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HAVCR2 gene

Known as: T-CELL IMMUNOGLOBULIN AND MUCIN DOMAINS-CONTAINING PROTEIN 3, HAVCR2, TIMD3 
This gene plays a role in macrophage and T helper cell activation.
National Institutes of Health

Related topics

Related topics

5 relations
Hepatitis A Virus Cellular Receptor 2Immune System ProcessesImmune ToleranceMyeloid Cell Activation Process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
Universal monitoring of minimal residual disease in acute myeloid leukemia.
BACKGROUND Optimal management of acute myeloid leukemia (AML) requires monitoring of treatment response, but minimal residual… 
2018
2018
Multiplexed Immunofluorescence Analysis and Quantification of Intratumoral PD-1+ Tim-3+ CD8+ T Cells.
Immune cells are important components of the tumor microenvironment and influence tumor growth and evolution at all stages of… 
2018
2018
MiR-155 inhibits transformation of macrophages into foam cells via regulating CEH expression.
2017
2017
Synergistic effect of IL-12 and IL-18 induces TIM3 regulation of γδ T cell function and decreases the risk of clinical malaria in children living in Papua New Guinea
Backgroundγδ T cells are important for both protective immunity and immunopathogenesis during malaria infection. However, the… 
2016
2016
Abstract 3214: A fully human anti-TIM3 antibody with co-stimulatory activity
Targeting immune checkpoint molecules has been demonstrated to have significant benefit to patients with cancer. One such… 
Review
2015
Review
2015
Targeting LSCs through membrane antigens selectively or preferentially expressed on these cells.
2015
2015
Tim-3 blocking rescue macrophage and T cell function against Mycobacterium tuberculosis infection in HIV+ patients
T cell immunoglobulin and mucin domain (Tim) 3 and programmed death 1 (PD‐1) are co‐inhibitory receptors involved in the so… 
2015
2015
Profiling of primary peripheral blood- and monocyte-derived dendritic cells using monoclonal antibodies from the HLDA10 Workshop in Wollongong, Australia
Dendritic cells (DCs) arise from hematopoietic stem cells and develop into a discrete cellular lineage distinct from other… 
2015
2015
Tim-3 Induces Th2-Biased Immunity and Alternative Macrophage Activation during Schistosoma japonicum Infection
ABSTRACT T cell immunoglobulin- and mucin-domain-containing molecule 3 (Tim-3) has been regarded as an important regulatory… 
Highly Cited
2010
Highly Cited
2010
Tim3 binding to galectin-9 stimulates antimicrobial immunity
The interaction between Tim3 on Th1 cells and galectin-9 on Mycobacterium tuberculosis–infected macrophages restricts the… 
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