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AMYOTROPHIC LATERAL SCLEROSIS 1
Known as:
ALS1
, Amyotrophic Lateral Sclerosis, Familial
, AMYOTROPHIC LATERAL SCLEROSIS 1, FAMILIAL
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National Institutes of Health
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Related topics
Related topics
12 relations
Broader (1)
Amyotrophic Lateral Sclerosis
Autosomal dominant inheritance
Autosomal recessive inheritance
Genetic Heterogeneity
Muscle Cramp
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Targeted Mutagenesis, Precise Gene Editing, and Site-Specific Gene Insertion in Maize Using Cas9 and Guide RNA[OPEN]
S. Svitashev
,
Joshua K Young
,
C. Schwartz
,
Huirong Gao
,
S. Falco
,
A. Cigan
Plant Physiology
2015
Corpus ID: 7078948
Genome editing and gene insertion in maize is advanced with Cas9-guide RNA technology. Targeted mutagenesis, editing of…
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Highly Cited
2012
Highly Cited
2012
UNDERSTANDING PARTICIPATORY ACTION RESEARCH: A QUALITATIVE RESEARCH METHODOLOGY OPTION
C. Macdonald
The Canadian journal of action research
2012
Corpus ID: 20608438
Participatory Action Research (PAR) is a qualitative research methodology option that requires further understanding and…
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Highly Cited
2010
Highly Cited
2010
Mutations of optineurin in amyotrophic lateral sclerosis
H. Maruyama
,
H. Morino
,
+24 authors
H. Kawakami
Nature
2010
Corpus ID: 4361171
Amyotrophic lateral sclerosis (ALS) has its onset in middle age and is a progressive disorder characterized by degeneration of…
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Highly Cited
2010
Highly Cited
2010
FUS‐immunoreactive inclusions are a common feature in sporadic and non‐SOD1 familial amyotrophic lateral sclerosis
H. Deng
,
H. Zhai
,
+10 authors
T. Siddique
Annals of Neurology
2010
Corpus ID: 12339572
Amyotrophic lateral sclerosis (ALS) is a fatal disorder of motor neuron degeneration. Most cases of ALS are sporadic (SALS), but…
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Highly Cited
2008
Highly Cited
2008
SOD1 and Amyotrophic Lateral Sclerosis: Mutations and Oligomerization
L. Banci
,
I. Bertini
,
+4 authors
M. Vieru
PLoS ONE
2008
Corpus ID: 14571028
There are about 100 single point mutations of copper, zinc superoxide dismutase 1 (SOD1) which are reported (http://alsod.iop.kcl…
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Highly Cited
2007
Highly Cited
2007
Pathological TDP‐43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations
I. Mackenzie
,
E. Bigio
,
+17 authors
J. Trojanowski
Annals of Neurology
2007
Corpus ID: 21265303
Amyotrophic lateral sclerosis (ALS) is a common, fatal motor neuron disorder with no effective treatment. Approximately 10% of…
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Highly Cited
2006
Highly Cited
2006
Critical Role of Bcr1-Dependent Adhesins in C. albicans Biofilm Formation In Vitro and In Vivo
C. Nobile
,
D. Andes
,
+6 authors
A. Mitchell
PLoS Pathogens
2006
Corpus ID: 8631322
The fungal pathogen Candida albicans is frequently associated with catheter-based infections because of its ability to form…
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Review
2005
Review
2005
Copper-zinc superoxide dismutase and amyotrophic lateral sclerosis.
J. Valentine
,
P. A. Doucette
,
Soshanna Zittin Potter
Annual Review of Biochemistry
2005
Corpus ID: 30339766
Copper-zinc superoxide dismutase (CuZnSOD, SOD1 protein) is an abundant copper- and zinc-containing protein that is present in…
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Highly Cited
2003
Highly Cited
2003
Copper-binding-site-null SOD1 causes ALS in transgenic mice: aggregates of non-native SOD1 delineate a common feature.
Jiou Wang
,
H. Slunt
,
+5 authors
D. Borchelt
Human Molecular Genetics
2003
Corpus ID: 22726689
Cu/Zn superoxide dismutase (SOD1), a crucial cellular antioxidant, can in certain settings mediate toxic chemistry through its Cu…
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Highly Cited
1998
Highly Cited
1998
Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons
T. L. Parkes
,
A. Elia
,
D. Dickinson
,
A. Hilliker
,
J. Phillips
,
G. Boulianne
Nature Genetics
1998
Corpus ID: 33748975
Reactive oxygen (RO) has been identified as an important effector in ageing and lifespan determination. The specific cell types…
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