AIRE protein, human

Known as: AIRE1 protein, human, APECED protein, human, PGA1 protein, human 
Autoimmune regulator (545 aa, ~58 kDa) is encoded by the human AIRE gene. This protein is involved in both the activation of gene transcription and… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2007-2017
012320072017

Papers overview

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2016
2016
The autoimmune regulator (AIRE) is a transcription factor which is expressed in medullary thymic epithelial cells. It directs the… (More)
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2016
2016
INS-VNTR (insulin-variable number of tandem repeats) and AIRE (autoimmune regulator) have been associated with the modulation of… (More)
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2015
2015
Autoimmune regulator's (AIRE) best characterized role is in the generation immunological tolerance, but it is also involved in… (More)
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Review
2013
Review
2013
Although the role that Autoimmune Regulator (Aire) plays in the induction of central tolerance is well known, the precise… (More)
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2012
2012
The Autoimmune Regulator (AIRE) is a regulator of transcription in the thymic medulla, where it controls the expression of a… (More)
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2012
2012
Background The Autoimmune Regulator (AIRE) is a transcription factor that is involved in the negative selection of self-reactive… (More)
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Review
2011
Review
2011
In the thymus, developing T cells that react against self-antigens with high affinity are deleted in the process of negative… (More)
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2010
2010
The pathogenetic mechanisms of organ-specific autoimmune diseases remain obscured by the complexity of the genetic and… (More)
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2009
2009
Oral tolerance (OT) means systemic immunological unresponsiveness to harmless antigens present in the gastrointestinal tract. We… (More)
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2007
2007
During T cell differentiation, medullary thymic epithelial cells (MTEC) expose developing T cells to tissue-specific antigens… (More)
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