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Anesthetics

Known as: Anesthestic Drugs, Anaesthetic Agent, anesthetic drug 
A drug or other substance that causes a loss of feeling or awareness. Local anesthetics cause a loss of feeling in one small area of the body… 
National Institutes of Health

Related topics

Related topics

49 relations

Narrower (36)

1-hexanolChloroformEnfluraneEthrane
Adjuvants, AnesthesiaAnalgesicsAnesthesia proceduresAnesthesiology

Broader (2)

Central Nervous System DepressantsPharmaceutical Preparations

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
Halothane, isoflurane and sevoflurane inhibit NADH: ubiquinone oxidoreductase (complex I) of cardiac mitochondria
We have investigated the effects of volatile anaesthetics on electron transport chain activity in the mammalian heart. Halothane… 
Highly Cited
1996
Highly Cited
1996
Laboratory animal anaesthesia
Highly Cited
1995
Highly Cited
1995
Stereoselective block of a human cardiac potassium channel (Kv1.5) by bupivacaine enantiomers.
Highly Cited
1989
Highly Cited
1989
Clinical evaluation of propofol as an intravenous anaesthetic agent in cats and dogs
The clinical efficacy and safety of an emulsion containing 10 mg/ml of the intravenous anaesthetic propofol were evaluated in… 
Highly Cited
1988
Highly Cited
1988
Volatile general anaesthetics activate a novel neuronal K+ current
Although it is still controversial whether the primary target sites underlying general anaesthesia are proteins1,2 or lipids3–5… 
Highly Cited
1987
Highly Cited
1987
Phencyclidine and related drugs bind to the activated N-methyl-d-aspartate receptor-channel complex in rat brain membranes
Highly Cited
1982
Highly Cited
1982
General anesthetics hyperpolarize neurons in the vertebrate central nervous system.
The effect of general anesthetics on frog motoneurons and rat hippocampus pyramidal cells was examined with sucrose gap and… 
Highly Cited
1978
Highly Cited
1978
Where do general anaesthetics act?
General anaesthetics were found to have no effect on lipid bilayer structures when studied using X-ray and neutron diffraction… 
Highly Cited
1976
Highly Cited
1976
Model for action of local anaesthetics
Sodium channels in nerve membranes are postulated to be surrounded by lipid molecules in the gel (or crystalline) phase. Addition… 
Highly Cited
1972
Highly Cited
1972
The effects of anaesthetics on synaptic excitation and inhibition in the olfactory bulb
1. The effects of anaesthetics (pentobarbitone, hexobarbitone, halothane, urethane, chloralose, chloral hydrate and ethanol) on… 
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