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Convulsants

Known as: convulsant 
Substances that act in the brain stem or spinal cord to produce tonic or clonic convulsions, often by removing normal inhibitory tone. They were… Expand
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
Abnormally high spiking activity can damage neurons. Signaling systems to protect neurons from the consequences of abnormal… Expand
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Highly Cited
2000
Highly Cited
2000
Retigabine [N-(2-amino-4-[fluorobenzylamino]-phenyl) carbamic acid; D-23129] is a novel anticonvulsant, unrelated to currently… Expand
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Highly Cited
1987
Highly Cited
1987
A dramatic and specific induction of c-fos was observed in identifiable neuronal populations in vivo after administration of the… Expand
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Highly Cited
1987
Highly Cited
1987
The decline in the high incidence of amyotrophic lateral sclerosis, parkinsonism, and Alzheimer-type dementia among the Chamorro… Expand
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Highly Cited
1987
Highly Cited
1987
Certain steroids are potent barbiturate-like modulators of the gamma-aminobutyric acidA (GABA) receptor-chloride ionophore… Expand
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Highly Cited
1982
Highly Cited
1982
Abstract Kynurenine and related compounds are endogenous metabolites of tryptophan which have previously been found to be… Expand
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Highly Cited
1980
Highly Cited
1980
Abstract Kainic acid has been injected unilaterally into the amygdaloid complex of rats. Electro-encephalographic and clinical… Expand
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Highly Cited
1978
Highly Cited
1978
From the following three lines of evidence, it is proposed that at least part of the convulsant activity of naloxone is a result… Expand
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Highly Cited
1976
Highly Cited
1976
The sodium‐dependent high affinity choline uptake into synaptosomes from rat brain has been studied after in vivo treatments… Expand
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Highly Cited
1971
Highly Cited
1971
Summary (1) A study has been made of the effects of bicuculline, a phthalide isoquinoline convulsant alkaloid, on the inhibition… Expand
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