Immune Tolerance

Known as: Immunologic Tolerance, immune unresponsiveness, Self Tolerance 
The specific failure of a normally responsive individual to make an immune response to a known antigen. It results from previous contact with the… (More)

Topic mentions per year

Topic mentions per year

1948-2017
020040060019482016

Papers overview

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Highly Cited
2006
Highly Cited
2006
Apoptosis in the immune system is critical for maintaining self-tolerance and preventing autoimmunity. Nevertheless, inhibiting… (More)
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Highly Cited
2006
Highly Cited
2006
Regulatory T (T reg) cells are critical regulators of immune tolerance. Most T reg cells are defined based on expression of CD4… (More)
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Highly Cited
2006
Highly Cited
2006
Oral tolerance induction is a key feature of intestinal immunity, generating systemic nonresponsiveness to ingested antigens. In… (More)
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Highly Cited
2005
Highly Cited
2005
Regulatory T cells (Treg cells) expressing the forkhead family transcription factor Foxp3 are critical mediators of dominant… (More)
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Highly Cited
2003
Highly Cited
2003
Antigen-presenting cells (APCs) can induce T cell activation as well as T cell tolerance. The molecular mechanisms by which APCs… (More)
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Highly Cited
2002
Highly Cited
2002
Peripheral immune tolerance is believed to be induced by the processing and presentation of self-tissues that die during… (More)
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Highly Cited
2000
Highly Cited
2000
This report shows that cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) plays a key role in T cell-mediated dominant… (More)
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Highly Cited
1996
Highly Cited
1996
We examined the relationship between cell death and tolerance induction following antigen injection into the anterior chamber of… (More)
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Highly Cited
1995
Highly Cited
1995
Oral administration of antigen is used to induce antigen-specific peripheral immune tolerance. As well as preventing systemic… (More)
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Highly Cited
1988
Highly Cited
1988
Immunological tolerance has been demonstrated in double-transgenic mice expressing the genes for a neo-self antigen, hen egg… (More)
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