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Endothelin-1 Receptor, Human
Known as:
Endothelin A Receptor
, ETA-R
, ET-A
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Endothelin-1 receptor (427 aa, ~49 kDa) is encoded by the human EDNRA gene. This protein is a multipass transmembrane protein that is a receptor for…
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National Institutes of Health
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Related topics
Related topics
13 relations
EDNRA gene
G Protein-Coupled Receptor Genes
G Protein-Coupled Receptor Signaling
Integral Membrane Proteins
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Broader (1)
Receptor, Endothelin A
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Differential modulation of the expression of important drug metabolising enzymes and transporters by endothelin-1 receptor antagonists ambrisentan and bosentan in vitro.
J. Weiss
,
Melanie Herzog
,
W. Haefeli
European Journal of Pharmacology
2011
Corpus ID: 19458147
2010
2010
Abnormal protein expression in the corpus cavernosum impairs erectile function in type 2 diabetes
W. Chiou
,
Hui‐Kang Liu
,
C. Juan
BJU International
2010
Corpus ID: 205541735
Study Type – Aetiology (case control) Level of Evidence 3b
2008
2008
Common genetic variation in the type A endothelin-1 receptor is associated with ambulatory blood pressure: a family study
T. Rahman
,
M. Baker
,
D. Hall
,
P. Avery
,
B. Keavney
Journal of Human Hypertension
2008
Corpus ID: 22026243
The endothelins are among the most potent vasoconstrictors known. Pharmacological inhibition of endothelin receptors lowers blood…
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2005
2005
Effects of a dual endothelin-1 receptor antagonist on airway obstruction and acute lung injury in sheep following smoke inhalation and burn injury.
R. Cox
,
Perenlei Enkhabaatar
,
+7 authors
D. Traber
Clinical science
2005
Corpus ID: 39374355
Studies have suggested that ET-1 (endothelin-1) is associated with lung injury, airway inflammation and increased vascular…
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Highly Cited
2002
Highly Cited
2002
A pivotal role for cADPR‐mediated Ca2+ signaling: regulation of endothelin‐induced contraction in peritubular smooth muscle cells
Fortunata Barone
,
A. Genazzani
,
+6 authors
A. Filippini
The FASEB Journal
2002
Corpus ID: 14899855
cADPR, a potent calcium‐mobilizing intracellular messenger synthesized by ADP‐ribosyl cyclases regulates openings of ryanodine…
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2001
2001
Intrathecal administration of endothelin-1 receptor antagonist ameliorates autoimmune encephalomyelitis in Lewis rats
T. Shin
,
Bongsu Kang
,
+4 authors
Jongchul Kang
NeuroReport
2001
Corpus ID: 29578731
The role of endothelin-1(ET-1) in the development of experimental autoimmune encephalomyelitis (EAE) was studied by the blocking…
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2000
2000
Endothelin and free radicals modulate microvascular responses in streptozotocin-induced diabetic rats.
M. Bassirat
,
Z. Khalil
Microvascular Research
2000
Corpus ID: 20009142
The quantitative contribution of endothelin and free radicals in modulating peripheral endothelial and smooth muscle-dependent…
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1997
1997
Additional hypotensive effect of endothelin-1 receptor antagonism in hypertensive dogs under angiotensin-converting enzyme inhibition.
J. Donckier
,
P. Massart
,
+6 authors
G. Heyndrickx
Circulation
1997
Corpus ID: 10856395
BACKGROUND Endothelin-1 (ET-1) may play a role in hypertension. ET-1 receptor antagonism by bosentan lowers blood pressure in…
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1995
1995
Effects of endothelin-1 and endothelin-A receptor antagonist on recovery after hypothermic cardioplegic ischemia in neonatal lamb hearts.
T. Hiramatsu
,
J. Forbess
,
T. Miura
,
S. Roth
,
M. Cioffi
,
J. Mayer
Circulation
1995
Corpus ID: 29606439
BACKGROUND Prior studies suggest an important role for coronary endothelium in ischemia/reperfusion (I/R) injury. Decreased…
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1989
1989
Identification of the Endothelin‐1 Receptor in the Chick Heart
H. Miyazaki
,
M. Kondoh
,
+7 authors
T. Masaki
Journal of Cardiovascular Pharmacology
1989
Corpus ID: 40950810
Summary This study suggests that binding sites for endothelin-1 (ET-1) are distinct from those for dihydropyridine (DHP…
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