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AIRE gene

Known as: Autoimmune Regulator Gene, AUTOIMMUNE REGULATOR, autoimmune polyendocrinopathy candidiasis ectodermal dystrophy 
This gene is involved in both self-tolerance and the positive regulation of transcription.
National Institutes of Health

Related topics

Related topics

7 relations
AIRE protein, humanAPECED proteinHomo sapiensImmune Tolerance

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Cholinergic chemosensory cells of the thymic medulla express the bitter receptor Tas2r131.
2010
2010
Novel sequence variation of AIRE and detection of interferon‐ω antibodies in early infancy
Objective  Autoimmune polyendocrine syndrome type I (APS I) is a rare primary immunodeficiency disorder characterized by chronic… 
Highly Cited
2009
Highly Cited
2009
Transcription factors FoxP3 and AIRE: autoantibody associations
2009
2009
Evidence for a network transcriptional control of promiscuous gene expression in medullary thymic epithelial cells.
2008
2008
AIRE variations in Addison's disease and autoimmune polyendocrine syndromes (APS): partial gene deletions contribute to APS I
Autoimmune Addison's disease (AAD) is often associated with other components in autoimmune polyendocrine syndromes (APS). Whereas… 
2007
2007
Foxp3 and Aire in thymus-generated Treg cells: a link in self-tolerance
The transcriptional regulators Foxp3 and Aire have key functions in self-tolerance. New studies emphasize potential links between… 
2006
2006
Association analysis of the AIRE and insulin genes in Finnish type 1 diabetic patients
Mutations in the autoimmune regulator (AIRE) gene cause a recessive Mendelian disorder autoimmune polyendocrinopathy syndrome… 
Review
2005
Review
2005
Shaping the T cell repertoire to a bona fide autoantigen: lessons from autoimmune gastritis.
Highly Cited
2004
Highly Cited
2004
Good riddance: Thymocyte clonal deletion prevents autoimmunity.
1999
1999
Cloning of Aire, the mouse homologue of the autoimmune regulator (AIRE) gene responsible for autoimmune polyglandular syndrome type 1 (ASP1).
The human autoimmune regulator gene (AIRE), responsible for autoimmune polyglandular syndrome Type 1 (APS1), has recently been… 
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