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N-Nitroso compounds in the diet.
  • W. Lijinsky
  • Chemistry, Medicine
  • Mutation research
  • 15 July 1999
TLDR
Levels of nitrosamines have been declining during the past three decades, concurrent with a lowering of the nitrite used in food and greater control of exposure of malt to nitrogen oxides in beer making. Expand
Chemistry and Biology of N-Nitroso Compounds
Glossary Foreword Acknowledgements 1. Introduction 2. Occurence, formation and detection of N-nitroso compounds 3. Chemical properties of N-nitroso compunds 4. Metabolism and cellular interactions ofExpand
The formation and occurrence of polynuclear aromatic hydrocarbons associated with food.
  • W. Lijinsky
  • Biology, Medicine
  • Mutation research
  • 1 March 1991
TLDR
Sophisticated analytical methods, using solvent extraction and chromatography have been developed to detect and measure polynuclear aromatic hydrocarbons at levels of 1 in 10(9) (1 part per billion) or less, and these have been applied to the measurement of individual compounds in foods, as well as in products of combustion and pyrolysis. Expand
Agricultural pesticide use and risk of glioma in Nebraska, United States
TLDR
The authors found significant associations between some specific agricultural pesticide exposures and the risk of glioma among male farmers but not among female farmers in Nebraska; however, most of the positive associations were limited to proxy respondents. Expand
Nitrosamines as Environmental Carcinogens
Human cancer might be caused by nitrosamines formed in the body from ingested nitrites and secondary amines. Cooking could be a source of secondary amines.
Maternal consumption of cured meats and vitamins in relation to pediatric brain tumors.
TLDR
This largest study to date of maternal diet and childhood brain tumors suggests that exposure during gestation to endogenously formed nitroso compounds may be associated with tumor occurrence. Expand
Altered incidences of hepatic and hemopoietic neoplasms in F344 rats fed sodium nitrite.
TLDR
The incidence of liver neoplasms, which were carcinomas and neoplastic nodules, in the two groups of females treated with sodium nitrite in feed was significantly higher than in the controls, but there was no significant difference in the males. Expand
Maternal prenatal exposure to nitrosatable drugs and childhood brain tumours.
TLDR
Findings do not support an association between maternal use of nitrosatable drugs during pregnancy and brain tumour risk in offspring. Expand
Alkylation of rat liver nucleic acids not related to carcinogenesis by N-nitrosamines.
  • W. Lijinsky, A. Ross
  • Chemistry, Medicine
  • Journal of the National Cancer Institute
  • 1 June 1969
Mutagenicity of vinyl compounds in Salmonella typhimurium.
Eighteen compounds structurally related to the mutagenic carcinogen vinyl chloride have been tested for mutagenicity in five strains of Salmonella typhimurium. Acrolein, acrolein diethylacetal,Expand
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