Skip to search formSkip to main contentSkip to account menu

Endothelin-1 Receptor, Human

Known as: Endothelin A Receptor, ETA-R, ET-A 
Endothelin-1 receptor (427 aa, ~49 kDa) is encoded by the human EDNRA gene. This protein is a multipass transmembrane protein that is a receptor for… 
National Institutes of Health

Related topics

Related topics

13 relations
EDNRA geneG Protein-Coupled Receptor GenesG Protein-Coupled Receptor SignalingIntegral Membrane Proteins

Broader (1)

Receptor, Endothelin A

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Major role for hypoxia inducible factor-1 and the endothelin system in promoting myocardial infarction and hypertension in an animal model of obstructive sleep apnea.
Highly Cited
2009
Highly Cited
2009
Contribution of Endothelin A Receptors in Endothelin 1–Dependent Natriuresis in Female Rats
Renal medullary endothelin B receptors contribute to blood pressure regulation by facilitating salt excretion. Premenopausal… 
Highly Cited
2007
Highly Cited
2007
Peripheral endothelin A receptor antagonism attenuates carcinoma‐induced pain
Highly Cited
2006
Highly Cited
2006
Leptin Regulates Cardiomyocyte Contractile Function Through Endothelin-1 Receptor–NADPH Oxidase Pathway
Leptin, the obese gene product, plays an important role in the regulation of cardiac function. However, the mechanism behind… 
Review
2001
Review
2001
The role of endothelins and their receptors in heart failure.
Endothelin (ET) is a peptide composed of 21 amino acids, derived from a larger precursor, the big-endothelin, by action of the… 
1999
1999
Characterization of endothelin-1 receptor subtypes in isolated human cardiomyocytes.
On cardiac membranes and isolated cardiomyocytes from the human heart, cell-type distribution and functional activities of… 
Highly Cited
1997
Highly Cited
1997
The orally active nonpeptide endothelin A-receptor antagonist A-127722 prevents and reverses hypoxia-induced pulmonary hypertension and pulmonary vascular remodeling in Sprague-Dawley rats.
Exposure to hypoxia is associated with increased pulmonary artery pressure and plasma endothelin (ET-1) levels and with selective… 
Highly Cited
1994
Highly Cited
1994
Physiologic characterization of endothelin A and B receptor activity in the ovine fetal pulmonary circulation.
To determine the potential contribution of endothelin (ET) to modulation of high pulmonary vascular resistance in the normal… 
Highly Cited
1993
Highly Cited
1993
The endothelin-1 receptor antagonist BQ-123 reduces infarct size in a canine model of coronary occlusion and reperfusion.
OBJECTIVE The aim was to determine the effect of the endothelin-1 receptor antagonist, BQ-123, on infarct size in anaesthetised… 
Highly Cited
1991
Highly Cited
1991
Cloning and expression of human endothelin‐1 receptor cDNA
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License