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Receptor, Endothelin A

Known as: Endothelin A Receptor, Receptors, Endothelin A, Endothelin Receptors Type A 
A subtype of endothelin receptor found predominantly in the VASCULAR SMOOTH MUSCLE. It has a high affinity for ENDOTHELIN-1 and ENDOTHELIN-2.
National Institutes of Health

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Related topics

7 relations
EDNRA geneIn Bloodagonistsaspects of radiation effects

Narrower (2)

Endothelin-1 Receptor, Humandear protein, rat

Papers overview

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Review
2008
Review
2008
The endothelin axis in cancer.
Highly Cited
2007
Highly Cited
2007
Endothelin-1 Vasoconstrictor Tone Increases With Age in Healthy Men But Can Be Reduced by Regular Aerobic Exercise
Increased endothelin-1–mediated vasoconstrictor tone has been linked to the etiology of a number of pathologies associated with… 
Highly Cited
2001
Highly Cited
2001
Expression and Localization of Endothelin Receptors: Implications for the Involvement of Peripheral Glia in Nociception
The endothelins (ETs) are peptides that have a diverse array of functions mediated by two receptor subtypes, the endothelin A… 
Highly Cited
1998
Highly Cited
1998
Role of Endothelin-1/Endothelin-A receptor-mediated signaling pathway in the aortic arch patterning in mice.
The intercellular signaling mediated by endothelins and their G protein-coupled receptors has recently been shown to be essential… 
Highly Cited
1996
Highly Cited
1996
Heterozygous endothelin receptor B (EDNRB) mutations in isolated Hirschsprung disease.
Hirschsprung disease (HSCR, aganglionic megacolon) is a frequent congenital malformation regarded as a multigenic… 
Highly Cited
1995
Highly Cited
1995
Endothelin in coronary endothelial dysfunction and early atherosclerosis in humans.
BACKGROUND The endothelium modulates vascular tone through release of vasodilating substances, such as endothelium-derived… 
Highly Cited
1994
Highly Cited
1994
Interaction of endothelin-3 with endothelin-B receptor is essential for development of epidermal melanocytes and enteric neurons
Highly Cited
1993
Highly Cited
1993
The human endothelin-B receptor gene. Structural organization and chromosomal assignment.
Highly Cited
1992
Highly Cited
1992
Plasma endothelin immunoreactivity in liver disease and the hepatorenal syndrome.
BACKGROUND Severe renal vasoconstriction is central to the pathogenesis of renal failure in the hepatorenal syndrome. Endothelin… 
Highly Cited
1990
Highly Cited
1990
Women with preeclampsia have higher plasma endothelin levels than women with normal pregnancies.
Endothelin, a newly discovered endothelium-derived peptide, has potent vasoactive properties in vivo and in vitro. The actions of… 
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