Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis.
Forty-three cases of obturator hernia.
Cell cycle regulation via p53 phosphorylation by a 5'-AMP activated protein kinase activator, 5-aminoimidazole- 4-carboxamide-1-beta-D-ribofuranoside, in a human hepatocellular carcinoma cell line.
- K. Imamura, T. Ogura, A. Kishimoto, M. Kaminishi, H. Esumi
- Biology, ChemistryBiochemical and Biophysical Research…
- 21 September 2001
This work found cell growth to be suppressed by AICAR treatment in HepG2 because of p53 accumulation, which was associated with p53-Ser15 phosphorylation, and a motif very similar to the consensus motif of AMPK phosphorylations was found around p53 -Ser15.
Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-β signaling
- M. Kano, Y. Bae, K. Miyazono
- Biology, MedicineProceedings of the National Academy of Sciences
- 27 February 2007
Low-dose TβR-I inhibitor altered neither TGF-β signaling in cancer cells nor the amount of fibrotic components, however, it decreased pericyte coverage of the endothelium without reducing endothelial area specifically in tumor neovasculature and promoted accumulation of macromolecules, including anticancer nanocarriers, in the tumors.
Expression and prognostic significance of prothymosin-alpha and ERp57 in human gastric cancer.
Although prothymosin-alpha is overexpressed in gastric adenocarcinoma, it is not associated with alterations in survival and loss of ERp57 expression correlated with more aggressive disease and could provide useful prognostic information for gastric cancer patients.
Gastric cancer treated in 1991 in Japan: data analysis of nationwide registry
- K. Maruyama, M. Kaminishi, Japanese Gastric Cancer Association Registration Committee
- MedicineGastric Cancer
- 1 May 2006
The Japanese Gastric Cancer Association Registration Committee reported the treatment results and causes of death of patients with primary gastric cancer treated in 1991 at the leading hospitals in Japan, finding a high proportion of early-stage cancer, high resection rate, and low mortality rate.
Lysyl Oxidase Is a Tumor Suppressor Gene Inactivated by Methylation and Loss of Heterozygosity in Human Gastric Cancers
Data showed that LOX is a tumor suppressor gene inactivated by methylation and loss of heterozygosity in gastric cancers, and possibly also in other cancers.
The presence of aberrant DNA methylation in noncancerous esophageal mucosae in association with smoking history
The objective was to elucidate the effects of smoking and drinking on the accumulation of epigenetic alterations in background mucosae in esophageal squamous cell carcinomas.
Gastric cancer treated in 2002 in Japan: 2009 annual report of the JGCA nationwide registry
Postoperative outcome of the patients with primary gastric carcinoma in Japan have apparently improved in advanced cases and among the aged population when compared with the archival data.
Gender differences in cytokine secretion by human peripheral blood mononuclear cells: role of estrogen in modulating LPS-induced cytokine secretion in an ex vivo septic model.
A gender difference in PBMCs responsiveness to LPS and E2 stimulation and E1-modulated cytokine secretion is demonstrated, which may partially explain the mechanism underlying the poorer outcome of male sepsis patients.