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Lipid rafts: at a crossroad between cell biology and physics
Membrane lateral heterogeneity is accepted as a requirement for the function of biological membranes and the notion of lipid rafts gives specificity to this broad concept. However, the lipid raft… Expand
Phase equilibria in the phosphatidylcholine-cholesterol system.
- J. Ipsen, G. Karlström, O. Mouritsen, H. Wennerström, M. Zuckermann
- Chemistry, Medicine
- Biochimica et biophysica acta
- 27 November 1987
A thermodynamic and a microscopic interaction model are proposed to describe the phase equilibria in the phosphatidylcholine-cholesterol system. The model calculations allow for a solid phase with… Expand
Physical properties of the fluid lipid-bilayer component of cell membranes: a perspective.
The motivation for this review arises from the conviction that, as a result of the mass of experimental data and observations collected in recent years, the study of the physical properties of… Expand
Life - As a Matter of Fat
Prologue: Lipidology - the science of lipids.- I THE OVERLOOKED MOLECULES.- Life from molecules.- Head and tail.- Oil and water.- Lipids speak the language of curvature.- A matter of softness.- Soft… Expand
An outlook on organization of lipids in membranes: searching for a realistic connection with the organization of biological membranes.
- L. Bagatolli, J. Ipsen, A. Simonsen, O. Mouritsen
- Chemistry, Medicine
- Progress in lipid research
- 1 October 2010
Lipid-bilayer membranes are formed by self-assembly processes. The molecular interactions within the bilayer and with the environment impart a unique trans-bilayer lateral pressure profile and… Expand
On the human consumption of the red seaweed dulse (Palmaria palmata (L.) Weber & Mohr)
- O. Mouritsen, C. Dawczynski, L. Duelund, G. Jahreis, W. Vetter, M. Schröder
- Journal of Applied Phycology
- 27 March 2013
The red seaweed dulse (Palmaria palmata) is one of the more popular seaweed species for human consumption in the Western world. With a documented historical use up to present days in Ireland,… Expand
Mattress model of lipid-protein interactions in membranes.
A thermodynamic model is proposed for describing phase diagrams of mixtures of lipid bilayers and amphiphilic proteins or polypeptides in water solution. The basic geometrical variables of the model… Expand
What's so special about cholesterol?
Cholesterol (or other higher sterols such as ergosterol and phytosterols) is universally present in large amounts (20–40 mol%) in eukaryotic plasma membranes, whereas it is universally absent in the… Expand
Lipids do influence protein function-the hydrophobic matching hypothesis revisited.
A topical review of the current state of lipid-protein interactions is given with focus on the physical interactions between lipids and integral proteins in lipid-bilayer membranes. The concepts of… Expand
Relationships between lipid membrane area, hydrophobic thickness, and acyl-chain orientational order. The effects of cholesterol.
A microscopic interaction model for a fully hydrated lipid bilayer membrane containing cholesterol is used to calculate, as a function of temperature and composition, the membrane area, the membrane… Expand