TIM-3 is a promising target to selectively kill acute myeloid leukemia stem cells.
Acute myeloid leukemia (AML) originates from self-renewing leukemic stem cells (LSCs), an ultimate therapeutic target for AML… (More)
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Highly Cited
2010
Highly Cited
2010
T cell/transmembrane, Ig, and mucin-3 allelic variants differentially recognize phosphatidylserine and mediate phagocytosis of apoptotic cells.
T cell/transmembrane, Ig, and mucin (TIM) proteins, identified using a congenic mouse model of asthma, critically regulate innate… (More)
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Highly Cited
2009
Highly Cited
2009
TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines.
TIM-3 is a molecule selectively expressed on a subset of murine IFN-gamma-secreting T helper 1 (Th1) cells but not Th2 cells, and… (More)
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Highly Cited
2007
Highly Cited
2007
TIM-1 and TIM-3 enhancement of Th2 cytokine production by mast cells.
Members of the T-cell immunoglobulin- and mucin-domain-containing molecule (TIM) family have roles in T-cell-mediated immune… (More)
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2006
2006
Genetic association studies between the T cell immunoglobulin mucin (TIM) gene locus and childhood atopic dermatitis.
BACKGROUND The T cell immunoglobulin mucin (TIM) gene family is involved in T cell proliferation and differentiation and has been… (More)
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