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Amyotrophic Lateral Sclerosis

Known as: Motor Neuron Disease, Amyotrophic Lateral Sclerosis, Gehrig Disease, Disease, Lou-Gehrigs 
A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2012
Review
2012
PURPOSE OF REVIEW The field of amyotrophic lateral sclerosis (ALS) has seen a number of remarkable advances during recent years… Expand
Review
2011
Review
2011
Amyotrophic lateral sclerosis (ALS) is an idiopathic, fatal neurodegenerative disease of the human motor system. In this Seminar… Expand
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Highly Cited
2009
Highly Cited
2009
Amyotrophic lateral sclerosis (ALS) is a fatal degenerative motor neuron disorder. Ten percent of cases are inherited; most… Expand
Highly Cited
2008
Highly Cited
2008
Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disorder characterized pathologically by ubiquitinated TAR DNA… Expand
Highly Cited
2006
Highly Cited
2006
Ubiquitin-positive, tau- and α-synuclein–negative inclusions are hallmarks of frontotemporal lobar degeneration with ubiquitin… Expand
Highly Cited
2006
Highly Cited
2006
Ubiquitin-positive tau-negative neuronal cytoplasmic inclusions and dystrophic neurites are common pathological features in… Expand
Review
2000
Review
2000
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder involving primarily motor neurons in the cerebral… Expand
Highly Cited
1994
Highly Cited
1994
BACKGROUND Amyotrophic lateral sclerosis is a progressive motor neuron disease for which there is no adequate treatment. Some… Expand
Highly Cited
1993
Highly Cited
1993
AMYOTROPHIC lateral sclerosis (ALS) is a degenerative disorder of motor neurons in the cortex, brainstem and spinal cord1,2. Its… Expand
Highly Cited
1993
Highly Cited
1993
Single-site mutants in the Cu,Zn superoxide dismutase (SOD) gene (SOD1) occur in patients with the fatal neurodegenerative… Expand