Motor Neuron Disease

Known as: disease motor neuron, motor neurone disease, disease motor neurone 
Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1945-2018
010020030019452017

Papers overview

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Review
2016
Review
2016
Spinal muscular atrophy (SMA) is an autosomal recessive motor neuron disease with a high incidence and is the most common genetic… (More)
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Review
2016
Review
2016
Amyotrophic Lateral Sclerosis (ALS) is the most frequent motor neuron disease in adults. Classical ALS is characterized by the… (More)
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Review
2015
Review
2015
Increasing evidence suggests that the pathogenesis of neurodegenerative diseases including amyotrophic lateral sclerosis (ALS) is… (More)
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Highly Cited
2010
Highly Cited
2010
Epidemiological evidence suggests that the incidence of amyotrophic lateral sclerosis is increased in association with head… (More)
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Highly Cited
2008
Highly Cited
2008
To identify novel causes of familial neurodegenerative diseases, we extended our previous studies of TAR DNA-binding protein 43… (More)
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Highly Cited
2003
Highly Cited
2003
Impaired axonal transport in motor neurons has been proposed as a mechanism for neuronal degeneration in motor neuron disease… (More)
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Highly Cited
1997
Highly Cited
1997
The 38 kDa survival motor neuron (SMN) protein is encoded by two ubiquitously expressed genes: telomeric SMN (SMN(T)) and… (More)
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Highly Cited
1996
Highly Cited
1996
Previous work has shown that mutation of the gene that encodes the microtubule motor subunit kinesin heavy chain (Khc) in… (More)
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Highly Cited
1995
Highly Cited
1995
Mutations in Cu/Zn superoxide dismutase (SOD1) cause a subset of cases of familial amyotrophic lateral sclerosis. Four lines of… (More)
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Highly Cited
1994
Highly Cited
1994
Mutations of human Cu,Zn superoxide dismutase (SOD) are found in about 20 percent of patients with familial amyotrophic lateral… (More)
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