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Amyotrophic Lateral Sclerosis

Known as: Motor Neuron Disease, Amyotrophic Lateral Sclerosis, Gehrig Disease, Disease, Lou-Gehrigs 
A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Age is the main risk factor for a number of human diseases, including neurodegenerative disorders such as Alzheimer's disease… Expand
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Review
2019
Review
2019
Importance Neurofilament light protein (NfL) is elevated in cerebrospinal fluid (CSF) of a number of neurological conditions… Expand
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Review
2019
Review
2019
TAR DNA binding protein 43 (TDP-43) is a versatile RNA/DNA binding protein involved in RNA-related metabolism. Hyper… Expand
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Review
2019
Review
2019
Microglia, being the resident immune cells of the central nervous system, play an important role in maintaining tissue… Expand
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Review
2019
Review
2019
Glutamate is the primary excitatory neurotransmitter in the central nervous system (CNS) which initiates rapid signal… Expand
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Review
2019
Review
2019
Over the past decades, a multitude of experimental drugs have been shown to delay disease progression in preclinical animal… Expand
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Review
2019
Review
2019
Biomolecular condensation arising through phase transitions has emerged as an essential organizational strategy that governs many… Expand
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Review
2019
Review
2019
Oxidative stress is proposed as a regulatory element in ageing and various neurological disorders. The excess of oxidants causes… Expand
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Review
2019
Review
2019
Electrophiles and reactive oxygen species (ROS) play a major role in modulating cellular defense mechanisms as well as… Expand
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Review
2018
Review
2018
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are neurodegenerative diseases that overlap in their… Expand
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