• Publications
  • Influence
N-Nitroso compounds in the diet.
  • W. Lijinsky
  • Biology, Medicine
  • Mutation research
  • 15 July 1999
N-Nitroso compounds were known almost 40 years ago to be present in food treated with sodium nitrite, which made fish meal hepatotoxic to animals through formation of nitrosodimethylamine (NDMA).Expand
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  • PDF
Chemistry and Biology of N-Nitroso Compounds
Glossary Foreword Acknowledgements 1. Introduction 2. Occurence, formation and detection of N-nitroso compounds 3. Chemical properties of N-nitroso compunds 4. Metabolism and cellular interactions ofExpand
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The formation and occurrence of polynuclear aromatic hydrocarbons associated with food.
  • W. Lijinsky
  • Biology, Medicine
  • Mutation research
  • 1 March 1991
Polynuclear aromatic hydrocarbons are common contaminants of processed food, usually at trace levels. These hydrocarbons are products of combustion and pyrolysis, and are present in petroleum andExpand
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Nitrosamines as Environmental Carcinogens
Human cancer might be caused by nitrosamines formed in the body from ingested nitrites and secondary amines. Cooking could be a source of secondary amines.
  • 594
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Mutagenicity of vinyl compounds in Salmonella typhimurium.
Eighteen compounds structurally related to the mutagenic carcinogen vinyl chloride have been tested for mutagenicity in five strains of Salmonella typhimurium. Acrolein, acrolein diethylacetal,Expand
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Maternal prenatal exposure to nitrosatable drugs and childhood brain tumours.
BACKGROUND A compelling hypothesis was proposed that childhood brain tumours are associated with maternal exposure to N-nitroso compounds during the prenatal period. Many common drugs, such asExpand
  • 41
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Feeding tests in rats on mixtures of nitrite with secondary and tertiary amines of environmental importance.
The possible formation of N-nitroso compounds in vivo from ingested secondary or tertiary amines and nitrite was tested with 13 amino compounds selected on the basis of their widespread availabilityExpand
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Alkylation of rat liver nucleic acids not related to carcinogenesis by N-nitrosamines.
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Carcinogenesis in rats by aflatoxins B1, G1, and B2.
Summary Aflatoxins B1, G1, and B2 of high purity have been prepared from a crude mixture of aflatoxins and have been tested by long-term feeding in drinking water to rats, at concentrations of 1Expand
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Purification and Toxicity of Aflatoxin Gl.∗
Summary A method for quantitative analysis of crude aflatoxin mixtures is described, using thin layer chromatography and absorption spectrometry. Highly purified aflatoxin G l has been prepared byExpand
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