Quinolinate

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1953-2018
0102019532017

Papers overview

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2006
2006
Excessive activation of NMDA receptors results in excitotoxic nerve cell loss, which is believed to play a critical role in the… (More)
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2004
Highly Cited
2004
Huntington's disease (HD), an inherited neurodegenerative disorder, is caused by an abnormal polyglutamine expansion in the… (More)
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2003
2003
Previous studies have demonstrated two different biosynthetic pathways to quinolinate, the universal de novo precursor to the… (More)
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2003
Highly Cited
2003
There are different theories and hypotheses related to the aetiology of depression. The interaction between brain 5-HT level and… (More)
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2002
Highly Cited
2002
Previous work suggests N-methyl-D-aspartate receptor (NMDAR) activation may be involved in degeneration of medium-sized spiny… (More)
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2000
2000
Quinolate acid phosphoribosyltransferase (QPRTase), a key enzyme in nicotinamide adenine dinucleotide (NAD) biosynthesis, also… (More)
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1997
1997
Quinolinate, an endogenous excitotoxic metabolite of tryptophan with affinity to the N-methyl-D-aspartate type of glutamate… (More)
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Highly Cited
1991
Highly Cited
1991
The effects on the expression of a conditioned place preference of bilateral, excitotoxic amino acid-induced lesions of the… (More)
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1987
1987
The central neurotoxicity of the endogenous tryptophan metabolite, quinolinate, has been postulated to participate in the… (More)
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1986
Highly Cited
1986
Exposure of cultures of cortical cells from mouse to either of the endogenous excitatory neurotoxins quinolinate or glutamate… (More)
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