Quinolines

Known as: 1 benzazine, Quinolines [Chemical/Ingredient], quinoline 
 
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
As a disease-modifying approach for Alzheimer's disease (AD), clioquinol (CQ) targets beta-amyloid (Abeta) reactions with… (More)
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Review
2006
Review
2006
Although three new drugs or drug formulations, liposomal amphotericin B (AmBisome), miltefosine and paromomycin should be… (More)
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Highly Cited
2005
Highly Cited
2005
Neurofibrillary tangles (NFTs), neuropil threads, and neuritic elements of senile plaques predominantly comprise… (More)
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Review
2005
Review
2005
Plasmodium falciparum is the most important parasitic pathogen in humans, causing hundreds of millions of malaria infections and… (More)
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Review
2004
Review
2004
Two subclasses of quinoline antimalarial drugs are used clinically. Both act on the endolysosomal system of malaria parasites… (More)
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Highly Cited
1999
Highly Cited
1999
The malaria parasite feeds by degrading haemoglobin in an acidic food vacuole, producing free haem moieties as a by-product. The… (More)
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Review
1997
Review
1997
Hemoglobin degradation in intraerythrocytic malaria parasites is a vast process that occurs in an acidic digestive vacuole… (More)
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Highly Cited
1996
Highly Cited
1996
Chloroquine is thought to exert its antimalarial effect by preventing the polymerization of toxic heme released during… (More)
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Highly Cited
1994
Highly Cited
1994
Polymerisation of haematin to beta-haematin (haemozoin or malaria pigment) in acidic acetate solutions was studied using infrared… (More)
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Highly Cited
1983
Highly Cited
1983
The in vitro activity of Bay 09867, a new quinoline derivative, was compared with those of norfloxacin, nalidixic acid… (More)
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