Differential mucin MUC7 gene expression in invasive bladder carcinoma in contrast to uniform MUC1 and MUC2 gene expression in both normal urothelium and bladder carcinoma.

@article{Retz1998DifferentialMM,
  title={Differential mucin MUC7 gene expression in invasive bladder carcinoma in contrast to uniform MUC1 and MUC2 gene expression in both normal urothelium and bladder carcinoma.},
  author={M Retz and J Lehmann and C R{\"o}der and B M Pl{\"o}tz and J Harder and J Eggers and Jan Pauluschke and Holger Kalthoff and M St{\"o}ckle},
  journal={Cancer research},
  year={1998},
  volume={58 24},
  pages={5662-6}
}
  • M Retz, J Lehmann, +6 authors M Stöckle
  • Published 1998 in Cancer research
Mucins (MUCs) are high molecular weight membrane glycoproteins. The gene expression of MUCs (MUC1-MUC8) may change characteristically during malignant transformation of epithelial tissues. Total RNA was isolated from the four bladder cancer cell lines RT4, 647V, HT1376, and 486P (pathological gradings between G1 and G4) and 17 samples of transitional cell carcinomas, as well as 16 samples of normal human urothelium of the bladder from surgically removed specimens. The RNA samples were studied… CONTINUE READING