Convulsants

Known as: convulsant 
Substances that act in the brain stem or spinal cord to produce tonic or clonic convulsions, often by removing normal inhibitory tone. They were… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Cannabis sativa has been associated with contradictory effects upon seizure states despite its medicinal use by numerous people… (More)
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Highly Cited
2005
Highly Cited
2005
Rodent seizure models have significantly contributed to our basic understanding of epilepsy. However, medically intractable forms… (More)
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Highly Cited
2003
Highly Cited
2003
Abnormally high spiking activity can damage neurons. Signaling systems to protect neurons from the consequences of abnormal… (More)
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Highly Cited
2000
Highly Cited
2000
Retigabine [N-(2-amino-4-[fluorobenzylamino]-phenyl) carbamic acid; D-23129] is a novel anticonvulsant, unrelated to currently… (More)
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Highly Cited
1999
Highly Cited
1999
Using immunocytochemistry and ELISA, we investigated the production of interleukin (IL)-1beta in the rat hippocampus after focal… (More)
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1990
1990
1. Succinimide derivatives can be either convulsant (tetramethylsuccinimide (TMS)), or anticonvulsant (ethosuximide (ES); alpha… (More)
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Highly Cited
1989
Highly Cited
1989
This study evaluated the systemic toxicity, arrhythmogenicity, and mode of death of convulsant and supraconvulsant doses of… (More)
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Highly Cited
1988
Highly Cited
1988
Administration of the convulsants pentylenetetrazole (Metrazole) or picrotoxin to rats caused a dramatic increase in mRNAs of… (More)
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Highly Cited
1987
Highly Cited
1987
A dramatic and specific induction of c-fos was observed in identifiable neuronal populations in vivo after administration of the… (More)
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Highly Cited
1982
Highly Cited
1982
Kynurenine and related compounds are endogenous metabolites of tryptophan which have previously been found to be convulsant in… (More)
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