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Riluzole

Known as: 2-Amino-6-trifluoromethoxybenzothiazole, 2 Amino 6 trifluoromethoxybenzothiazole, 2-Amino-6-(trifluoromethoxy)benzothiazole 
A benzothiazole derivative with neuroprotective and potential anti-depressant and anxiolytic activities. While the mechanism of action of riluzole is… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Over the past decades, a multitude of experimental drugs have been shown to delay disease progression in preclinical animal… Expand
Review
2019
Review
2019
Mood disorders represent the largest cause of disability worldwide. The monoaminergic deficiency hypothesis, which has dominated… Expand
Review
2019
Review
2019
&NA; Anhedonia is defined as a diminished ability to experience interest or pleasure, and is a critical psychopathological… Expand
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Review
2018
Review
2018
Acute traumatic spinal cord injury (SCI) is a devastating event with far-reaching physical, emotional, and economic consequences… Expand
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Review
2018
Review
2018
The recent approval of edaravone has provided an intravenous option to treat amyotrophic lateral sclerosis (ALS) in addition to… Expand
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Highly Cited
1996
Highly Cited
1996
Abstract Summary Background Amyotrophic lateral sclerosis (ALS) is a progressive disease with no effective treatment. In an… Expand
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Highly Cited
1996
Highly Cited
1996
Familial amyotrophic lateral sclerosis (FALS) has been linked in some families to dominant mutations of the SOD1 gene encoding Cu… Expand
Review
1996
Review
1996
  • A. Doble
  • Neurology
  • 1996
  • Corpus ID: 19112952
The excitotoxic hypothesis of neurodegeneration has stimulated much interest in the possibility of using compounds that will… Expand
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Highly Cited
1996
Highly Cited
1996
BACKGROUND Amyotrophic lateral sclerosis (ALS) is a progressive disease with no effective treatment. In an initial study… Expand
Highly Cited
1994
Highly Cited
1994
BACKGROUND Amyotrophic lateral sclerosis is a progressive motor neuron disease for which there is no adequate treatment. Some… Expand